previous compound ID: 75 next compound
InChIKey: VPJJUDAXEIWYQR-UHFFFAOYSA-N
SMILES: C1CCCC2SC(NC(=O)C3=CC=CC=C3Cl)=C(C(=O)N)C1=2

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"H Yang" "VS Gopinath" "K Du" "C Folli" "N Pedemonte" "AS Verkman" "T Ma" "RK Guy" "AA Shelat" "LJ Galietta" "A Taddei" "GL Lukacs"

chemical graph of compound 75





CID is 723141
synonyms found at PubChem are:
CHEMBL210832, 2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, 298193-32-5, 2-[(2-chlorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, BAS 00568157, CBMicro_048310, dF508act-02, AC1LF54M, AC1Q4Z7D, Cambridge id 5367707, Oprea1_211305, Oprea1_265080, SCHEMBL3110880, MolPort-000-224-232, VPJJUDAXEIWYQR-UHFFFAOYSA-N, ZINC127920, BDBM50185114, STL282684, AKOS000291649, MCULE-3529042180, ACM298193325, KB-13984, BIM-0048269.P001, KB-113545, EU-0035371, ST50003514, SR-01000404669, SR-01000404669-1, F0016-0638, 2-(2-Chlorobenzoylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acidamide, 2-[(2-chlorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxamide, 2-[(2-chlorophenyl)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbox amide, 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-C-(2-chlorobenzene)-4,5,6,7-tetrahydro-1-benzothiophene-2,3-dicarboxamide