Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=4ID: 3085 InChIKey: IGEOJNMYRZUKIK-IBGZPJMESA-NSMILES: C[C@H]1CC(N(C1)C2=C(C=CC(=N2)N3C=CC(=N3)OCCC4(CC4)C(F)(F)F)C(=O)NS(=O)(=O)C5=CC=CC=C5)(C)C
biological descriptors:
CFTR relevance: to be classified
Category: Influence on CFTR function to be classified
Order of interaction to be classified
subcellular compartment to be classified
Category: Influence on CFTR function to be classified
Order of interaction to be classified
subcellular compartment to be classified
CID is 46199801 synonyms found at PubChem are:
Tezacaftor (Racemate), SCHEMBL322363, HMS3652D20, HMS3748O05, AKOS026750399, NCGC00389346-01, 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-Methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxaMide, 1226709-85-8, DA-47741, CS-0009162, FT-0772351, 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-N-[1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)INDOL-5-YL]CYCLOPROPANE-1-CARBOXAMIDE
ID: 7 InChIKey: PURKAOJPTOLRMP-UHFFFAOYSA-NSMILES: CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C
biological descriptors:
CFTR relevance: CFTR stimulator
Category: Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment