previous compound ID: 3003 next compound
InChIKey: QVDYQHXNAQHIKH-TZIWHRDSSA-N
SMILES: c1cc(ccc1[C@H]2C[C@H](c3ccc(cc3O2)OC(F)F)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector, highly potent and efficacious

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3003




CID is 121301049
synonyms found at PubChem are:
J0IIT8QSQS, UNII-J0IIT8QSQS, ABBV-2222, Galicaftor, Galicaftor [INN], GLPG2222, SCHEMBL17708714, GLPG-2222, QVDYQHXNAQHIKH-TZIWHRDSSA-N, 1918143-53-9, 4-[(2R,4R)-4-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic acid, Benzoic acid, 4-((2R,4R)-4-(((1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl)carbonyl)amino)-7-(difluoromethoxy)-3,4-dihydro-2H-1-benzopyran-2-yl)-