previous compound ID: 911 next compound
InChIKey: HZYRBUCNWBHBKG-UHFFFAOYSA-N
SMILES: C1CCC2=C(C1)C(=C(S2)NC(=O)NC3=CC=CC=C3)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 14
"RK Guy" "GL Lukacs" "C Folli" "A Taddei" "N Pedemonte" "AS Verkman" "LJ Galietta" "T Ma" "VS Gopinath" "H Yang" "K Du" "AA Shelat"

chemical graph of compound 911




CID is 730612
synonyms found at PubChem are:
2-[(anilinocarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-[(phenylcarbamoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, BAS 02283611, AC1LE5JX, Cambridge id 6284183, TimTec1_003014, Oprea1_332571, Oprea1_467201, ARONIS021903, SCHEMBL5450860, HZYRBUCNWBHBKG-UHFFFAOYSA-N, MolPort-000-884-421, HMS1542I22, ZINC143445, KS-00004D9Z, STK008802, AKOS000281732, MCULE-6024236949, ST040702, BB0276176, KB-122439, AN-329/40173696, BRD-K65277491-001-01-5, Z44613029, 2-(N'-Phenylureido)-4,5,6,7-tetrahydro-benzo[b]thiophen-3-carbonsaureamid, 2-(phenylcarbamoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-[(anilinocarbonyl)amino]-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxamide, 2-[(phenylamino)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxami de, 27285-13-8