Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"R Robert"
"SD Macknight"
"DY Thomas"
"GW Carlile"
"JW Hanrahan"
"E Matthes"
"J Goepp"
"B Kus"
"D Rotin"
"J Liao"
DOI:
10.1016/j.jcf.2014.06.001 PMID:
24974227
Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.
CID is 6436473 the link to PubChem record is
https://pubchem.ncbi.nlm.nih.gov/compound/6436473
CID is
6436473
synonyms found at PubChem are:
Oxotremorine sesquifumarate salt, Oxotremorine fumarate (2:3), EINECS 241-388-3, 17360-35-9, 1-(N-(1-Pyrrolidinyl)-2-butynyl)-2-pyrrolidinone sesquifumarate, 1-(4-[1-Pyrrolidinyl]2-butynyl)-2-pyrrolidinone, 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate, 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, sesquifumarate, Bis(1-(4-(pyrrolidin-1-yl)but-2-ynyl)pyrrolidin-2-one) trifumarate, AC1O5LQH, CHEMBL1551988, oxotremorine ses-quifumarate salt, MolPort-006-122-212, HMS3262H10, HMS3266J20, Tox21_500914, MFCD00013163, AKOS024458667, tris(fumaric acid); bis(oxotremorine), CCG-222218, LP00914, 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, (E)-2-butenedioate (2:3), NCGC00094225-01, NCGC00261599-01, tris(butenedioic acid); bis(oxotremorine), LS-139011, EU-0100914, O 9126, Oxotremorine sesquifumarate salt, >=98% (HPLC), solid, 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, fumarate (2:3), 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, (E)-2-butenedioate (2:3) (9CI), 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, fumarate (2:3) (8CI)
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