previous compound ID: 81 next compound
InChIKey: XSDQTOBWRPYKKA-UHFFFAOYSA-N
SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N

biological descriptors:

CFTR relevance: induces depolarization

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 74
"D Salinas" "Y Song" "LJ Galietta" "N Pedemonte" "L Qian" "ND Sonawane" "AS Verkman"
ReferenceID: 31
"A Mengos" "AM Van Heeckeren" "BR Grubb" "RC Boucher" "JR Riordan" "ML Drumm" "MR Knowles" "M Gentzsch" "SE Gabriel" "SH Randell"

chemical graph of compound 81




CID is 16231
synonyms found at PubChem are:
AMILORIDE, Amipramidin, Midamor, 2609-46-3, Guanamprazine, Amilorida, Amipramizid, Amipramizide, Guanamprazin, Amiloridum, Amyloride, Amiloridum [INN-Latin], Amilorida [INN-Spanish], Amiloride HCL, Amiloride [INN:BAN], N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide, 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, Amiprazidine, C6H8ClN7O, UNII-7DZO8EB0Z3, Amiclaran (TN), Amiloride (INN), CCRIS 6545, EINECS 220-024-7, N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid, Amiloride hydrochloride hydrate, CHEMBL945, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, 7DZO8EB0Z3, CHEBI:2639, 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide, Amikal (Hydrochloride dihydrate), Midamor (Hydrochloride dihydrate), XSDQTOBWRPYKKA-UHFFFAOYSA-N, 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide, MK-870 (Hydrochloride dihydrate), N-amidino-3,5-diamino-6-chloro-2-pyrazinecarboxamide, NCGC00015089-08, AMIPRAMIDINE, DSSTox_CID_23853, DSSTox_RID_80077, Amiloride Hydrocholride, DSSTox_GSID_43853, AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8)), 3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, 137053-86-2, CAS-2609-46-3, Amiclaran, Amilorid, (3,5-diamino-6-chloropyrazin-2-yl)-N-(???methyl)carboxamide, Biduret (TN), Spectrum_000034, Tocris-0890, 1f5l, AC1Q3POC, Prestwick0_000007, Prestwick1_000007, Prestwick2_000007, Prestwick3_000007, Spectrum2_000118, Spectrum3_000293, Spectrum4_000132, Spectrum5_000776, Lopac-A-7410, D0I0RJ, AC1L27IZ, Lopac0_000111, SCHEMBL27562, BSPBio_000013, BSPBio_001572, BSPBio_001826, KBioGR_000292, KBioGR_000544, KBioSS_000292, KBioSS_000394, MLS001060798, BIDD:GT0466, DivK1c_000182, SPBio_000136, SPBio_001934, BPBio1_000015, GTPL2421, DTXSID9043853, BCBcMAP01_000101, BDBM16173, KBio1_000182, KBio2_000292, KBio2_000394, KBio2_002860, KBio2_002962, KBio2_005428, KBio2_005530, KBio3_000583, KBio3_000584, KBio3_001326, Amiloride (Na-Ca chanel blocker), MolPort-005-934-472, NINDS_000182, 17440-83-4 (hydrochloride), Bio1_000359, Bio1_000848, Bio1_001337, Bio2_000292, Bio2_000772, HMS1791O14, HMS1989O14, HMS2089H05, HMS2213E05, HMS3355K04, ACT05635, ACT05652, BCP16815, HY-B0285, ZINC4340269, Tox21_110080, BBL028157, SBB037856, STL373007, AKOS015961348, Tox21_110080_1, API0000380, CCG-204206, CS-2297, DB00594, LS-1094, MCULE-5948863568, 2016-88-8 (anhydrous hydrochloride), IDI1_000182, IDI1_034042, NCGC00015089-01, NCGC00015089-02, NCGC00015089-03, NCGC00015089-04, NCGC00015089-05, NCGC00015089-06, NCGC00015089-07, NCGC00015089-09, NCGC00015089-11, NCGC00015089-12, NCGC00015089-13, NCGC00015089-14, NCGC00015089-15, NCGC00015089-16, NCGC00015089-17, NCGC00024443-02, NCGC00024443-05, NCGC00024443-06, NCGC00024443-07, NCGC00024443-09, AC-13631, SMR000486264, ST079279, U460, (3,5-Diamino-6-chloropyrazinoyl)guanidine, SBI-0050099.P004, N-amidino-3,5-diamino-6-chloropyrazinamide, AB00053415, FT-0703177, C06821, D07447, EN300-149459, AB00053415-24, AB00053415-25, AB00053415_26, AB00053415_27, AB00053415_28, 117188-EP2277879A1, 117188-EP2298776A1, 609A463, J-016249, BRD-K97181089-003-02-3, BRD-K97181089-310-03-0, N-amidino 3,5-diamino-6-chloro-2-pyrazinecarboxamide, F2173-0531, 3,5-diamino-N-carbamimidoyl-6-chloro-pyrazine-2-carboxamide, 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride