Galietta LJ et. al. 2001 (paper)
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.The Journal of biological chemistry, page 19723-8, volume 276, issue 23, year 2001
"M Eda"
"K By"
"LJ Galietta"
"MF Springsteel"
"MH Nantz"
"EJ Niedzinski"
"MJ Kurth"
"MJ Haddadin"
"AS Verkman"
DOI:
10.1074/jbc.M101892200 PMID:
11262417
Reference Into Function: Compounds of the 7,8-benzoflavone class, which are structurally intermediate between flavones and benzo[c]quinoliziniums, were effective CFTR activators with the most potent being 2-(4-pyridinium)benzo[h]4H-chromen-4-one bisulfate (UCcf-029). Compounds of the novel structural class of fused pyrazolo heterocycles were also strong CFTR activators with the most potent being 3-(3-butynyl)-5-methoxy-1-phenylpyrazole-4-carbaldehyde (UCcf-180).
CID is 9611398 the link to PubChem record is
https://pubchem.ncbi.nlm.nih.gov/compound/9611398
CID is
9611398
synonyms found at PubChem are:
ethyl 3-[(anilinocarbonyl)hydrazono]butanoate, MLS000702358, ARONIS019401, CHEMBL3194047, MolPort-001-023-914, MolPort-009-658-029, STK051697, AKOS000486567, SMR000228653, BB0274322, AN-329/40239167, ethyl (3E)-3-[2-(phenylcarbamoyl)hydrazinylidene]butanoate
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