previous compound ID: 899 next compound
InChIKey: HXTDAUGEZTYMGP-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=O)O2)C=C1N=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53

Carlile GW et. al. 2015 (paper)
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, page 16-25, volume 14, issue 1, year 2015
"D Rotin" "SD Macknight" "E Matthes" "GW Carlile" "R Robert" "DY Thomas" "J Goepp" "JW Hanrahan" "B Kus" "J Liao"
DOI: 10.1016/j.jcf.2014.06.001
PMID: 24974227


Reference Into Function: These studies show that ibuprofen is a CFTR corrector and that it causes correction by COX-1 inhibition.


chemical graph of compound 899



CID is 1871 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/1871

CID is 1871
synonyms found at PubChem are:
6-Nitroso-1,2-benzopyrone, 6-Nitrosocoumarin, 130506-22-8, 6-nitrosochromen-2-one, 2H-1-Benzopyran-2-one, 6-nitroso-, 2H-1-Benzopyran-2-one,6-nitroso-, 6-NO2BP, NOBP, ACMC-20dbyy, Lopac-N-8403, AC1L1CF3, AC1Q6R3N, Lopac0_000869, 6-nitroso-2H-chromen-2-one, SCHEMBL792923, CHEMBL1255659, CTK4B6758, DTXSID90156580, HMS3262N19, ZINC3871211, Tox21_500869, AKOS006271903, CCG-204951, LP00869, NCGC00015753-01, NCGC00015753-02, NCGC00015753-03, NCGC00015753-04, NCGC00094193-01, NCGC00094193-02, NCGC00261554-01, AJ-46342, RT-010698, EU-0100869, N 8403, SR-01000076033, J-005818, SR-01000076033-1, 6-Nitroso-1,2-benzopyrone, ADP-ribosyltransferase inhibitor