previous compound
ID: 2912
next compound
InChIKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
biological descriptors:
CFTR relevance: CFTR corrector, pocket 2
Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several
reference list:
ReferenceID: 85
"A Kupniewska"
"M Dadlez"
"M Ollero"
"P Zielenkiewicz"
"H Herrmann"
"A Roldan"
"EL Saussereau"
"K Tarnowski"
"G Wieczorek"
"F Becq"
"D Tondelier"
"N Servel"
"MF da Cunha"
"J Colas"
"L Wiszniewski"
"S Bitam"
"GL Lukacs"
"C Norez"
"N Odolczyk"
"J Fritsch"
"P Melin-Heschel"
"A Edelman"
"G Faure"
CID is 3151
synonyms found at PubChem are:
domperidone, 57808-66-9, Motilium, Nauzelin, Domperidonum, Domperidona, Domperidon, Motinorm, Costi, Domperidonum [INN-Latin], Domperidona [INN-Spanish], Motillium, R-33812, NSC299589, Motilium (TN), KW-5338, R 33,812, Domperidone (Motilium), Lopac-D-122, 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine, Domperidone [USAN:BAN:INN:JAN], Domperidone Maleate, EINECS 260-968-7, UNII-5587267Z69, KW 5338, BRN 0903774, 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone, MLS000069343, CHEMBL219916, CHEBI:31515, R-33,812, NCI299589, 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one, NSC-299589, HS-0067, D-122, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone, DSSTox_CID_25116, DSSTox_RID_80682, DSSTox_GSID_45116, 2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-, 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, W-105440, 5587267Z69, 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one, SMR000326802, CAS-57808-66-9, SR-01000003002, peridon, Nauzelin OD, Domperidone,(S), domperidone betadex, Motillium (TN), Motinorm (TN), 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-{1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, Domperidone [USAN:INN:BAN:JAN], Prestwick_794, Domperidone,Motilium, Costi (TN), PubChem15679, Spectrum_000391, Opera_ID_616, SpecPlus_000825, AC1L1FAB, Prestwick0_000461, Prestwick1_000461, Prestwick2_000461, Prestwick3_000461, Spectrum4_000087, domperidone betacyclodextrin, Biomol-NT_000022, D0AV3G, NCIStruc1_001686, NCIStruc2_001819, Lopac0_000427, SCHEMBL43729, BSPBio_002350, GTPL965, KBioGR_000354, KBioSS_000871, 5-24-02-00402 (Beilstein Handbook Reference), MLS000859942, MLS001306482, MLS002222324, DivK1c_006921, SPECTRUM2300212, SPBio_002501, Domperidone (JAN/USAN/INN), BPBio1_000620, BPBio1_001185, DTXSID1045116, CTK8B3352, Domperidone (JP17/USAN/INN), KBio1_001865, KBio2_000871, KBio2_003439, KBio2_006007, KS-00000PNZ, BBC/763, 99497-03-7 (maleate), FGXWKSZFVQUSTL-UHFFFAOYSA-N, MolPort-003-666-773, HMS1922N04, HMS2089C14, HMS2093N22, HMS2096C21, HMS2230N18, HMS3261E16, HMS3269O13, HMS3370L03, HMS3656M21, HMS3713C21, Pharmakon1600-02300212, BCP28265, Domperidone 1.0 mg/ml in Methanol, EBD46624, HY-B0411, ZINC4175569, ZX-AS004963, Tox21_110056, Tox21_500427, ANW-42358, BBL028136, BDBM50241107, BG0172, CCG-37870, CD0227, GP3849, MFCD00069256, NCGC00014670, NSC759575, s2461, STK622843, AKOS005555858, Tox21_110056_1, AC-2037, AN-5531, CS-2511, DB01184, Domperidone, powder, >=98% (HPLC), LP00427, MCULE-4430288884, NSC-759575, NCGC00014670-01, NCGC00014670-02, NCGC00014670-03, NCGC00014670-04, NCGC00014670-05, NCGC00014670-06, NCGC00014670-07, NCGC00014670-08, NCGC00014670-09, NCGC00014670-10, NCGC00014670-11, NCGC00014670-12, NCGC00014670-13, NCGC00014670-14, NCGC00014670-16, NCGC00014670-17, NCGC00015306-01, NCGC00021472-02, NCGC00021472-03, NCGC00021472-04, NCGC00021472-05, NCGC00021472-06, NCGC00021472-07, NCGC00021472-08, NCGC00097773-01, NCGC00261112-01, LS-33301, NCI60_002512, SC-18462, SMR000058969, 83898-65-1 (maleate (1:1)), AB0110085, AB1009278, AB00052423, D4125, EU-0100427, FT-0625588, D01745, AB00052423-06, AB00052423-07, AB00052423_08, AB00052423_09, 808D669, L000230, R 33812, I01-0054, SR-01000003002-2, SR-01000003002-4, SR-01000003002-7, BRD-K38305202-001-02-6, BRD-K38305202-001-08-3, I14-14161, Domperidone, European Pharmacopoeia (EP) Reference Standard, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one, 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]-4-piperidyl]-1H-benzimidazol-2-one, 2H-Benzimidazol-2-one,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-2H-1,2,4-triazol-3(4H)-one, 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]- 1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1- yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidine-4-yl]-1,3-dihydro-2H-benzimidazol-2-one;, 5-chloro-1-{1-[3(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-{1-[3-(1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one, 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone), DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
Loading…