Galietta LJ et. al. 2001 (paper)
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.The Journal of biological chemistry, page 19723-8, volume 276, issue 23, year 2001
"M Eda"
"MF Springsteel"
"AS Verkman"
"LJ Galietta"
"MH Nantz"
"K By"
"MJ Haddadin"
"EJ Niedzinski"
"MJ Kurth"
DOI:
10.1074/jbc.M101892200 PMID:
11262417
Reference Into Function: Compounds of the 7,8-benzoflavone class, which are structurally intermediate between flavones and benzo[c]quinoliziniums, were effective CFTR activators with the most potent being 2-(4-pyridinium)benzo[h]4H-chromen-4-one bisulfate (UCcf-029). Compounds of the novel structural class of fused pyrazolo heterocycles were also strong CFTR activators with the most potent being 3-(3-butynyl)-5-methoxy-1-phenylpyrazole-4-carbaldehyde (UCcf-180).
CID is 15458986 the link to PubChem record is
https://pubchem.ncbi.nlm.nih.gov/compound/15458986
CID is
15458986
synonyms found at PubChem are:
27473-55-8, 3-(2-Furanyl)-5-isoxazolemethanol, AKOS022358200, (3-(furan-2-yl)isoxazol-5-yl)methanol, 5-Isoxazolemethanol, 3-(2-furanyl)- (9CI)
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