previous compound ID: 1486 next compound
InChIKey: NKHBKSNSNVGJOE-UHFFFAOYSA-N
SMILES: CC(C1=NC2=CC=CC=C2C(=N1)N3CCCCC3)N4CCN(CC4)S(=O)(=O)C5=CC=C(C=C5)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 72
"B Woodworth" "K Varga" "J Fortenberry" "J Fulton" "J Collawn" "A Jurkevante" "JP Clancy" "SM Rowe" "LC Pyle" "L Fan" "M Mazur" "PA Sloane" "EJ Sorscher" "Y Li"

chemical graph of compound 1486




CID is 23632303
synonyms found at PubChem are:
SCHEMBL1084332, VRT-640, KB-13518, 2-(1-{4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl}ethyl)-4-(1-piperidinyl)quinazoline, quinazoline, 2-[1-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]ethyl]-4-(1-piperidinyl)-