previous compound ID: 2804 next compound
InChIKey: ZFXYFBGIUFBOJW-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC=N2

biological descriptors:

CFTR relevance: Nonspecific phosphodiesterase inhibitor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 11
"KL Hamilton" "PC Chao"

chemical graph of compound 2804





CID is 2153
synonyms found at PubChem are:
theophylline, 58-55-9, 1,3-Dimethylxanthine, Elixophyllin, Theophyllin, Theolair, Nuelin, Theophylline anhydrous, Respbid, Theocin, Theo-dur, Elixophylline, Pseudotheophylline, Lanophyllin, Theovent, Uniphyl, Slo-phyllin, Accurbron, Armophylline, Bronkodyl, Doraphyllin, Liquophylline, Maphylline, Medaphyllin, Optiphyllin, Parkophyllin, Synophylate, Teofyllamin, Theacitin, Theocontin, Uniphyllin, Xantivent, Aerolate, Elixicon, Solosin, Teolair, Theobid, Theofol, Theograd, Theolix, Elixex, Acet-theocin, Slo-bid, Theophyl-225, Aerolate III, Duraphyl, Euphylong, Sustaire, Austyn, Somophyllin-t, Constant-T, Teofilina, Theochron, Xanthium, Asmax, Quibron T/SR, Theal tablets, Somophyllin-DF, Bronkodyl SR, Theoclair-SR, Theoclear LA, Spophyllin retard, Choledyl SA, Quibron-T, Theoclear 80, Aquaphyllin, Aerobin, Tefamin, Theo-11, Theodur, Theopek, Theospan, Theostat 80, Synophylate-L.A. Cenules, Theophylline, anhydrous, Theo-24, Theo-Dur-Sprinkle, LaBID, Cetraphylline, Chronophyllin, Diffumal, Duraphyllin, Elixomin, Etheophyl, Theolixir, Theophyl, Theophyline, Theostat, Theodel, Unifyl, LASMA, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, Elixophyllin SR, Theophylline-SR, Pro-vent, Somophyllin-CRT, Constant T, Aerolate SR, Theolair-SR, Theophyl-SR, 1,3-dimethyl-7H-purine-2,6-dione, Theona P, Uni-Dur, Theoclear-80, Quibron-T/SR, T-Phyl, Euphylline, Theoclear-200, Teofilina [Polish], Labophylline, Uniphylline, Afonilm, Bilordyl, Bronkotabs, Egifilin, Mudrane, Physpan, Pulmidur, Teonova, Theokin, Theonite, Asbron, Hylate, Afonilum Retard, Somophyllin T, Theo-Organidin, GS 2591A, Nuelin SA, 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione, Bronchodid Duracap, Theobid Jr., Theoclear L.A.-130, Uniphyllin continus, Quibron T-SR, Xanthine, 1,3-dimethyl-, Dimethylxanthine, NSC 2066, Teocen 200, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, X 115, Bronchoretard, Theo 24, Afonilum, Asmalix, Quadrinal, Respicur, Talotren, Teosona, Theoclear, Theodrip, Theoplus, Theotard, Unilong, Respid, Tesona, Pulmo-Timelets, Theobid Duracap, Elixophyllin(e), Somophyllin CRT, Quibron T, Theo-Nite, Theal tabl., Theodur Dry Syrup, Nuelin S.A, Telb-DS, Theo-DS, Theolair (TN), 1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, Bronchoparat, Elixophyllin (TN), Uniphyl (TN), Quibron-t (TN), SloPhyllin, SomophyllinT, UNII-0I55128JYK, ConstantT, Theodur G (TN), CCRIS 4729, Slo Phyllin, theo von ct, HSDB 3399, Theo Dur, Quibron TSR, ct, theo von, von ct, theo, Purine-2,6(1H,3H)-dione, 1,3-dimethyl-, Quibron T SR, EINECS 200-385-7, Nuelin S.A., CHEMBL190, Theo-24 (TN), Theo24, Theophylline [USP], C7H8N4O2, THEOBID JR, AI3-50216, MLS000069390, CHEBI:28177, ZFXYFBGIUFBOJW-UHFFFAOYSA-N, 0I55128JYK, 2,6-Dihydroxy-1,3-dimethylpurine, Euphyllin, 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine, 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, Theodur G, NCGC00018117-07, NCGC00018117-17, SMR000058537, DSSTox_CID_1336, 1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, Aminophylline dihydrate, DSSTox_RID_76090, DSSTox_GSID_21336, CAS-58-55-9, 111079-49-3, 75448-53-2, Theoconfin Continuous, Glycine Theophyllinate, 1,3 Dimethylxanthine, 1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione, SR-01000075195, throphylline, Telbans, Physpa, Telbans DrySyrup, Unicontin CR, 4eoh, Aescin-IIA, Telbans Dry Syrup, PubChem9695, Theophylline 454g, theophylline solu-tion, component of Primatene, Theophylline-[8-3H, Xanthine,3-dimethyl-, Opera_ID_76, Spectrum_001038, Theophylline (JP15), Theophylline (JP17), 2a3a, Theophylline aminoacetate, Theophylline (anhydrous), Prestwick0_000820, Prestwick0_000873, Prestwick1_000820, Prestwick1_000873, Prestwick2_000820, Prestwick2_000873, Prestwick3_000820, Prestwick3_000873, Spectrum2_000842, Spectrum3_000672, Spectrum4_000353, Spectrum5_001232, 8-(2-Furyl)theophylline, D0F8RA, UPCMLD-DP123, component of Theo-Organidin, EC 200-385-7, AC1L1D1F, SCHEMBL4915, Theophylline