Galietta LJ et. al. 2001 (paper)
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.The Journal of biological chemistry, page 19723-8, volume 276, issue 23, year 2001
"MF Springsteel"
"MJ Haddadin"
"MH Nantz"
"M Eda"
"AS Verkman"
"LJ Galietta"
"K By"
"MJ Kurth"
"EJ Niedzinski"
DOI:
10.1074/jbc.M101892200 PMID:
11262417
Reference Into Function: Compounds of the 7,8-benzoflavone class, which are structurally intermediate between flavones and benzo[c]quinoliziniums, were effective CFTR activators with the most potent being 2-(4-pyridinium)benzo[h]4H-chromen-4-one bisulfate (UCcf-029). Compounds of the novel structural class of fused pyrazolo heterocycles were also strong CFTR activators with the most potent being 3-(3-butynyl)-5-methoxy-1-phenylpyrazole-4-carbaldehyde (UCcf-180).
CID is 205105 the link to PubChem record is
https://pubchem.ncbi.nlm.nih.gov/compound/205105
CID is
205105
synonyms found at PubChem are:
1,3-Diphenyl-4-formyl-2-pyrazolin-5-one, 17364-40-8, 2-Pyrazolin-5-one, 1,3-diphenyl-4-formyl-, 5-oxo-1,3-diphenyl-4H-pyrazole-4-carbaldehyde, AC1L4DYX, SCHEMBL17290527, LS-128870, 1,3-Diphenyl-5-oxo-2-pyrazoline-4-carbaldehyde, 5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazole-4-carbaldehyde
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