previous compound ID: 2923 next compound
InChIKey: HEMNVSCJOZIBEQ-UHFFFAOYSA-N
SMILES: C1=CNC(=C1)C(=O)C2=C(C=CC(=C2)Cl)NC(=O)CN

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

ReferenceID: 85
"M Dadlez" "S Bitam" "K Tarnowski" "A Edelman" "C Norez" "L Wiszniewski" "P Melin-Heschel" "P Zielenkiewicz" "GL Lukacs" "A Roldan" "G Wieczorek" "G Faure" "J Fritsch" "D Tondelier" "J Colas" "N Odolczyk" "N Servel" "M Ollero" "EL Saussereau" "F Becq" "MF da Cunha" "H Herrmann" "A Kupniewska"

chemical graph of compound 2923





CID is 284708
synonyms found at PubChem are:
NSC140873, MLS000766105, 106410-13-3, NSC-140873, 2-amino-N-[4-chloro-2-(1H-pyrrole-2-carbonyl)phenyl]acetamide, Acetamide, 2-amino-N-[4-chloro-2-(1H-pyrrol-2-ylcarbonyl)phenyl]-, GCPK, 2-Amino-N-(4-chloro-2-(1H-pyrrole-2-carbonyl)phenyl)acetamide, ACMC-20ma4y, AC1L61GU, NCIStruc1_000814, NCIStruc2_000850, SCHEMBL9851289, CHEMBL1450586, CTK0D7247, ZINC21557, DTXSID00301064, HEMNVSCJOZIBEQ-UHFFFAOYSA-N, CCG-38259, NCGC00014365, NCI140873, AKOS030563283, NCGC00014365-02, NCGC00014365-03, NCGC00014365-04, NCGC00097473-01, NCI60_000895, SMR000528603, MLS000766105-02, MLS000766105-03, 2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, 2-amino-N-(4-chloro-2-(1H-pyrrol-2-ylcarbonyl)phenyl)acetamide