previous compound ID: 1862 next compound
InChIKey: QRXWMOHMRWLFEY-UHFFFAOYSA-N
SMILES: C1=CN=CC=C1C(=O)NN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53


Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"D Rotin" "SD Macknight" "E Matthes" "DY Thomas" "J Liao" "J Goepp" "JW Hanrahan" "R Robert" "GW Carlile" "B Kus"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 1862




CID is 3767 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/3767

CID is 3767
synonyms found at PubChem are:
isoniazid, Isonicotinic acid hydrazide, 54-85-3, Isonicotinohydrazide, Isoniazide, Rimifon, pyridine-4-carbohydrazide, Nydrazid, Isonicotinic hydrazide, Laniazid, Isonicotinylhydrazine, Andrazide, Cotinazin, Dinacrin, Hydrazid, Neoteben, Nicizina, Nicotibina, Nicozide, Pycazide, Tubazide, Ditubin, Iscotin, Isolyn, Isonex, Mybasan, Niconyl, Hyzyd, Isonicotinhydrazid, Antimicina, Atcotibine, Chemiazid, Hidranizil, Hidrasonil, Hydrazide, Isobicina, Isocidene, Isohydrazide, Isonicotan, Isonicotil, Isonidrin, Isonikazid, Isonindon, Isonizide, Isotebezid, Neumandin, Pyricidin, Pyrizidin, Stanozide, Armazid, Armazide, Cemidon, Chemidon, Defonin, Diforin, Ebidene, Ertuban, Eutizon, Fimalene, Hidrulta, Hycozid, Idrazil, Isidrina, Ismazide, Isocotin, Isonerit, Isonicid, Isonico, Isonide, Isonilex, Isonirit, Isoniton, Isozide, Niadrin, Nicetal, Nidaton, Nidrazid, Nikozid, Nitadon, Nyscozid, Pelazid, Raumanon, Retozide, Rimicid, Rimitsid, Tubazid, Azuren, Cedin, Eralon, Evalon, Hidrun, Inizid, Isocid, Isonin, Isozyd, Neoxin, Nevin, Niplen, Antituberkulosum, Inah, Ido-tebin, Bacillin, Isoniacid, Isotinyl, Nicazide, Nicotibine, Nicotisan, Phthisen, Pyreazid, Rimiphone, Tubilysin, Isotebe, Percin, Razide, Tyvid, Isoniazid SA, Neo-Tizide, GINK, Armacide, Cortinazine, Cotinizin, Isonicazide, Isotamine, Robisellin, Sauterazid, Teebaconin, Tibinide, Unicozyde, Vazadrine, Zonazide, Dibutin, Hyozid, Isonicotinoyl hydrazide, Tebecid, Tekazin, Tubeco, Tubicon, Tubomel, Vederon, Zinadon, Preparation 6424, Isonicotinyl hydrazide, TB-Razide, 4-Pyridinecarboxylic acid, hydrazide, Sanohidrazina, Tisiodrazida, Laniozid, Niteban, Pyridicin, Robiselin, Roxifen, Sauterzid, Tebenic, Tebexin, Tebilon, Tibazide, Tibison, Tibivis, Tibizide, Tibusan, Tuberian, Tubizid, Unicocyde, Tebos, Tisin, Tizide, Dow-Isoniazid, FSR 3, TB-Vis, Inh-Burgthal, TB-Phlogin, INH, Zidafimia, Isozid, Nitebannsc 9659, In-73, 4-Pyridinecarboxylic acid hydrazide, Cedin (Aerosol), RU-EF-Tb, bacillen, tebemid, tubercid, Isonicotinoylhydrazine, Continazine, Isoniazidum, Tubecotubercid, Abdizide, Anidrasona, Isoniazida, Isonizida, Tibemid, Tibiazide, Fetefu, Isokin, Hydra, BP 5015, FSR-3, Isonicotinsaeurehydrazid, 4-(Hydrazinocarbonyl)pyridine, 4-pyridinecarbohydrazide, 4-Pyridylcarbonylhydrazide, 4-Pyridinecarbonylhydrazine, LANIZID, NSC 9659, 4-Pyridinecarboxylic hydrazide, RY-EF-Tb, HIA, isoco tin, nidra zid, RP-5015, Hid rasonil, isozid e, rimif on, Isoniazidum [INN-Latin], Isoniazida [INN-Spanish], UNII-V83O1VOZ8L, FRS-3, AZT + Isoniazid, Laniazid (TN), C6H7N3O, CCRIS 351, Isonicotinylhydrazide, L 1945, isonicotinoylhydrazide, 5015 RP, Usaf cb-2, CHEBI:6030, Isonicotinyl hydrazine, isonicotinate hydrazide, 5015 R.P., HSDB 1647, Isonicotinsaeurehydrazid [German], INHd20, CHEMBL64, pyridine-4-carboxylic acid hydrazide, EINECS 200-214-6, RP 5015, I.A.I, V83O1VOZ8L, AI3-23936, Idrazide dell'acido isonicotinico [Italian], MLS000069444, I.A.I., bp 5 015, NSC9659, QRXWMOHMRWLFEY-UHFFFAOYSA-N, CAS-54-85-3, NCGC00016244-09, SMR000059082, DSSTox_CID_755, I0138, DSSTox_RID_75771, DSSTox_GSID_20755, SR-01000003025, Isoniazid [INN:BAN:JAN], Mayambutol, isoniazid (inh), Idrazide dell'acido isonicotinico, Isoniazid [USP:INN:BAN:JAN], isonicotinhydrazide, Isoniazid & EEP, Isoniazid(Tubizid), Nydrazid (TN), Soniazid,(S), NIZ, Prestwick_578, Isoniazid (Tubizid), Isoniazid & Propolis, Rifater (Salt/Mix), Isonicotinic acid hydrazide (Isoniazid), Spectrum_000853, ACMC-209ljq, Opera_ID_454, isonicotinicacid hydrazide, AC1L1GNZ, Prestwick0_000161, Prestwick1_000161, Prestwick2_000161, Prestwick3_000161, Spectrum2_000107, Spectrum3_000472, Spectrum4_000022, Spectrum5_000876, WLN: T6NJ DVMZ, isonicotinic acid hydrazone, SCHEMBL228, Biomol-NT_000288, D09XQF, Epitope ID:141801, 4-Pyridylcarbonyl hydrazide, AC1Q54UP, AC1Q54UQ, Oprea1_396155, BSPBio_000021, BSPBio_002204, Isoniazid daily for 9 months, KBioGR_000423, KBioSS_001333, MLS001055327, ARONIS25141, BIDD:GT0140, DivK1c_000070, SPECTRUM1500355, SPBio_000094, SPBio_001942, Isoniazid (JP17/USP/INN), BPBio1_000025, BPBio1_001322, SCHEMBL2998929, ZINC1590, component of Niadox (Salt/Mix), DTXSID8020755, HMS500D12, KBio1_000070, KBio2_001333, KBio2_003901, KBio2_006469, KBio3_001424, KS-00000JHE, MolPort-000-141-557, NINDS_000070, HMS1568B03, HMS1920H09, HMS2089I16, HMS2091N19, HMS2095B03, HMS2234G04, HMS3259E19, HMS3373O01, HMS3655L03, HMS3712B03, KUC109571N, Pharmakon1600-01500355, 4-pyridinecarbohydrazide(Isoniazid), BCP13791, HY-B0329, NSC-9659, STR00210, [(4-Pyridinylcarbonyl)oxy]hydrazine, Tox21_113640, Tox21_201367, Tox21_300193, ANW-32196, BBL008409, BDBM50336507, CCG-39710, LS-205, MFCD00006426, NSC757078, s1937, SBB004195, STK086288, AKOS000119062, Isonicotinic acid hydrazide(Isoniazid), Tox21_113640_1, CS-2371, DB00951, KSC-27-048, MCULE-6324947959, NC00513, NSC-757078, PS-4129, RP01120, RTR-019381, IDI1_000070, KS-0000471R, UPCMLD0ENAT5791176:001, NCGC00016244-01, NCGC00016244-02, NCGC00016244-03, NCGC00016244-04, NCGC00016244-05, NCGC00016244-06, NCGC00016244-07, NCGC00016244-08, NCGC00016244-10, NCGC00016244-11, NCGC00016244-12, NCGC00016244-14, NCGC00016244-15, NCGC00022648-03, NCGC00022648-04, NCGC00022648-05, NCGC00022648-06, NCGC00022648-07, NCGC00254094-01, NCGC00258919-01, 5015 R.P, AJ-08054, AN-24420, BC204682, CPD000059082, Isonicotinic acid hydrazide, 98% 100g, KB-52787, SAM002554904, SC-12623, ST078858, ZB000368, Isoniazid, Vetec(TM) reagent grade, 98%, SBI-0051419.P003, 4-Pyridinecarboxylic acid, hydrazide (9CI), AB1009474, KB-100175, TR-019381, AB00052025, BB 0240534, FT-0627424, ST24025094, T7976, ISONICOTINIC ACID HYDRAZIDE(ISONIAZIDE), C07054, D00346, Isoniazid, analytical standard, >=99% (TLC), 10319-EP2272972A1, 10319-EP2272973A1, 10319-EP2274983A1, 10319-EP2275102A1, 10319-EP2275401A1, 10319-EP2277872A1, 10319-EP2280000A1, 10319-EP2280012A2, 10319-EP2281563A1, 10319-EP2289510A1, 10319-EP2289876A1, 10319-EP2295407A1, 10319-EP2295411A1, 10319-EP2295416A2, 10319-EP2295433A2, 10319-EP2298312A1, 10319-EP2298736A1, 10319-EP2298747A1, 10319-EP2298748A2, 10319-EP2301536A1, 10319-EP2301538A1, 10319-EP2301924A1, 10319-EP2305640A2, 10319-EP2305642A2, 10319-EP2305808A1, 10319-EP2308852A1, 10319-EP2311455A1, 10319-EP2311824A1, 10319-EP2311830A1, 10319-EP2314584A1, 10319-EP2316452A1, 10319-EP2316459A1, 10319-EP2380872A1, 40687-EP2298761A1, 40687-EP2311830A1, AB00052025-20, AB00052025-21, AB00052025_22, AB00052025_23, AB00052025_24, AB00052025_25, 101033-EP2272832A1, 101033-EP2272972A1, 101033-EP2272973A1, 101033-EP2277872A1, 101033-EP2295053A1, 101033-EP2298776A1, 101033-EP2301544A1, AE-641/02310003, I14-9731, SR-01000003025-2, SR-01000003025-3, BRD-K87202646-001-26-8, Isoniazid, certified reference material, TraceCERT(R), Z58981801, F0391-0007, INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide, Isoniazid, European Pharmacopoeia (EP) Reference Standard, Isoniazid, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10, Isoniazid, Pharmaceutical??Secondary??Standard;??Certified??Reference??Material, 37271-10-6, 41466-07-3, 62229-51-0, 7640-37-1