previous compound ID: 730 next compound
InChIKey: GLMUPSMDHQHUED-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"RK Guy" "AA Shelat" "GL Lukacs" "A Taddei" "VS Gopinath" "C Folli" "T Ma" "K Du" "LJ Galietta" "AS Verkman" "H Yang" "N Pedemonte"

chemical graph of compound 730





CID is 722862
synonyms found at PubChem are:
CHEMBL209937, 2-[(2-methylbenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, AC1LF4HZ, Oprea1_406206, Oprea1_857326, ARONIS018977, SCHEMBL5453093, MolPort-000-999-154, ZINC127333, BDBM50185106, STK007957, AKOS000291770, MCULE-9702864044, KS-00004B19, BAS 00803292, ST015560, BB0274140, EU-0068219, SR-01000401029, SR-01000401029-1, 2-(2-methylbenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, 2-[(2-methylphenyl)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbox amide, 2-{[(2-methylphenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide