previous reference ID: 81 next reference

CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"JW Hanrahan" "DY Thomas" "E Matthes" "J Liao" "HM Sampson" "GW Carlile" "R Robert"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=3

ID: 2880
InChIKey: BAVRWDCSJSFVNJ-LDADJPATSA-N
SMILES: C1=CC=C(C=C1)N/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]

biological descriptors:

CFTR relevance: CFTR chaperone binding to NBD1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

chemical graph of compound 2880



CID is 9566157
synonyms found at PubChem are:
5-(4-Nitrophenyl)-2-furaldehyde 2-phenylhydrazone, (1E)-1-{[5-(4-nitrophenyl)furan-2-yl]methylidene}-2-phenylhydrazine, CHEMBL3585378, CCG-684, BAVRWDCSJSFVNJ-LDADJPATSA-N, MolPort-001-828-272, STK001879, AKOS001588752, 5-(4-Nitrophenyl)-2-furaldehyde phenylhydrazone #, SR-01000631014-1

ID: 2994
InChIKey: PMAIUMUDXRAWIA-RIYZIHGNSA-N
SMILES: CN/N=C/C1=CC=C(O1)C2=CC=C(C=C2)[N+](=O)[O-]

biological descriptors:

CFTR relevance: no effect

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2994



CID is 5899356
synonyms found at PubChem are:
AC1NZ3F4, CCG-683, MolPort-002-912-560, N-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]methanamine

ID: 2908
InChIKey: FAXXFIOVHFSKRF-ZVBGSRNCSA-N
SMILES: C1=CC(=C(C=C1N/N=C/C2=CC=C(O2)C3=C(C=C(C=C3)[N+](=O)[O-])Br)C(=O)O)Cl

biological descriptors:

CFTR relevance: CFTR chaperone binding to NBD1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

chemical graph of compound 2908



CID is 9604668
synonyms found at PubChem are:
MolPort-002-161-272