previous compound ID: 2131 next compound
InChIKey: SSMIFVHARFVINF-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC3=C2C(=C1)C(=O)NC3=O)N

biological descriptors:

CFTR relevance: PARP-1 inhibitor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Nucleus (Transcription)

reference list:

ReferenceID: 53
"SD Macknight" "GW Carlile" "J Liao" "R Robert" "J Goepp" "D Rotin" "B Kus" "E Matthes" "DY Thomas" "JW Hanrahan"
ReferenceID: 82
"F Ciciriello" "GW Carlile" "J Liao" "H Balghi" "SM Anjos" "JW Hanrahan" "R Robert" "HM Sampson" "D Waller" "J Goepp" "F Dantzer" "DL Zhang" "P Ferraro" "P Lesimple" "DY Thomas" "R Phillipe"

chemical graph of compound 2131





CID is 1720
synonyms found at PubChem are:
4-Amino-1,8-naphthalimide, 1742-95-6, 4-Aminonaphthalimide, 6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE, 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione, 4-Aminonaphthalene-1,8-dicarboximide, Naphthalimide, 4-amino-, DFP 1, 1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino-, EINECS 217-110-1, 6-aminobenzo[de]isoquinoline-1,3-dione, BRN 0177185, PARP Inhibitor V, 4-ANI, CHEMBL338790, CHEBI:40071, SSMIFVHARFVINF-UHFFFAOYSA-N, 4-AMINO-1,8 NAPHTHALIMIDE, 6-Amino-1H-benz(de)isoquinoline-1,3(2H)-dione, 1H-Benz(de)isoquinoline-1,3(2H)-dione, 6-amino-, 4AN, 2pax, AC1Q6JKU, Lopac-A-0966, D03JTS, D09VUP, 4-ANI, Lopac0_000063, SCHEMBL21124, BSPBio_001430, KBioGR_000150, KBioSS_000150, 4-22-00-06603 (Beilstein Handbook Reference), AC1L1C36, ZINC8558, DTXSID6061941, BCBcMAP01_000231, BDBM27498, CTK8F5667, KBio2_000150, KBio2_002718, KBio2_005286, KBio3_000299, KBio3_000300, MolPort-002-499-717, Bio1_000370, Bio1_000859, Bio1_001348, Bio2_000150, Bio2_000630, HMS1361H12, HMS1791H12, HMS1989H12, HMS3260M07, HMS3402H12, BB_SC-07136, 4-Amino-1,8-naphthalimide, 96%, Tox21_500063, BBL027625, MFCD00006921, SBB003425, STK934866, AKOS005664748, AC-6718, CCG-204158, DB07096, LP00063, MCULE-5608953652, IDI1_033900, NCGC00015035-01, NCGC00015035-02, NCGC00015035-03, NCGC00015035-04, NCGC00015035-05, NCGC00015035-06, NCGC00015035-07, NCGC00093577-01, NCGC00093577-02, NCGC00093577-03, NCGC00093577-04, NCGC00093577-05, NCGC00260748-01, AJ-08314, AN-20710, AS-35824, CC-17680, LS-33496, ZB000667, AX8093535, A8840, EU-0100063, FT-0633814, ST50825610, A 0966, A-2606, 6-amino-1H-benz[de]-isoquinoline-1,3(2H)-dione, 7-Amino-3-hydroxy-1H-benzo[de]isoquinolin-1-one, C-30851, SR-01000075200, J-010976, SR-01000075200-1, 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione #, BRD-K50214219-001-02-4, I14-18437, 10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4-dione, 4-aminonaphthalene-1,8-dicarboxylic anhydride;6-Aminobenz[de]isochromene-1,3-dione