previous compound ID: 504 next compound
InChIKey: DQQCJDBYNZMPOA-FFXKMJQXSA-N
SMILES: CN1CCC2=CC=CC3=C2[C@H]1CC4=C3C(=C(C=C4)O)O.O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53

Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"R Robert" "B Kus" "J Liao" "J Goepp" "DY Thomas" "D Rotin" "GW Carlile" "E Matthes" "JW Hanrahan" "SD Macknight"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 504



CID is 6852399 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/6852399

CID is 6852399
synonyms found at PubChem are:
R-(-)-Apomorphine, MLS000069811, Apomorphine hydrochloride hemihydrate, 41372-20-7, SMR000059235, R-(-)-Apomorphine hydrochloride hemihydrate, SMR000653528, (R)-Apomorphine Hydrochloride Hemihydrate, Opera_ID_1132, MLS001074112, MLS002153277, MLS002222153, C17H17NO2.ClH.H2O, SCHEMBL5429071, CHEMBL1256708, HW2A207, 2223AH, AKOS030526144, NCGC00180984-01, SMR001307246, R(-) Apomorphine hydrochloride hemihydrate, MLS-0235817.0001, (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride hydrate