previous compound ID: 3017 next compound
InChIKey: SLHLHESUSCADMP-UHFFFAOYSA-N
SMILES: C1C(C)CC(Br)C2NC3C(=O)CCCC=3C1=2

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"H Yang" "RK Guy" "T Ma" "C Folli" "AS Verkman" "A Taddei" "VS Gopinath" "K Du" "N Pedemonte" "LJ Galietta" "GL Lukacs" "AA Shelat"

chemical graph of compound 3017




CID is 85871990