previous compound ID: 2504 next compound
InChIKey: WRQBEFIJZLEUBS-NDENLUEZSA-N
SMILES: CC1=CC(=C(N1C2=CC=C(C=C2)OC)C)/C=C\3/C(=O)NC(=O)N(C3=O)CC4=CC=CO4

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"RK Guy" "T Ma" "LJ Galietta" "AS Verkman" "VS Gopinath" "N Pedemonte" "K Du" "C Folli" "GL Lukacs" "AA Shelat" "A Taddei" "H Yang"

chemical graph of compound 2504




CID is 1349528
synonyms found at PubChem are:
AC1LQF9X, SCHEMBL3113918, MolPort-002-194-707, HMS1586E02, ZINC15800021, SR-01000232745, SR-01000232745-1, (5Z)-1-(furan-2-ylmethyl)-5-[[1-(4-methoxyphenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-1,3-diazinane-2,4,6-trione