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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"TC Hwang" "S Hu" "M Li" "SG Bompadre" "T Ai" "X Wang"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=2

ID: 1
InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several

chemical graph of compound 1



CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

ID: 84
InChIKey: YKPUWZUDDOIDPM-SOFGYWHQSA-N
SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC

biological descriptors:

CFTR relevance: CFTR potentiator, increase in opening rate, decrease in closing rate

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 84



CID is 1548943
synonyms found at PubChem are:
Capsaicin, 404-86-4, Zostrix, CAPSAICINE, (E)-Capsaicin, Qutenza, Styptysat, Axsain, Isodecenoic acid vanillylamide, E-CAPSAICIN, trans-8-Methyl-N-vanillyl-6-nonenamide, NGX-4010, Capsaicin [USAN], Caswell No. 158, Transacin, (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-Capsaicin, NCI-C56564, NGX 4010, UNII-S07O44R1ZM, FEMA No. 3404, CCRIS 1588, CHEBI:3374, HSDB 954, C18H27NO3, Capsaicin (JAN/USP), 8-Methyl-N-Vanillyl-6-Nonenamide, 6-Nonenamide, 8-methyl-N-vanillyl-, (E)-, ZOSTRIX (TN), N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide, EINECS 206-969-8, NSC 56353, EPA Pesticide Chemical Code 070701, BRN 2816484, 8-Methyl-N-vanillyl-6-nonenamide, (E)-, (e)-n-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, CHEMBL294199, S07O44R1ZM, YKPUWZUDDOIDPM-SOFGYWHQSA-N, (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (6E)-, NSC56353, Capsaicin [in oleoresin of capsicum], trans-Capsaicin-d3, NCGC00017337-02, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, (E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide, (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, DSSTox_CID_241, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (E)-, N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-, DSSTox_RID_75455, DSSTox_GSID_20241, Ausanil, (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide, [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, 6-Nonenamide, (E)-N-((4-hydroxy-3-methoxy-phenyl)methyl)-8-methyl, Capsaicin (in oleoresin of capsicum), (6E)-N-{[4-hydroxy-3-(methyloxy)phenyl]methyl}-8-methylnon-6-enamide, 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (6E)-, 8-Methyl-N-vanillyl-trans-6-nonenamide, CAPSAICIN, NATURAL, SR-05000001861, neurotoxic, Isodecenoate, Capsicin, Capsicine, Vanilloid, Mioton, N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, Adlea, TNP00277, Capsaicin Patch, (E)-N-[(4-Hydroxy-3-methoxyphenyl)-methyl]-8-methyl-6-nonenamide, ALGRX 4975, epsilon-capsaicin, Zostrix HP, Capsaicin,(S), Capsaicin(Qutenza), CAS-404-86-4, Prestwick_204, Capsaicin (Natural), depletes Substance P, 1217899-52-9, Citrus Aurantium 30%, Capsaicin [USP:INN], Citrus Aurantium Extract, 6-Nonenamide, (E)-, Prestwick2_000879, Prestwick3_000879, Spectrum5_000538, CITRUS AURANTIUM PE, D0U5CE, UPCMLD-DP092, AC1LU7K3, Bitter orange extract 30%, SCHEMBL8085, SCHEMBL8086, MR3H3, BSPBio_000957, BSPBio_001548, BSPBio_002917, MLS002154049, trans-8-Methyl-N-vanillylnon, Capsaicin, analytical standard, SPECTRUM1501128, Capsaicin, from natural source, AC1Q46B3, BPBio1_001053, GTPL2486, MEGxp0_001448, n-(4-hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide, (E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE, DTXSID9020241, UPCMLD-DP092:001, UPCMLD-DP092:002, BDBM20461, BDBM86537, CHEBI:94524, HMS501B16, MolPort-001-742-263, HMS1361N10, HMS1570P19, HMS1791N10, HMS1921H11, HMS1989N10, HMS2089N11, HMS2092D21, HMS2097P19, HMS2230O23, HMS3402N10, HMS3649N15, Pharmakon1600-01501128, 8-Methyl-N-vanillyl-6E-nonenamide, NGX-1998, NGX-3781, NGX-7325, NSC_2548, ZINC1530575, Tox21_110817, Tox21_200315, BBL027836, CC0144, CCG-39908, EI-125, LMFA08020085, MFCD00017259, N0C781, NSC-56353, NSC757844, STL372889, (E)-N-(4-Hydroxy-3-methoxybenzyl), (E)8-methyl-N-vanillyl-6-Nonenamide, AKOS007930159, CS-1518, DB06774, KS-5181, LS-2138, MCULE-8056866140, NSC-757844, RTC-030399, SDCCGMLS-0066678.P001, TQ-1018, Capsaicin, >=95%, from Capsicum sp., IDI1_000354, IDI1_034018, SMP2_000337, NCGC00017337-03, NCGC00017337-04, NCGC00017337-05, NCGC00017337-06, NCGC00017337-07, NCGC00017337-08, NCGC00017337-09, NCGC00017337-10, NCGC00017337-11, NCGC00017337-12, NCGC00017337-13, NCGC00017337-18, NCGC00090853-01, NCGC00090853-02, NCGC00090853-03, NCGC00090853-04, NCGC00090853-06, NCGC00090853-07, NCGC00090853-08, NCGC00090853-09, NCGC00090853-10, NCGC00090853-11, NCGC00090853-12, NCGC00257869-01, AC-10114, AJ-26667, AN-23437, CAS_404-86-4, CJ-23980, HY-10448, N735, SC-19636, SMR000718774, ST057183, Nonenamide, 8-methyl-N-vanillyl-, (E)-, SBI-0052593.P002, TC-030399, TL8002946, 4CH-016296, FT-0082538, M1149, N1667, (E)-8-Methyl-N-vanillyl-6-nonenamide(8cl), C06866, D00250, W-5044, AB00053098-11, AB00053098_12, Capsaicin, from Capsicum sp., >=50% (HPLC), 6-Nonenamide, 8-methyl-N-vanillyl-, (E)- (8CI), I01-2469, SR-05000001861-1, SR-05000001861-4, SR-05000001861-5, SR-05000001861-6, SR-05000001861-9, BRD-K37056290-001-01-1, BRD-K50590187-001-06-6, Capsaicin, certified reference material, TraceCERT(R), N-(3-Methoxy-4-hydroxybenzyl)-8-methyl-6-nonenamide, N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, Capsaicin (transdermal patch formulation, neuropathic pain), Capsaicin, European Pharmacopoeia (EP) Reference Standard, UNII-UW86K581WY component YKPUWZUDDOIDPM-SOFGYWHQSA-N, (6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide #, Capsaicin, United States Pharmacopeia (USP) Reference Standard, CAPSAICIN (2444-46-4 NONIVAMIDE (SYNTHETIC CAPSAICIN)), trans-N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material, Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8 -methyl-, (E)-, 912457-62-6