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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"Y Seo" "W Namkung" "J Park" "PK Sharma" "DK Jeon" "S Kumar" "HK Lee" "S Jo" "P Khloya"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=18
ID: 2874
InChIKey: ACMPJJXJGXDZQQ-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2874



ID: 2892
InChIKey: CJFNUDMDMGMQSU-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2892



ID: 2933
InChIKey: IOEFAGPRYUOIGM-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC(C)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2933



ID: 2922
InChIKey: GYKFXFYRHJPFGH-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2922



ID: 2968
InChIKey: MGASRLPRYQFEOV-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2968



ID: 2979
InChIKey: NTGHLTJGUCFIPS-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC(C)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2979



ID: 3065
InChIKey: YWPPDWBQKYEYCU-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 3065



ID: 2935
InChIKey: ISSNGBUFJXTJKY-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC=C2O)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2935



ID: 2960
InChIKey: LJBFRHUDVJSADK-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2960



ID: 2882
InChIKey: BFBZAASQFWNNIU-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC=C2OC)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2882



ID: 3010
InChIKey: RTBMADYWNFZUHP-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC=C2OC)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3010



ID: 3018
InChIKey: SPJAGELQBZMCPJ-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC=C2O)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3018



ID: 3057
InChIKey: XGJKADGASPPCCX-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 3057



ID: 2916
InChIKey: GALYZWCGYCEXNA-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 2916



ID: 3060
InChIKey: XOQDICYZWFFYGC-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC(C)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3060



ID: 3025
InChIKey: UNOWBPZMWCFSSM-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC=C2OC)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3025



ID: 3053
InChIKey: WVGUWJOVXKGXTK-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC=C2O)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 3053



ID: 2978
InChIKey: NRWHTHBUNDPHEF-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2978