previous compound ID: 167 next compound
InChIKey: AQLAXCGHPBMFIJ-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)OCC(C(C)C)N.I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53

Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"DY Thomas" "JW Hanrahan" "GW Carlile" "E Matthes" "R Robert" "B Kus" "SD Macknight" "J Liao" "D Rotin" "J Goepp"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 167



CID is 11957611 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/11957611

CID is 11957611
synonyms found at PubChem are:
R(-)-Me5 hydriodide, R(-)-Me5, 1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydriodide, EU-0100772, MLS002153485, R(-)-Me5 hydriodide, solid, CHEMBL1480136, CTK8G2721, Tox21_500772, CCG-222076, LP00772, NCGC00094111-01, NCGC00261457-01, SMR001230832, M 0814, SR-01000075975, SR-01000075975-1, 1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydroiodide, 1173019-55-0