ID: 42
InChIKey: JIMHYXZZCWVCMI-RIYZIHGNSA-N SMILES: C1=CC(=CC(=C1)N2C(=O)/C(=C\C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F
biological descriptors:
CFTR relevance: CFTR inhibitorCategory:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 1554210
synonyms found at PubChem are:
CFTR Inhibitor 172, C18H10F3NO3S2, 307510-92-5, CFTRinh 172, CFTR(inh)-172, 4-[(E)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid, CFTRinh-172, CFTRinh - 172, AC1LT95D, CFTR-172, SCHEMBL1881897, CHEMBL1554655, 5-[(4-Carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl-4-thiazolidinone, 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone, MolPort-008-130-993, MolPort-028-751-092, 4-[4-oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-(5z)-ylidenemethyl]-benzoic acid, 4-[4-OXO-2-THIOXO-3-(3-TRIFLUOROMETHYL-PHENYL)-THIAZOLIDIN-5-YLIDENEMETHYL]-BENZOIC ACID, 2313AH, s7139, ZINC13829351, AKOS003140113, NCGC00165765-01, KB-41399, BB0220685, BB 0220685, CFTR(inh)-172, >=98% (HPLC), powder, 4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid, 4-{[(5E)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl}benzoic acid, benzoic acid, 4-[[4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]-
ID: 59
InChIKey: OLOOJGVNMBJLLR-UHFFFAOYSA-N SMILES: CC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 10212
synonyms found at PubChem are:
IMPERATORIN, 482-44-0, Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene, Marmelide, NSC 402949, CCRIS 4346, UNII-K713N25C78, 9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one, HSDB 3497, EINECS 207-581-1, 9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one, AI3-61725, CHEBI:5885, CHEMBL453805, OLOOJGVNMBJLLR-UHFFFAOYSA-N, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-, 9-(3-Methylbut-2-enyloxy)furo[3,2-g]chromen-7-one, K713N25C78, 9-(3-Methylbut-2-enyloxy)-7H-furo(3,2-g)chromen-7-one, NCGC00095209-01, 9-((3-Methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one, 9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one, 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-, 6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone, 9-[(3-METHYL-2-BUTEN-1-YL)OXY]-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE, 5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, delta-lactone, DSSTox_CID_28663, DSSTox_RID_82933, DSSTox_GSID_48737, Q-100532, 9-(3-methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one, 9-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one, 9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]-1-benzopyran-7-one, CAS-482-44-0, Pentosalen [BAN], Enoxypsoralen, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-, Pentasalen, BAN, Imperatorin,(S), 8-Prenyloxypsoralen, Spectrum_000755, 8-isopentenyloxypsoralen, 5-hydroxy-8-(1,1-dimethylallyl)psoralen, SpecPlus_000755, AC1L1UPZ, Spectrum2_000376, Spectrum3_000145, Spectrum4_001422, Spectrum5_000244, [3,2-g]chromen-7-one, D09ROW, Oprea1_407817, SCHEMBL50437, BSPBio_001850, KBioGR_001864, KBioSS_001235, SPECTRUM102076, MLS000574838, DivK1c_006851, SPBio_000531, Marmelosin, analytical standard, MEGxp0_000089, ZINC1904, DTXSID8048737, ACon1_001117, CTK5J8942, KBio1_001795, KBio2_001235, KBio2_003803, KBio2_006371, KBio3_001050, MolPort-000-881-264, HMS1922N22, HMS2218G08, HMS3261C08, HMS3354E04, BCP28280, HY-N0285, 