previous compound ID: 19 next compound
InChIKey: RFDOKDAIYRJYJJ-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C=C(NN2)C3=CC=CC=C3)C(=O)C=C1

biological descriptors:

CFTR relevance: CFTR modulators

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 80
"P Negulescu" "JH Stack" "LR Makings" "PD Grootenhuis" "E Olson" "A Singh" "D Cao" "T Knapp" "R Tung" "S Hadida" "M Miller" "J González" "T Neuberger" "V Panchenko" "KS Straley" "A Hazlewood" "J Rader" "J Joubran" "F Van Goor"
ReferenceID: 2
"BT Conger" "SB Hicks" "D Skinner" "BA Woodworth" "EJ Sorscher" "SM Rowe" "S Zhang"
ReferenceID: 57
"CE Bear" "P Kim Chiaw" "LJ Huan" "M Ramjeesingh" "L Wellhauser"

chemical graph of compound 19




CID is 6742696
synonyms found at PubChem are:
VRT-532, VRT532, VRT 532, 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, Cambridge id 5478102, AC1OA052, GTPL4341, CTK8I5138, ZINC4576484, 4-methyl-6-(5-phenyl-1,2-dihydropyrazol-3-ylidene)cyclohexa-2,4-dien-1-one