ID: 1
InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several
CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
ID: 23
InChIKey: ZNNLBTZKUZBEKO-UHFFFAOYSA-N SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
biological descriptors:
CFTR relevance: CFTR BlockerCategory:
Influence on CFTR function inhibits CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment
CID is 3488
synonyms found at PubChem are:
Glibenclamide, glyburide, 10238-21-8, Glybenclamide, Micronase, Diabeta, Glynase, Daonil, Euglucon, Maninil, Semi-daonil, Apo-Glibenclamide, Euglucon 5, Azuglucon, Bastiverit, Benclamin, Betanase, Duraglucon, Euglucan, Euglykon, Glibenil, Glucolon, Neogluconin, Orabetic, Prodiabet, Renabetic, Yuglucon, Dibelet, Gilemal, Glibens, Glibil, Glimel, Glimide, Humedia, Libanil, Suraben, Tiabet, Adiab, Glybenzcyclamide, Melix, Pira, Med-Glionil, Gewaglucon, Glibenbeta, Glibenclamida, Glibenclamidum, Glucohexal, Glucoremed, Hexaglucon, Lisaglucon, Normoglucon, Praeciglucon, Calabren, Cytagon, Euclamin, Glamide, Glibesyn, Glibetic, Gliboral, Glidiabet, Glisulin, Glitisol, Glubate, Glucobene, Glucomid, Glucoven, Glycomin, Lederglib, Miglucan, Debtan, Gliban, Gliben, Glibet, Glicem, Gluben, Glyben, Nadib, Sugril, Novo-Glyburide, Glibenclamid AL, Gen-Glybe, Norglicem 5, Betanese 5, Glibenclamid Fabra, Glibenclamid Basics, Glibenclamid-Cophar, Glibenclamid Heumann, Semi-Euglucon, Glibenclamid Genericon, Hemi-Daonil, Glibenclamid-Ratiopharm, Glibenclamidum [INN-Latin], Glibenclamida [INN-Spanish], Abbenclamide, HB 419, Diabiphage, Glibadone, Semi-Gliben-Puren N, GBN 5, Glibenclamid Riker M., Glyburide (micronized), Euglucon N, 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide, Micronized glyburide, Glyburide [USAN], UR 606, Glimidstata, Glycolande, Glycron, PresTab, Gluco-Tablimen, Dia-basan, UNII-SX6K58TVWC, 1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea, Gliben-Puren N, Micronase (TN), C23H28ClN3O5S, Glyburide (USP), HB-419, 1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, Diabeta (TN), Glynase (TN), Glibenclamid Riker M, 5-Chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide, U 26452, glyburide (glibenclamide), EINECS 233-570-6, HB-420, SX6K58TVWC, CHEMBL472, BRN 2230085, N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea, MLS000069721, CHEBI:5441, 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide, Urea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexyl-, Benzamide, 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-, NCGC00015467-11, SMR000058229, CAS-10238-21-8, 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, G 0639, Urea, 1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-, 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide, DSSTox_CID_17237, DSSTox_RID_79313, N-(4-(beta-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff, DSSTox_GSID_37237, U-26452, Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, W-108874, 1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, 1-{4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea;1-{4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea, GIBENCLAMIDE, SR-01000000196, Glyburide [USAN:USP], glicuformine, Delmide, HB419, HB420, Euglucon (TN), Glibenclamide,(S), 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide, GBM, Prestwick_569, Glibenclamide B.P., Daonil (TN), Glyburide (Diabeta), HB 420, Semi-Daonil (TN), Glibenclamide [INN], RP-1127, Spectrum_000250, Tocris-0911, Opera_ID_801, Prestwick0_000316, Prestwick1_000316, Prestwick2_000316, Prestwick3_000316, Spectrum2_001816, Spectrum3_001327, Spectrum4_001199, Spectrum5_001631, Lopac-G-0639, ACMC-20a66i, D05LYX, Probes1_000431, Probes2_000378, UPCMLD-DP006, AC1L1G1Q, Glibenclamide (JP15/INN), Glibenclamide (JP17/INN), CBiol_001790, Lopac0_000499, Oprea1_764617, SCHEMBL22009, BSPBio_000312, BSPBio_001351, BSPBio_003053, KBioGR_000071, KBioGR_001897, KBioSS_000071, KBioSS_000730, MLS001077262, BIDD:GT0239, DivK1c_000481, SPECTRUM2300229, SPBio_001831, SPBio_002531, AC1Q44V7, BPBio1_000344, GTPL2414, DTXSID0037237, UPCMLD-DP006:001, CTK8B7917, HMS501I03, KBio1_000481, KBio2_000071, KBio2_000730, KBio2_002639, KBio2_003298, KBio2_005207, KBio2_005866, KBio3_000141, KBio3_000142, KBio3_002273, AOB6214, SYN3026, Glybenclamide, >=99% (HPLC), MolPort-000-784-850, NINDS_000481, ZNNLBTZKUZBEKO-UHFFFAOYSA-N, Bio1_000076, Bio1_000565, Bio1_001054, Bio2_000071, Bio2_000551, HMS1361D13, HMS1568P14, HMS1791D13, HMS1922L08, HMS1989D13, HMS2089L06, HMS2093P04, HMS2095P14, HMS3259O12, HMS3261D19, HMS3267A15, HMS3402D13, HMS3428D15, HMS3651E17, HMS3712P14, Pharmakon1600-02300229, ZINC537805, BCP05327, Tox21_110158, Tox21_300758, Tox21_500499, ANW-58936, BDBM50012957, BG0207, CCG-39618, GP8701, HD 419, MFCD00056625, NSC759618, SBB057426, STK362992, AKOS001487495, Tox21_110158_1, BCP9000729, CS-1075, DB01016, KS-5326, LP00499, MCULE-2351642942, NC00566, NSC-759618, IDI1_000481, IDI1_033821, Glibenclamide 1.0 mg/ml in Acetonitrile, NCGC00015467-01, NCGC00015467-02, NCGC00015467-03, NCGC00015467-04, NCGC00015467-05, NCGC00015467-06, NCGC00015467-07, NCGC00015467-08, NCGC00015467-09, NCGC00015467-10, NCGC00015467-12, NCGC00015467-13, NCGC00015467-14, NCGC00015467-15, NCGC00015467-16, NCGC00015467-17, NCGC00015467-18, NCGC00015467-20, NCGC00015467-36, NCGC00016689-01, NCGC00023447-02, NCGC00023447-04, NCGC00023447-05, NCGC00023447-06, NCGC00023447-07, NCGC00023447-08, NCGC00023447-09, NCGC00023447-10, NCGC00023447-11, NCGC00023447-12, NCGC00254662-01, NCGC00261184-01, 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide, AJ-23371, AN-20367, CPD000058229, HY-15206, KB-73471, SAM002564212, SC-17437, ST024780, SBI-0050483.P003, AB0012611, AB2000243, Glyburide, meets USP testing specifications, LS-159295, RT-000122, AB00051949, EU-0100499, FT-0601608, G0382, S1716, A19539, C07022, D00336, J10021, W-5054, 78637-EP2270001A1, 78637-EP2270011A1, 78637-EP2272825A2, 78637-EP2272841A1, 78637-EP2275414A1, 78637-EP2287165A2, 78637-EP2287166A2, 78637-EP2292620A2, 78637-EP2298750A1, 78637-EP2298776A1, 78637-EP2298779A1, 78637-EP2301923A1, 78637-EP2301936A1, 78637-EP2305648A1, 78637-EP2308847A1, AB00051949-16, AB00051949-17, AB00051949_18, AB00051949_19, C-22898, I06-0716, SR-01000000196-2, SR-01000000196-4, SR-01000000196-5, SR-01000000196-6, SR-01000000196-8, U-26,452, BRD-K36927236-001-06-0, BRD-K36927236-001-17-7, Z277540138, Glybenclamide, European Pharmacopoeia (EP) Reference Standard, Glyburide, United States Pharmacopeia (USP) Reference Standard, 1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl urea, 5-Chloro-N-[4-(3-cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)-phenethyl)-2-methoxybenzamide, 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxy-benzamide, 5-chloro-N-[4-({[(cyclohexylamino)carbonyl]amino}sulfonyl)phenethyl]-2-methoxybenzamide, Glibenclamide for peak identification, European Pharmacopoeia (EP) Reference Standard, Glyburide (Glibenclamide), Pharmaceutical Secondary Standard; Certified Reference Material, N-(4-(.beta.-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N -cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N'-cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N-cyclohexylurea, (5-chloro-2-methoxyphenyl)-N-[2-(4-{[(cyclohexylamino)carbonylamino]sulfonyl}p henyl)ethyl]carboxamide, 5-Chloro-N-(2-[4-(([(cyclohexylamino)carbonyl]amino)sulfonyl)phenyl]ethyl)-2-methoxybenzamide #, 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide, N-[(4-{2-[(5-chloro-2-methoxyphenyl)carbonylamino]ethyl}phenyl)sulfonyl](cyclo hexylamino)carboxamide