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InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several

reference list:

ReferenceID: 71
"YC Yu" "Y Sohma" "TC Hwang"
ReferenceID: 59
"AM Vonk" "KM de Winter-de Groot" "P Van Mourik" "CK van der Ent" "JM Beekman" "HR de Jonge" "HM Janssens" "G Berkers" "E Kruisselbrink" "I Bronsveld" "JF Dekkers"
ReferenceID: 107
"C Coraux" "L Froux" "F Becq" "E Sage"
ReferenceID: 54
"LJ Galietta" "N Pedemonte" "F Cateni" "MT Mazzei" "P Fossa" "M Giampieri" "M Mazzei" "M Zacchigna"
ReferenceID: 2
"BT Conger" "D Skinner" "SM Rowe" "SB Hicks" "S Zhang" "BA Woodworth" "EJ Sorscher"
ReferenceID: 30
"K Shah" "NA Bradbury" "I Dey"
ReferenceID: 24
"GM Roomans" "Z Servetnyk" "C Andersson"
ReferenceID: 9
"M Carattino" "L Suaud" "RC Rubenstein" "TR Kleyman"
ReferenceID: 12
"MJ Baker" "KL Hamilton"
ReferenceID: 80
"A Hazlewood" "P Negulescu" "F Van Goor" "T Knapp" "S Hadida" "J Rader" "PD Grootenhuis" "M Miller" "E Olson" "KS Straley" "R Tung" "A Singh" "J González" "LR Makings" "J Joubran" "V Panchenko" "D Cao" "T Neuberger" "JH Stack"
ReferenceID: 53
"GW Carlile" "E Matthes" "D Rotin" "B Kus" "J Liao" "J Goepp" "SD Macknight" "DY Thomas" "R Robert" "JW Hanrahan"
ReferenceID: 20
"LJ Galietta" "P Fanen" "O Zegarra-Moran" "C Folli" "G Cabrini" "E Caci" "Y Mettey" "F Becq" "JM Vierfond" "L Romio"
ReferenceID: 16
"CO Randak" "LS Ostedgaard" "DW Vermeer" "AL Berger" "PH Karp" "MJ Welsh"
ReferenceID: 65
"K Schoonderwoerd" "MJ Bijvelds" "AB Houtsmuller" "CH Lim" "BC Tilly" "HR de Jonge" "A Nigg"
ReferenceID: 72
"PA Sloane" "J Fulton" "L Fan" "K Varga" "J Fortenberry" "JP Clancy" "EJ Sorscher" "Y Li" "B Woodworth" "SM Rowe" "LC Pyle" "J Collawn" "A Jurkevante" "M Mazur"
ReferenceID: 1
"S Noël" "L Dannhoffer" "M Wilke" "Y Mettey" "F Becq" "H DeJonge" "PO Strale" "C Rogier"
ReferenceID: 101
"VR Villella" "A Tosco" "L Maiuri" "G Kroemer" "M Piacentini" "V Raia"
ReferenceID: 43
"A Schmidt" "LK Hughes" "H Li" "F Mendes" "MD Amaral" "Z Cai" "DN Sheppard"
ReferenceID: 51
"MF Springsteel" "L Al-Nakkash" "MJ Kurth" "MH Nantz"
ReferenceID: 68
"LJ Galietta" "R Melani" "O Zegarra-Moran" "V Tomati"
ReferenceID: 34
"E Kwon" "PL Zeitlin" "AD Floyd" "K McKenzie" "M Lim"
ReferenceID: 36
"O Zegarra-Moran" "O Moran"
ReferenceID: 3
"S Waldegger" "A Bachmann" "U Quast" "U Russ"
ReferenceID: 19
"YC Yu" "M Yasui" "Y Matsuzaki" "A Hanyuda" "H Miki" "Y Sohma" "TC Hwang" "Y Abe" "SG Bompadre" "Y Nakamura" "K Tanaka"
ReferenceID: 93
"NL Quinney" "IG Chaudhry" "R Schlegel" "C Cho" "C Cheluvaraju" "M Gentzsch" "SH Randell" "X Liu" "SE Boyles" "H Dang"
ReferenceID: 48
"YJ Chen" "L Al-Nakkash" "LL Clarke" "GE Rottinghaus" "K Cooper" "LJ Rubin"
ReferenceID: 11
"PC Chao" "KL Hamilton"
ReferenceID: 17
"K Bernard" "KL Kirk" "W Wang" "G Li"
ReferenceID: 32
"LJ Galietta" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Kurth" "MJ Haddadin" "AS Verkman" "K By" "MH Nantz"
ReferenceID: 49
"TC Hwang" "SG Bompadre" "S Hu" "M Li" "X Wang" "T Ai"
ReferenceID: 41
"K Backer" "PA Sloane" "SM Rowe" "JP Clancy" "J Prasain" "LC Pyle" "M Mazur" "S Barnes" "JC Fulton"

chemical graph of compound 1





CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one