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InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several

reference list:

ReferenceID: 36
"O Zegarra-Moran" "O Moran"
ReferenceID: 49
"SG Bompadre" "S Hu" "X Wang" "TC Hwang" "M Li" "T Ai"
ReferenceID: 101
"V Raia" "A Tosco" "VR Villella" "G Kroemer" "L Maiuri" "M Piacentini"
ReferenceID: 34
"M Lim" "K McKenzie" "PL Zeitlin" "E Kwon" "AD Floyd"
ReferenceID: 43
"Z Cai" "H Li" "A Schmidt" "MD Amaral" "LK Hughes" "DN Sheppard" "F Mendes"
ReferenceID: 1
"F Becq" "H DeJonge" "Y Mettey" "S Noël" "L Dannhoffer" "M Wilke" "C Rogier" "PO Strale"
ReferenceID: 59
"AM Vonk" "JM Beekman" "HM Janssens" "P Van Mourik" "I Bronsveld" "JF Dekkers" "CK van der Ent" "G Berkers" "E Kruisselbrink" "KM de Winter-de Groot" "HR de Jonge"
ReferenceID: 20
"F Becq" "C Folli" "Y Mettey" "E Caci" "L Romio" "O Zegarra-Moran" "LJ Galietta" "G Cabrini" "P Fanen" "JM Vierfond"
ReferenceID: 9
"L Suaud" "TR Kleyman" "M Carattino" "RC Rubenstein"
ReferenceID: 2
"S Zhang" "EJ Sorscher" "BA Woodworth" "SM Rowe" "D Skinner" "BT Conger" "SB Hicks"
ReferenceID: 80
"LR Makings" "M Miller" "J Rader" "J González" "JH Stack" "KS Straley" "PD Grootenhuis" "J Joubran" "E Olson" "A Singh" "T Knapp" "P Negulescu" "D Cao" "S Hadida" "R Tung" "F Van Goor" "V Panchenko" "T Neuberger" "A Hazlewood"
ReferenceID: 48
"LL Clarke" "GE Rottinghaus" "YJ Chen" "L Al-Nakkash" "LJ Rubin" "K Cooper"
ReferenceID: 72
"PA Sloane" "L Fan" "A Jurkevante" "SM Rowe" "JP Clancy" "B Woodworth" "M Mazur" "EJ Sorscher" "LC Pyle" "K Varga" "Y Li" "J Fortenberry" "J Fulton" "J Collawn"
ReferenceID: 12
"MJ Baker" "KL Hamilton"
ReferenceID: 30
"K Shah" "NA Bradbury" "I Dey"
ReferenceID: 107
"F Becq" "C Coraux" "E Sage" "L Froux"
ReferenceID: 19
"SG Bompadre" "Y Nakamura" "A Hanyuda" "TC Hwang" "Y Matsuzaki" "H Miki" "Y Abe" "Y Sohma" "K Tanaka" "M Yasui" "YC Yu"
ReferenceID: 51
"MH Nantz" "MJ Kurth" "L Al-Nakkash" "MF Springsteel"
ReferenceID: 54
"F Cateni" "MT Mazzei" "P Fossa" "M Giampieri" "M Zacchigna" "N Pedemonte" "LJ Galietta" "M Mazzei"
ReferenceID: 68
"V Tomati" "O Zegarra-Moran" "R Melani" "LJ Galietta"
ReferenceID: 32
"MH Nantz" "AS Verkman" "MJ Kurth" "K By" "M Eda" "MJ Haddadin" "LJ Galietta" "MF Springsteel" "EJ Niedzinski"
ReferenceID: 53
"J Liao" "GW Carlile" "DY Thomas" "J Goepp" "JW Hanrahan" "B Kus" "D Rotin" "R Robert" "SD Macknight" "E Matthes"
ReferenceID: 3
"U Quast" "U Russ" "S Waldegger" "A Bachmann"
ReferenceID: 65
"K Schoonderwoerd" "AB Houtsmuller" "CH Lim" "BC Tilly" "HR de Jonge" "MJ Bijvelds" "A Nigg"
ReferenceID: 16
"LS Ostedgaard" "AL Berger" "CO Randak" "DW Vermeer" "MJ Welsh" "PH Karp"
ReferenceID: 71
"TC Hwang" "Y Sohma" "YC Yu"
ReferenceID: 11
"PC Chao" "KL Hamilton"
ReferenceID: 17
"W Wang" "KL Kirk" "K Bernard" "G Li"
ReferenceID: 41
"M Mazur" "LC Pyle" "PA Sloane" "SM Rowe" "K Backer" "S Barnes" "JP Clancy" "J Prasain" "JC Fulton"
ReferenceID: 24
"C Andersson" "GM Roomans" "Z Servetnyk"
ReferenceID: 93
"C Cheluvaraju" "X Liu" "SH Randell" "SE Boyles" "NL Quinney" "IG Chaudhry" "H Dang" "M Gentzsch" "C Cho" "R Schlegel"


CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one