previous compound ID: 324 next compound
InChIKey: CDSMSBUVCWHORP-UHFFFAOYSA-N
SMILES: CC(=C)C1CCC(=CC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53


Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"B Kus" "J Liao" "GW Carlile" "J Goepp" "SD Macknight" "DY Thomas" "E Matthes" "R Robert" "D Rotin" "JW Hanrahan"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 324




CID is 1256 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/1256

CID is 1256
synonyms found at PubChem are:
Perillic acid, (-)-perillic acid, 7694-45-3, 4-Isopropenylcyclohex-1-enecarboxylic acid, EINECS 231-709-5, CHEBI:36999, 4-Isopropenyl-1-cyclohexene-1-carboxylic acid, perillate, 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid, 1-Cyclohexene-1-carboxylic acid, 4-(1-methylethenyl)-, perillic acid(-), 4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, SR-01000076076, NSC 667676, NSC-667676, L(-)-Perillic acid, AC1Q5RCJ, 4-isopropenylcyclohex-1-ene carboxylic acid, AC1L1B2K, AC1Q1J4P, 4-(2-propenyl)-1-cyclohexane-1-carboxylic acid, Lopac0_001001, SCHEMBL465998, CHEMBL1373981, CTK2H9028, CDSMSBUVCWHORP-UHFFFAOYSA-N, HMS3263I03, Tox21_501001, FCH831661, NSC641067, AKOS006230667, CCG-205081, LMPR0102090041, LP01001, MCULE-2236994087, NSC-641067, NCGC00015832-02, NCGC00015832-03, NCGC00015832-04, NCGC00015832-05, NCGC00015832-06, NCGC00094295-01, NCGC00094295-02, NCGC00094295-03, NCGC00094295-04, NCGC00261686-01, LS-57451, NCI60_013759, EU-0101001, FT-0693829, C11924, P 7083, C-47095, SR-01000076076-1, SR-01000076076-5, SR-01000076076-6, 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-, 4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic acid, 1A4758DA-6365-4FD5-BAEA-16032D3488FF