previous compound ID: 2926 next compound
InChIKey: HRCYEQFRHAXCRH-UHFFFAOYSA-N
SMILES: CN1C2=C(C=N1)C(=NC(=N2)NC3=CC(=CC=C3)Cl)NC4=CC(=CC=C4)Cl

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

ReferenceID: 85
"F Becq" "H Herrmann" "N Servel" "K Tarnowski" "M Ollero" "A Roldan" "S Bitam" "A Edelman" "J Colas" "EL Saussereau" "MF da Cunha" "M Dadlez" "N Odolczyk" "G Wieczorek" "D Tondelier" "J Fritsch" "A Kupniewska" "G Faure" "C Norez" "P Zielenkiewicz" "L Wiszniewski" "P Melin-Heschel" "GL Lukacs"

chemical graph of compound 2926




CID is 223753
synonyms found at PubChem are:
NSC11668, MLS000737956, NSC-11668, 4-N,6-N-bis(3-chlorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine, AC1L5CSO, NCIStruc1_001174, NCIStruc2_000793, cid_223753, CHEMBL1335220, SCHEMBL13100664, BDBM32629, MolPort-003-594-732, N4,4-d]pyrimidine-4,6-diamine, NCI11668, ZINC1718486, CCG-36888, NCGC00013125, AKOS024255121, MCULE-2217239478, NCGC00013125-02, NCGC00096246-01, NCI60_000381, SMR000528106, N4,N6-bis(3-chlorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine