ID: 6
InChIKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N SMILES: CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
biological descriptors:
CFTR relevance: CFTR activatorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 47936
synonyms found at PubChem are:
forskolin, Colforsin, 66575-29-9, Coleonol, colforsina, colforsine, colforsinum, Boforsin, Colforsine [French], Colforsinum [Latin], Colforsina [Spanish], Coleonolk, Colforsin [USAN:INN], UNII-1F7A44V6OU, 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one, EINECS 266-410-9, HL 362, NSC 357088, NSC 375489, Forskolin, Coleus forskohlii, CHEMBL52606, 1F7A44V6OU, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate, L 75 1362B, CHEBI:42471, HL-362, NSC375489, 64657-11-0, NCGC00024996-02, L-751362B, 7-beta-Acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one, DSSTox_CID_20484, DSSTox_RID_79500, DSSTox_GSID_40484, Forsklin, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-Dodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-3-vinyl-1H-naphtho(2,1-b)pyran-1-one 5-acetate, 66428-89-5, C22H34O7, ForsLean, 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxy-labd-14-en-11-one, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate, 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))-, 1H-Naphtho(2,1-b)pyran-1-one, dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-pentamethyl-6,10,10b-trihydroxy-, (3R-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))-, 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-, FOK, SMR000471881, CAS-66575-29-9, Ocufors, Timsaponin-C, Colforsin (USAN/INN), D0Y7VM, forskolin/ rolipram mixture, MolMap_000021, AC1L2J1R, AC1Q1L8K, SCHEMBL4928, 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, cid_47936, MLS001066384, MLS001333255, MLS001333256, MLS002172462, MLS002695942, Forskolin, analytical standard, Forskohlii Root Extract (ForsLean)(20% forskohlin), REGID_for_CID_47936, GTPL5190, DTXSID8040484, BCBcMAP01_000132, OHCQJHSOBUTRHG-KGGHGJDLSA-, AOB6380, BIF1031, MolPort-002-493-717, OHCQJHSOBUTRHG-KGGHGJDLSA-N, ZX-AFC000211, Bio1_000443, Bio1_000932, Bio1_001421, HMS2235C17, HMS3267I16, ZINC3977779, Tox21_110940, Tox21_302399, BDBM50010261, MFCD00082317, s2449, AKOS024456384, Tox21_110940_1, ACN-035218, AM81249, CS-1454, DB02587, LMPR0104030004, PXT0000105, SMP1_000128, NCGC00024996-03, NCGC00024996-04, NCGC00024996-05, NCGC00024996-06, NCGC00177971-03, NCGC00255526-01, 5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one, AS-17443, CC-28833, HY-15371, LS-95557, SC-47275, F0855, FT-0626543, V0151, Y0448, 7088-EP2280000A1, 7088-EP2284169A1, 7088-EP2287147A2, 7088-EP2287161A1, 7088-EP2287162A1, 7088-EP2287165A2, 7088-EP2287166A2, 7088-EP2292620A2, 7088-EP2295550A2, 7088-EP2301931A1, 7088-EP2301937A1, 7088-EP2308562A2, 7088-EP2311806A2, 7088-EP2371811A2, C09076, D03584, MLS-0318096.0001, S-7769, C-21901, SR-01000597378, Forskolin, For use in molecular biology applications, Q-200888, SR-01000597378-1, BRD-K09602097-001-04-5, Forskolin, from Coleus forskohlii, >=98% (HPLC), powder, Forskolin, United States Pharmacopeia (USP) Reference Standard, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate, [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate, [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate, [3R-(3?,4a?,5?,6?,6a?,10?,10a?,10b?)]-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one, [3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-5-(Acetyloxy)-3-e thenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one, 1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-, 72569-68-7, InChI=1/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
ID: 2094
InChIKey: SKAIDWFZCIKFIY-XYOKQWHBSA-N SMILES: C=CCOc1ccccc1/C=C(\C#N)/c2c(c(n[nH]2)N)C#N
biological descriptors:
CFTR relevance: CFTR activatorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 5760598
synonyms found at PubChem are:
AC1NXVU7, ZINC8565361, STK389064, AKOS000113050, BAS 00858152, SR-01000418461, SR-01000418461-1, 3-[2-(2-Allyloxy-phenyl)-1-cyano-vinyl]-5-amino-1H-pyrazole-4-carbonitrile, 3-amino-5-[(Z)-1-cyano-2-(2-prop-2-enoxyphenyl)ethenyl]-1H-pyrazole-4-carbonitrile, 5-amino-3-{(Z)-1-cyano-2-[2-(prop-2-en-1-yloxy)phenyl]ethenyl}-1H-pyrazole-4-carbonitrile
ID: 2502
InChIKey: WRINBBKPZKSBMR-UHFFFAOYSA-N SMILES: COc1ccc(cc1)C2c3c([nH]nc3OC(=C2C#N)N)c4ccccc4
biological descriptors:
CFTR relevance: CFTR activatorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 3125753
synonyms found at PubChem are:
6-amino-4-(4-methoxyphenyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, AC1MISAM, Oprea1_228801, Oprea1_341622, Oprea1_817016, MolPort-000-816-520, MolPort-000-919-276, WRINBBKPZKSBMR-UHFFFAOYSA-N, RSC000082, STK744133, AKOS000675459, AKOS003233956, AKOS021990586, CCG-106730, MCULE-1734929398, BAS 01108025, ST071131, J3.663.100G, AK-777/11282102, SR-01000434707, SR-01000434707-1, A1883/0079219, 3-Phenyl-4-(4-methoxyphenyl)-6-amino-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(4-methoxyphenyl)-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(4-methoxyphenyl)-3-phenyl-4H-pyrano[3,2-d]pyrazole-5-carbonitrile, 330158-65-1
ID: 1528
InChIKey: NWCRHCHMUBHHPO-UDWIEESQSA-N SMILES: Cc1ccc(s1)c2cc(n[nH]2)C(=O)N/N=C(\C)/c3ccc(c(c3)OC)OC
biological descriptors:
CFTR relevance: CFTR activatorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 5445606
synonyms found at PubChem are:
AC1NU4WY, MolPort-000-715-177, MolPort-001-805-079, STL024943, ZINC12462536, AKOS005641880, AKOS027282597, N'-(1-(3,4-DI-MEO-PH)ETHYLIDENE)-3-(5-ME-2-THIENYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE, 1299325-63-5, N'-[(1E)-1-(3,4-dimethoxyphenyl)ethylidene]-3-(5-methylthiophen-2-yl)-1H-pyrazole-5-carbohydrazide, N-[(E)-1-(3,4-dimethoxyphenyl)ethylideneamino]-5-(5-methylthiophen-2-yl)-1H-pyrazole-3-carboxamide
ID: 325
InChIKey: CEIXHRDGIFUDQQ-UHFFFAOYSA-N SMILES: c1ccc2c(c1)c(=O)n(c(n2)SCc3ccncc3)Cc4ccco4
biological descriptors:
CFTR relevance: CFTR activatorCategory:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown
CID is 855743
synonyms found at PubChem are:
AC1LH2G9, Oprea1_445291, Oprea1_710553, AKOS002075949, EU-0028216, SR-01000563171, SR-01000563171-1, 3-(furan-2-ylmethyl)-2-(pyridin-4-ylmethylsulfanyl)quinazolin-4-one