previous compound ID: 1833 next compound
InChIKey: QKAALLVQBOLELJ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=C2)S(=O)(=O)NCCCCN)C(=C1)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53


Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"JW Hanrahan" "R Robert" "GW Carlile" "B Kus" "DY Thomas" "J Liao" "J Goepp" "E Matthes" "SD Macknight" "D Rotin"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 1833




CID is 16760706 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/16760706

CID is 16760706
synonyms found at PubChem are:
88519-57-7, W-13 Hydrochloride, N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride, N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride, W-13, Hydrochloride, CHEBI:75367, IN1418, w-13, 2-Naphthalenesulfonamide,N-(4-aminobutyl)-5-chloro-, hydrochloride (1:1), N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide HCl, N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide, HCl, ACMC-209qtx, SCHEMBL1321464, CHEMBL1256657, CTK5G0044, DTXSID30587915, OR0200T, MolPort-003-844-471, QKAALLVQBOLELJ-UHFFFAOYSA-N, ZX-AT009382, ANW-39043, BS0212, AKOS024457714, VZ32932, KS-0000125F, CC-31447, DB-057079, TC-127788, B6276, FT-0629201, 519A577, C-20581, SR-01000597773, SR-01000597773-1, N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamideHydrochloride, N-(4-aminobutyl)-5-chloro-2-naphthalene sulfonamide hydro chloride, N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide--hydrogen chloride (1/1)