Anhydrous,(S), Theophylline Anhydrous, USP, Lopac0_000014, BSPBio_000719, BSPBio_000945, BSPBio_002363, component of Dicurin Procaine, GTPL413, KBioGR_000785, KBioSS_001518, 49746-06-7, KSC491S8L, MLS002152943, MLS002153487, MLS004491910, MLS006011970, ARONIS25346, BIDD:ER0557, BIDD:GT0151, DivK1c_000203, SPECTRUM1500568, SPBio_000823, SPBio_002640, SPBio_002866, BPBio1_000791, BPBio1_001041, SCHEMBL8312163, component of Tedral (Salt/Mix), DTXSID5021336, UPCMLD-DP123:001, BCBcMAP01_000071, BDBM10847, BDBM82053, component of Quibron (Salt/Mix), CTK3J1985, HMS500K05, KBio1_000203, KBio2_001518, KBio2_004086, KBio2_006654, KBio3_001583, NSC2066, component of Hecadrol (Salt/Mix), MolPort-001-002-058, MolPort-001-737-342, NINDS_000203, HMS1921E03, HMS2089A06, HMS2092M05, HMS2233E16, HMS3259O06, HMS3369N14, Pharmakon1600-01500568, component of Primatene (Salt/Mix), component of Bronkotabs (Salt/Mix), HY-B0809, NSC-2066, Theophylline 1.0 mg/ml in Methanol, Theophylline, >=99.0% (HPLC), Tox21_110827, Tox21_202375, Tox21_300028, BBL023514, CCG-20301, LS-241, MFCD00079619, NSC757346, PDSP1_001018, PDSP1_001234, PDSP2_001002, PDSP2_001218, STK397040, Theophylline (1,3-dimethylxanthine), ZINC18043251, AKOS000120961, AKOS005434016, component of Quibron Plus (Salt/Mix), Tox21_110827_1, component of Quibron-T/SR (Salt/Mix), component of Theo-organdin (Salt/Mix), component of Theolair plus (Salt/Mix), CS-4158, DB00277, MCULE-8236489917, NC00542, NE11194, NSC-757346, Purine-2,3H)-dione, 1,3-dimethyl-, RP24142, SDCCGMLS-0066620.P001, component of Theo-Organidin (Salt/Mix), IDI1_000203, KS-000010T0, KS-0000477R, SMP1_000291, component of Slo-phyllin GG (Salt/Mix), NCGC00018117-01, NCGC00018117-02, NCGC00018117-03, NCGC00018117-04, NCGC00018117-05, NCGC00018117-06, NCGC00018117-08, NCGC00018117-09, NCGC00018117-10, NCGC00018117-11, NCGC00018117-12, NCGC00018117-13, NCGC00018117-14, NCGC00018117-15, NCGC00018117-16, NCGC00018117-18, NCGC00018117-19, NCGC00018117-20, NCGC00018117-23, NCGC00022112-03, NCGC00022112-04, NCGC00022112-05, NCGC00022112-07, NCGC00022112-08, NCGC00022112-09, NCGC00022112-10, NCGC00022112-11, NCGC00022112-12, NCGC00254040-01, NCGC00259924-01, WLN: T56 BM DN FNVNVJ F1 H1, AC-20328, AN-23602, component of Dicurin Procaine (Salt/Mix), CPD000058537, NCI60_001736, SAM002554935, SC-05534, SC-95891, SMR003435989, ST024762, Theophylline, anhydrous, >=99%, powder, component of Primatene tablets (Salt/Mix), Purine,6(1H,3H)-dione, 1,3-dimethyl-, SBI-0050003.P004, AB1009249, component of Mudrane GG elixir (Salt/Mix), DB-053224, 1H-Purine-2, 3,7-dihydro-1,3-dimethyl-, AB00052106, FT-0631259, N1442, 1,3-dimethyl-1H-purine-2,6(3H,9H)-dione, 6461-EP1441224A2, 6461-EP2272835A1, 6461-EP2272841A1, 6461-EP2272844A1, 6461-EP2280006A1, 6461-EP2281813A1, 6461-EP2281815A1, 6461-EP2286811A1, 6461-EP2295434A2, 6461-EP2298305A1, 6461-EP2301933A1, 6461-EP2301936A1, 6461-EP2301937A1, 6461-EP2305219A1, 6461-EP2305640A2, 6461-EP2308562A2, 6461-EP2311827A1, 6461-EP2314590A1, C07130, D00371, 83377-EP2371823A1, AB00052106-20, AB00052106-22, AB00052106-23, AB00052106_24, AB00052106_25, AB00052106_26, 3,7-dihydro-1,3-dimethyl-1H- purine-2,6-dione, L000595, 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione #, Q-201819, SR-01000075195-1, SR-01000075195-3, SR-01000075195-5, 1,3-Dimethyl-6-hydroxy-1,3-dihydro-2H-purin-2-one, BRD-K97799481-001-02-0, BRD-K97799481-001-12-9, BRD-K97799481-002-03-6, I14-16783, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, mo, F2173-0145, Z271004650, A3133D49-AAB6-49A1-B60B-B5198F327D3F, Theophylline, British Pharmacopoeia (BP) Reference Standard, Theophylline, European Pharmacopoeia (EP) Reference Standard, (8alpha, 9S)-10,11-Dihydro-6'-methoxycinchonan-9-amine trihydrochloride, min. 90%, Theophylline melting point standard, United States Pharmacopeia (USP) Reference Standard, Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material, 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine; 1,3-Dimethylxanthine; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, 46157-00-0, 56645-32-0, InChI=1/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9, Theophylline melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material, Theophylline, certified reference material, United States Pharmacopeia (USP) Reference Standard