previous compound ID: 2946 next compound
InChIKey: KBGSVTREQRCYHG-UHFFFAOYSA-N
SMILES: C2(=CC=C1C=C(C(=NC1=C2)N3CCN(CCC3)C(C4=CC=CS4)=O)C#N)C.CC

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 8
"MJ Kurth" "GL Lukacs" "AS Verkman" "B Yang" "AB Wood" "JM Knapp" "PW Phuan"

chemical graph of compound 2946