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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"E Matthes" "R Solari" "R Andersen" "R Hatley" "V Birault" "R Robert" "JW Hanrahan" "Q Yang" "GW Carlile" "CM Edge" "DY Thomas"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=8
ID: 697
InChIKey: GGCJGNBVVMDYKM-UHFFFAOYSA-N
SMILES: C1C2=NC(=NC=C2C3=C(C(=O)N1)NC(=C3Br)Br)N

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

chemical graph of compound 697



CID is 11440210
synonyms found at PubChem are:
Latonduine A, SCHEMBL13042347
ID: 3036
InChIKey: VRKZEOFXEIZHKY-UHFFFAOYSA-N
SMILES: C(O)1CNC(=O)C2[NH0]C(Br)=C(C)C=2C=1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3036



ID: 3066
InChIKey: YXSQRBVTVVVHEQ-UHFFFAOYSA-N
SMILES: C1CNC(=O)C2[NH0]C(Br)=C(Br)C=2C=1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3066



ID: 3074
InChIKey: ZTTHLXXJDFDDCO-UHFFFAOYSA-N
SMILES: C1CNC(=O)C2[NH0]C=CC=2C=1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3074



ID: 3048
InChIKey: WMNXVNCBIDSIQZ-UHFFFAOYSA-N
SMILES: C1CNC(=O)C2[NH0]C(C)=C(C)C=2C=1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3048



ID: 2887
InChIKey: BPXKJGXZDJAJEW-UHFFFAOYSA-N
SMILES: C2=CC1=C([N]C(=C1Br)C)C(=O)NC2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2887



ID: 3031
InChIKey: VFYMPIDZJNUFJK-UHFFFAOYSA-N
SMILES: C1CNC(=O)C2[NH0]C(Br)=C(C)C=2C=1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3031



ID: 3049
InChIKey: WQEAXCMYYLABKB-UHFFFAOYSA-N
SMILES: C2(=CC1=C([N]C(=C1Br)C)C(=O)NC2)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3049