previous compound ID: 2942 next compound
InChIKey: JSMKCCIMZBFWNW-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CC2=C(C=CC(=C2)NC3=C4C=C(C=CC4=[NH+]C5=C3C=CC(=C5)Cl)OC)O.[Cl-]

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

ReferenceID: 85
"P Melin-Heschel" "S Bitam" "GL Lukacs" "G Faure" "L Wiszniewski" "C Norez" "N Odolczyk" "J Colas" "A Kupniewska" "N Servel" "M Dadlez" "H Herrmann" "M Ollero" "EL Saussereau" "MF da Cunha" "F Becq" "K Tarnowski" "P Zielenkiewicz" "A Roldan" "G Wieczorek" "A Edelman" "D Tondelier" "J Fritsch"

chemical graph of compound 2942




CID is 5458251
synonyms found at PubChem are:
NSC130813, AC1NUQ41, DTXSID60419997, Phenol, 4-[(6-chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-, 4-[(6-chloro-2-methoxyacridin-10-ium-9-yl)amino]-2-[(4-methylpiperazin-1-yl)methyl]phenol chloride, CHEMBL1970271, 4-(6-chloro-2-methoxyacridin-9-ylamino)-2-((4-methylpiperazin-1-yl)methyl)phenol, dihydrochloride