previous compound ID: 2977 next compound
InChIKey: NOGRVEQYQUCZIW-UHFFFAOYSA-N
SMILES: C2=C(C=C1C=C(C(=NC1=C2)N3CCN(CC3)C(C4=CC=CC=C4F)=O)C#N)OC.CC

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 8
"MJ Kurth" "B Yang" "PW Phuan" "AS Verkman" "GL Lukacs" "AB Wood" "JM Knapp"

chemical graph of compound 2977