8-(3-Methyl-2-butenyloxy)psoralen, Tox21_113179, Tox21_500413, BDBM50308719, CCG-38649, CI0030, MFCD00016881, NSC402949, 9-(3-methylbut-2-enyloxy)-7H-furo, AKOS000277029, Tox21_113179_1, AC-8046, AN-8400, API0002987, CS-5800, Imperatorin, >=98% (HPLC), powder, LP00413, MCULE-3248623364, NSC-402949, SDCCGMLS-0066373.P001, NCGC00095209-02, NCGC00095209-03, NCGC00095209-04, NCGC00095209-05, NCGC00095209-06, NCGC00169661-01, NCGC00169661-02, NCGC00261098-01, CC-29497, LS-70737, SC-16643, SMR000156241, ZB000436, TR-036857, WLN: T C566 DO LVOTJ BO2UY1&1, FT-0603414, I0904, N1859, ST45000841, W1274, 7H-Furo[3, 9-[(3-methyl-2-butenyl)oxy]-, C09269, 482I440, A827504, C-16983, SR-01000721772, I06-0320, SR-01000721772-2, 9-(3-Methyl-2-butenyloxy)-7-oxofuro[3,2-g]chromene, 9-(3-methylbut-2-enyloxy)furano[3,2-g]chromen-2-one, 9-(3-methylbut-2-enoxy)-7-furo[3,2-g][1]benzopyranone, Imperatorin, European Pharmacopoeia (EP) Reference Standard, 9-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one #, 9-[(3-methylbut-2-en-1-yl)oxy]-2H-furo[3,2-g]chromen-2-one, 9-[(3-Methylbut-2-enyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, (9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one), 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one,9-[(3-methyl-2-buten-1-yl)oxy]-, 9-[(3-Methyl-2-butenyl)-oxy]-7H-furo[3,2-g][1][benzopyran-7-one, 9-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9CI, 5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, .delta.-lactone, 70102-00-0, InChI=1/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H
ID: 2578
InChIKey: XGPBRZDOJDLKOT-NXIDYTHLSA-N SMILES: C/C=C(/C)\C(=O)O[C@H]1[C@H](C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 38347607
synonyms found at PubChem are:
Praeruptorin A, 73069-27-9, (+)-Praeruptorin A, 73069-25-7, (-)-Praeruptorin A, PraeruptorinA, CHEMBL2376509, DTXSID20653395, MolPort-020-005-726, ZINC31156206, AKOS016011014, AJ-84194, AK119810, AX8245226, (9S,10S)-10-(Acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl (2Z)-2-methylbut-2-enoate, [(9S,10S)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate
ID: 48
InChIKey: MBRLOUHOWLUMFF-UHFFFAOYSA-N SMILES: CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 10228
synonyms found at PubChem are:
Osthole, Osthol, 484-12-8, Ostol, Ostole, 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one, 7-Methoxy-8-isopentenylcoumarin, 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-, 8-(3-Methyl-2-butenyl)herniarin, 7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one, 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, UNII-XH1TI1759C, NSC 31868, 7-METHOXY-8-(3-METHYL-2-BUTENYL)-COUMARIN, 7-methoxy-8-(3-methyl-2-butenyl)coumarin, Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-, CHEMBL52229, XH1TI1759C, CHEBI:69832, C15H16O3, NSC31868, 7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one, Q-100535, 7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one, SMR000156202, Osthole (Osthol), Osthole,(S), Cnidium Fruit Extract, Spectrum_001542, SpecPlus_000946, Spectrum2_000723, Spectrum3_001645, Spectrum4_001687, Spectrum5_000334, AC1L1UR5, Osthole, analytical