previous compound ID: 1027 next compound
InChIKey: IZMYWEXQNFYSRZ-UHFFFAOYSA-N
SMILES: C1C2C(C(=O)N)=C(NC(C3CCCCC3)=O)SC=2CCC1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"GL Lukacs" "K Du" "LJ Galietta" "RK Guy" "T Ma" "A Taddei" "N Pedemonte" "AA Shelat" "VS Gopinath" "H Yang" "AS Verkman" "C Folli"

chemical graph of compound 1027




CID is 675676
synonyms found at PubChem are:
CHEMBL209562, 2-[(cyclohexylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 142995-02-6, 2-(cyclohexanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, AC1LDUWQ, Cambridge id 6993511, Oprea1_477124, ARONIS001749, SCHEMBL3126680, ZINC38517, IZMYWEXQNFYSRZ-UHFFFAOYSA-N, MolPort-001-501-026, BDBM50185103, STK095320, AKOS000491344, MCULE-4335105668, KS-00003V54, BAS 04054141, ST054630, BB0278962, EU-0008292, UNM000003541001, AK-968/12120287, SR-01000463330, SR-01000463330-1, Z27358490, 2-cyclohexaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(Cyclohexanecarbonyl-amino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid amide, 2-(cyclohexanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(cyclohexylcarbonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide