previous compound ID: 1327 next compound
InChIKey: LXMSZDCAJNLERA-ZHYRCANASA-N
SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53
"SD Macknight" "B Kus" "J Goepp" "JW Hanrahan" "GW Carlile" "D Rotin" "J Liao" "R Robert" "DY Thomas" "E Matthes"

chemical graph of compound 1327





CID is 5833
synonyms found at PubChem are:
spironolactone, 52-01-7, Aldactone, Spirolactone, Verospiron, Euteberol, Spiroctan, Spirolang, Verospirone, Aldactone A, Spironocompren, Melarcon, Spiresis, Spiridon, Uractone, Urusonin, Acelat, Alderon, Spirone, Xenalon, Dira, Spiro-Tablinen, Spironolactone A, spironolattone, Aquareduct, Espironolactona, Spironolactonum, Aldopur, Aldactazide, Aldace, Almatol, Deverol, Altex, Spironolattone [DCIT], Abbolactone, Veroshpiron, Aldactide, Berlactone, Duraspiron, Spiractin, SC 9420, Spironolactonum [INN-Latin], Espironolactona [INN-Spanish], Spiroctanie, Spirolakton, Diatensec, Lacalmin, Lacdene, Laractone, Nefurofan, Sagisal, Sincomen, Spiretic, Spiroderm, Spirolone, Sprioderm, Suracton, Osyrol, Supra-puren, Aldactone (TN), Verospirone Opianin, SC-9420, Spironolactone [BAN:INN:JAN], Spironolactone [INN:BAN:JAN], UNII-27O7W4T232, C24H32O4S, HSDB 3184, EINECS 200-133-6, NSC 150399, BRN 0057767, CHEMBL1393, SC 15983, CHEBI:9241, Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan), 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone, 27O7W4T232, Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-, SNL, 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone acetate, 3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone, 3-(3-Keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic acid lactone, DSSTox_CID_14186, DSSTox_RID_79120, DSSTox_GSID_34186, 17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate, S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate, Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan], Jenaspiron, Spirogamma, Spirospare, Diatense, Flumach, Frumikal, Practon, Spirobeta, Spironone, NovoSpiroton, Novo Spiroton, Novo-Spiroton, Spirono Isis, Spirono-Isis, 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone, spiro von ct, 4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate, von ct, spiro, (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan]-6'-ene-5,5'-dione, 17-alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-alpha-mercapto-3-oxo-, gamma-lactone acetate, SMR000471892, Espironolactona Alter, Spiro L.U.T., Espironolactona Mundogen, quimolactona, spirotone, Spiranolactone, Carospir, 2oax, 3vhu, Berlactone (TN), CAS-52-01-7, Verospiron (TN), Spiractin (TN), Spirotone (TN), Aldactazide (TN), NCGC00015948-02, 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alpha.-yl)propionic acid lactone, 7-.alpha.-(acetylthio)-17-.alpha.-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, .gamma.-lactone, CPD000471892, S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate, S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate, Spironolactone [USP:INN:BAN:JAN], SC9420, Novo-Spiroton (TN), Prestwick0_000128, Prestwick1_000128, Prestwick2_000128, Prestwick3_000128, D0EP0C, AC1L1L8Q, Dexo Brand of Spironolactone, BIDD:PXR0071, SCHEMBL20939, BSPBio_000176, 4-18-00-01601 (Beilstein Handbook Reference), Alter Brand of Spironolactone, MLS001074672, MLS001333253, MLS001333254, MLS002153245, MLS002207058, MLS002548846, Roche Brand of Spironolactone, Cardel Brand of Spironolactone, Pfizer Brand of Spironolactone, Searle Brand of Spironolactone, SPBio_002115, Worwag Brand of Spironolactone, BPBio1_000194, GTPL2875, Alpharma Brand of Spironolactone, DTXSID6034186, Hormosan Brand of Spironolactone, Mundogen Brand of Spironolactone, betapharm Brand of Spironolactone, Ashbourne Brand of Spironolactone, Azupharma Brand of Spironolactone, Generosan Brand of Spironolactone, Jenapharm Brand of Spironolactone, Novopharm Brand of Spironolactone, Alphapharm Brand of Spironolactone, LXMSZDCAJNLERA-ZHYRCANASA-N, MolPort-033-355-721, Pharmafrid Brand of Spironolactone, Spironolactone (JP15/USP/INN), Spironolactone (JP17/USP/INN), HMS1568I18, HMS2090N21, HMS2095I18, HMS2236E06, HMS3259G11, HMS3712I18, Merck dura Brand of Spironolactone, ACT02596, HY-B0561, KS-00000FA6, Spironolactone, 97.0-103.0%, ZINC3861599, Tox21_113047, Tox21_302154, BDBM50228080, MFCD00082250, NSC150399, s4054, AKOS015896401, AC-4214, CCG-220128, CS-2670, ct Arzneimittel Brand of Spironolactone, ct-Arzneimittel Brand of Spironolactone, DB00421, KS-5234, Mayoly-Spindler Brand of Spironolactone, MCULE-4394091100, NC00482, NSC-150399, NCGC00164397-01, NCGC00164397-02, NCGC00164397-03, NCGC00164397-05, NCGC00255229-01, BC204094, H490, SC-15112, Spironolactone 1.0 mg/ml in Acetonitrile, AB1009415, LS-118614, AB00513806, LT00772287, S0260, 7080-EP2269989A1, 7080-EP2270011A1, 7080-EP2272841A1, 7080-EP2295406A1, 7080-EP2298772A1, 7080-EP2298776A1, 7080-EP2301936A1, 7080-EP2308562A2, 7080-EP2308839A1, C07310, D00443, EN300-123035, AB01275520-01, AB01275520_02, 082S250, SR-01000765419, SR-05000000452, I06-1970, Q-201737, SR-01000765419-2, SR-05000000452-2, BRD-K90027355-001-03-4, BRD-K90027355-001-19-0, Z1551900341, Spironolactone, European Pharmacopoeia (EP) Reference Standard, WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ, 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone acetate, Spironolactone, United States Pharmacopeia (USP) Reference Standard, 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, acetate, Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, (7.alpha.,17.alpha.)-, (7?,17?)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid ?-lactone, 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone, 7alpha-(Acetylthio)-17alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone, Spironolactone for system suitability, European Pharmacopoeia (EP) Reference Standard, (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadecan]-6'-ene-5,5'-dione, 1050678-93-7, 17-HYDROXY-7ALPHA-MERCAPTO-3-OXO-17ALPHA-PREGN-4-ENE-21- CARBOXYLIC ACID, GAMMA-LACTONE ACETATE, 2'',15''-dimethyl-5,5''-dioxo-(9''R)-spiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate, 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate, 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate(Spiranolactone), 4-Pregnen-21-oic acid-17|A-ol-3-one-7|A-thiol |A-lactone 7-acetate; 7|A-(Acetylthio)-17|A-hydroxy-3-oxopregn-4-ene-21-carboxylic acid |A-lactone, 496916-40-6, 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI), S-(2''R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5''-dioxo-1,2,3,4'',5'',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3''H-spiro[cyclopenta[a]phenanthrene-17,2''-furan]-7-yl ethanethioate, Spiro(17H-cyclopenta(a)phenanthrene-17,2'(5'H)-furan), pregn-4-ene-21-carboxylic acid deriv