previous compound ID: 1050 next compound
InChIKey: JDUMTSOFUMWLJQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NC2=C(OC3=CC=CC=C32)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"GL Lukacs" "H Yang" "LJ Galietta" "A Taddei" "AS Verkman" "C Folli" "VS Gopinath" "K Du" "RK Guy" "T Ma" "N Pedemonte" "AA Shelat"

chemical graph of compound 1050





CID is 570268
synonyms found at PubChem are:
3-benzamidobenzofuran-2-carboxamide, 3-benzamido-1-benzofuran-2-carboxamide, 68217-75-4, JDUMTSOFUMWLJQ-UHFFFAOYSA-N, 3-Benzoylamino-benzofuran-2-carboxylic acid amide, AC1LC69T, Cambridge id 6432655, Oprea1_760585, MLS000528875, SCHEMBL3118545, CHEMBL1308755, CTK7F8402, ZINC58361, CHEBI:115706, MolPort-001-964-434, HMS1692O04, HMS2313B21, STK070406, AKOS000507241, MCULE-7381463762, BAS 01508074, SMR000121350, ST079168, Benzofuran-2-carboxamide, 3-benzoylamino-, 2-benzofurancarboxamide, 3-(benzoylamino)-, 3-(Benzoylamino)-1-benzofuran-2-carboxamide, EU-0017189, 3-(Benzoylamino)-1-benzofuran-2-carboxamide #, 3-(phenylcarbonylamino)benzo[b]furan-2-carboxamide, 3-[(phenylcarbonyl)amino]-1-benzofuran-2-carboxamide, F0834-0768, Z108545860, A0111/0004866