standard, Oprea1_642606, Oprea1_873803, SCHEMBL50436, BSPBio_003369, KBioGR_001954, KBioSS_002022, ZINC566, MLS000574904, MLS001048988, MLS006011425, DivK1c_007042, SPECTRUM1504165, SPBio_000646, MEGxp0_000155, ACon1_002155, CTK7A8592, KBio1_001986, KBio2_002022, KBio2_004590, KBio2_007158, KBio3_002589, DTXSID20197507, MBRLOUHOWLUMFF-UHFFFAOYSA-N, MolPort-000-881-851, HMS2267O21, HMS3656A07, BCP10832, EBD33224, HY-N0054, KS-00000N3A, ANW-50075, BBL013019, BDBM50240512, CCG-40172, CO0040, MFCD00076049, NSC-31868, s2337, STK396321, AKOS000277663, AC-8041, AN-8395, CS-2125, DS-0881, MCULE-5691054147, RP28651, RTR-017689, SDCCGMLS-0066780.P001, NCGC00095694-01, NCGC00095694-02, NCGC00095694-03, NCGC00095694-05, WLN: T66 BOVJ IO1 J2UY1&1, 4CN-0704, AJ-07908, AK-35300, BAS 00015470, BR-35300, CC-33366, CJ-00015, LS-55250, ZB000125, AB0021820, AX8007596, KB-250032, ST2412572, TR-017689, FT-0082540, FT-0601535, N1825, O0426, ST50909221, W1256, C09280, J10077, S-3211, 484O128, A827530, C-14815, Osthole, primary pharmaceutical reference standard, SR-01000721624, I06-0435, SR-01000721624-4, BRD-K78294846-001-03-3, 7-Methoxy-8-(3-methyl-2-butenyl)-2H-chromen-2-one #, 7-methoxy-8-(3-methylbut-2-enyl)-1-benzopyran-2-one, Osthole, European Pharmacopoeia (EP) Reference Standard, 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- (9CI), 1440642-68-1, InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H
ID: 69
InChIKey: RODXRVNMMDRFIK-UHFFFAOYSA-N SMILES: COC1=C(C=C2C(=C1)C=CC(=O)O2)O
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 5280460
synonyms found at PubChem are:
scopoletin, 92-61-5, Gelseminic acid, 6-Methylesculetin, 7-Hydroxy-6-methoxy-2H-chromen-2-one, Chrysatropic acid, Scopoletine, 7-Hydroxy-6-methoxycoumarin, Murrayetin, Scopoletol, 6-O-Methylesculetin, Escopoletin, 6-Methoxy-7-hydroxycoumarin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, 6-Methoxyumbelliferone, 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-, Esculetin 6-methyl ether, beta-Methylesculetin, Esculetin-6-methyl ether, .beta.-Methylesculetin, Buxuletin, UNII-KLF1HS0SXJ, COUMARIN, 7-HYDROXY-6-METHOXY-, 7-hydroxy-6-methoxychromen-2-one, 7-Hydroxy-5-methoxycoumarin, NSC 405647, CCRIS 3592, KLF1HS0SXJ, EINECS 202-171-9, NSC405647, BRN 0156296, CHEMBL71851, CHEBI:17488, RODXRVNMMDRFIK-UHFFFAOYSA-N, 7-hydroxy-6-methoxy-chromen-2-one, TNP00096, NSC-405647, S-2000, 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy- (9CI), Chrysotropic Acid, Acid, Gelseminic, Scopoletin solution, 100 mM in DMSO, Acid, Chrysotropic, SMR000112541, 92-61-5 solution, 100 mM in DMSO, Gelseminic acid solution, 100 mM in DMSO, 6-Methylesculetin solution, 100 mM in DMSO, SR-01000841273, Baogongteng B, b-Methylaesculetin, beta -methylesculetin, PubChem15777, Scopoletin, >=99%, Prestwick0_000962, Prestwick1_000962, Prestwick2_000962, Prestwick3_000962, Spectrum2_001207, Spectrum3_001532, Spectrum4_001054, Spectrum5_000654, Aesculetin 6-methyl ether, D05QOR, AC1NQX27, BIDD:PXR0125, BSPBio_000963, BSPBio_002944, KBioGR_001348, 5-18-03-00203 (Beilstein Handbook Reference), 7-hydroxy-6-methoxy-coumarin, MLS002154074, MLS002472878, DivK1c_000720, SCHEMBL147702, SPECTRUM1502242, 7-hydroxy 6-methoxy coumarine, SPBio_000994, SPBio_002884, Scopoletin, analytical standard, BPBio1_001061, MEGxp0_001192, DTXSID0075368, ACon1_000143, HMS502D22, KBio1_000720, KBio3_002444, KS-00000YGS, ZINC57733, BIS1402, MolPort-000-707-493, NINDS_000720, ZX-AFC000681, HMS1571A05, HMS1921N16, HMS2098A05, HMS2268G04, ALBB-023369, BCP13342, HY-N0342, ZX-AN021883, ZX-AT021192, 6-methoxy-7-oxidanyl-chromen-2-one, BDBM50156693, CCG-39140, MFCD00006872, TD8126, Scopoletin solution, 20 mM in DMSO, AKOS000277133, CS-5791, FCH1115349, MCULE-6077230919, OR22352, RTR-029034, CAS-92-61-5, IDI1_000720, 7-hydroxy-6-methoxy-1-benzopyran-2-one, 92-61-5 solution, 20 mM in DMSO, NCGC00016349-01, NCGC00016349-02, NCGC00016349-03, NCGC00016349-04, NCGC00016349-05, NCGC00016349-06, NCGC00016349-07, NCGC00016349-08, NCGC00094973-01, NCGC00094973-02, NCGC00094973-03, 4CN-0905, AJ-09778, AK111291, AN-42608, CC-34387, LS-55217, NCI60_003834, SC-90283, ST056287, ZB002243, 7-Hydroxy-6-methoxy-2H-chromen-2-one #, Gelseminic acid solution, 20 mM in DMSO, AB0019688, AX8035441, KB-249948, TR-029034, 6-Methylesculetin solution, 20 mM in DMSO, AB00443525, FT-0631451, S0367, ST24045669, C01752, W-3522, 006S872, A844290, C-30831, SR-01000841273-3, SR-01000841273-4, 7-hydroxy-6-methoxycoumarin solution, 20 mM in DMSO, BRD-K96163925-001-06-5, BRD-K96163925-001-09-9, I14-14171, 0B4B9FAA-686D-4977-AA08-65F8E4F1977C, 7-hydroxy-6-methoxychromen-2-one solution, 20 mM in DMSO, Scopoletin, United States Pharmacopeia (USP) Reference Standard
ID: 2560
InChIKey: XDROKJSWHURZGO-UHFFFAOYSA-N SMILES: C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3
biological descriptors:
CFTR relevance: CFTR correctorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 10658
synonyms found at PubChem are:
Angelicin, ISOPSORALEN, 523-50-2, 2H-Furo[2,3-H]chromen-2-one, Angecin, furo[2,3-h]chromen-2-one, Isopsoralin, Furo(2,3-h)coumarin, Angelecin, Angelicin (coumarin derivative), 2H-Furo[2,3-H]-1-benzopyran-2-one, 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran, UNII-CZZ080D7BD, Angelicin (coumarin deriv), NSC 404563, CCRIS 4276, Furo(5',4':7,8)coumarin, HSDB 3554, 4-Hydroxy-5-benzofuranacrylic acid gamma-lactone, BRN 0153970, CZZ080D7BD, 2H-Furo(2,3-H)-1-benzopyran-2-one, CHEMBL53569, Furo[5',4':7,8]coumarin, 3-(4-Hydroxy-5-benzofuranyl)-2-propenoic acid gamma-lactone, CHEBI:28928, 2H-Furo(2,3-h)(1)benzopyran-2-one, Furo[2,3-h]coumarin, 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, delta-lactone, Q-100592, Isopsoralene, Isopsoralen,(S), Furo[5',8]coumarin, AS602868, D01OLO, D0S5KN, AC1L1VO2, AC1Q6BE0, Oprea1_022970, 5-19-04-00447 (Beilstein Handbook Reference), Angelicin, analytical standard, SCHEMBL376379, furano[2,3-h]chromen-8-one, Furo(5',4',7,8)coumarin, Furo[2,3-h]benzopyran-2-one, CTK1H0609, pyrano[6,5-e]benzofuran-2-one, ZINC73700, DTXSID00200321, MolPort-002-508-765, XDROKJSWHURZGO-UHFFFAOYSA-N, 2-furo[2,3-h][1]benzopyranone, HMS1645D18, HY-N0763, 2H-Furo[2,3-H]chromen-2-one #, BDBM50331545, FCH834801, MFCD00064930, NSC404563, AKOS006281380, API0000385, CS-3754, Furo[2,3-h]chromen-2-one(angelicin), MCULE-7782406452, NSC-404563, KS-00000N78, 4CN-1218, AJ-10295, AK111279, AN-45545, AS-35334, CC-29702, LS-70688, SC-47357, ST023306, ZB002644, AB0019705, AX8077901, KB-230742, TR-018581, FT-0603446, N1883, ST24041054, V0167, C09060, W-2783, 523I502, A829042, C-07477, 4-Hydroxy-5-benzofuranacrylic acid .gamma.-lactone, Angelicin plus ultraviolet A radiation [Angelicins], I06-0550, 3-(4-Hydroxy-5-benzofuranyl)-2-propenoic acid .gamma.-lactone, 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, .delta.-lactone, InChI=1/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6, 39310-13-9