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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"O Zegarra-Moran" "E Caci" "F Becq" "L Romio" "P Fanen" "Y Mettey" "JM Vierfond" "G Cabrini" "C Folli" "LJ Galietta"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=3

ID: 1
InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several

chemical graph of compound 1



CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

ID: 14
InChIKey: FFBDFADSZUINTG-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3CCCC3

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function inconsistent assignment
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 14



CID is 1329
synonyms found at PubChem are:
8-Cyclopentyl-1,3-dipropylxanthine, DPCPX, 102146-07-6, 8-cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione, 1,3-Dpcpx, 1,3-dipropyl-8-cyclopentylxanthine, PD-116,948, PD-116948, GNF-PF-2224, UNII-9PTP4FOI9E, dipropylcyclopentylxanthine, 9PTP4FOI9E, CHEMBL183, MLS000069347, 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione, CHEBI:73282, 8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione, SMR000058434, DPCPX, 1,3-Dipropyl-8-cyclopentylxanthine, 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX], 8-cyclopentyl-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione, 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-, PD 116948, Spectrum_000271, Tocris-0439, Opera_ID_160, Lopac-C-101, Spectrum2_001808, Spectrum3_001073, Spectrum4_001228, Spectrum5_001887, [DPCPX], D0K0OT, D0OW4Q, AC1L1B8K, Lopac0_000381, BSPBio_002686, GTPL386, KBioGR_001696, KBioSS_000751, MLS001076525, DivK1c_000177, SCHEMBL382422, SPECTRUM2300063, SPBio_001795, SCHEMBL1094807, SCHEMBL12648692, BCBcMAP01_000212, BDBM21173, CTK8B4471, HMS500I19, KBio1_000177, KBio2_000751, KBio2_003319, KBio2_005887, KBio3_001906, DTXSID50144706, OR9885T, FFBDFADSZUINTG-UHFFFAOYSA-N, MolPort-003-666-763, NINDS_000177, HMS2235C14, HMS3261M03, HMS3266O21, HMS3369D05, ZINC3977757, ZX-AT022179, DPCPX; PD 116,948, Tox21_500381, ANW-45129, CCG-39732, PDSP1_000448, PDSP1_001208, PDSP2_000446, PDSP2_001192, AKOS015900114, AKOS024458134, CCG-221685, DB12946, EX-3308, LP00381, VZ31021, IDI1_000177, KS-0000186U, NCGC00015177-01, NCGC00015177-02, NCGC00015177-03, NCGC00015177-04, NCGC00015177-05, NCGC00015177-06, NCGC00015177-07, NCGC00015177-08, NCGC00015177-09, NCGC00015177-10, NCGC00015177-11, NCGC00023294-02, NCGC00023294-04, NCGC00023294-05, NCGC00023294-06, NCGC00023294-07, NCGC00261066-01, AJ-47554, AK-88727, CC-23366, KB-53263, PD116948, SC-91856, 8-Cyclopentyl-1,3-dipropylxanthine, solid, AX8008808, LS-126534, ST2406601, B6305, EU-0100381, FT-0621530, X8593, C13709, C-18978, L000233, SR-01000003000, SR-01000075202, SR-01000003000-2, SR-01000075202-1, W-200660, BRD-K01824921-001-02-9, BRD-K01824921-001-10-2, I14-10012, 8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H);-dione, 8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

ID: 15
InChIKey: FLJBLCAZPFDCPE-UHFFFAOYSA-O
SMILES: C1=CC2=CC(=O)C3=C([NH+]2C=C1)C(=CC=C3)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function inconsistent assignment
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 15



CID is 9795308
synonyms found at PubChem are:
CHEMBL175225, SCHEMBL5738619, CHEMBL1181524, BDBM50139822, 10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chloride, MPB-07