previous compound ID: 3011 next compound
InChIKey: RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES: C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 61
"D Herman" "A Schmidt" "JR Riordan" "S Noel" "T Okiyoneda" "JW Kelly" "B Hoch" "GL Lukacs" "JM Gottesfeld" "RA Frizzell" "M Gentzsch" "WE Balch" "EJ Sorscher" "DM Hutt" "JR_3rd Yates" "G Manning" "J Matteson" "JM Pilewski" "WR Skach" "W Kellner" "PJ Thomas" "AP Rodrigues" "Y Matsumura"

chemical graph of compound 3011





CID is 444732
synonyms found at PubChem are:
trichostatin A, 58880-19-6, Trichostatin A (TSA), TSA, Trichostatin, UNII-3X2S926L3Z, CHEBI:46024, (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide, GNF-PF-1011, RTKIYFITIVXBLE-QEQCGCAPSA-N, 3X2S926L3Z, 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-, 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide, Q-201864, Tricostatin A, (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE, 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-, 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-, TSN, trichostatine a, Trichlostatin A, (2E,4E,6R)-7-(4-dimethylaminophenyl)-4,6-dimethyl-7-oxo-hepta-2,4-dienehydroxamic acid, (2E,4E,6R)-7-(4-Dimethylaminophenyl)-N-hydroxy-4,6-dimethyl-7-oxo-hepta-2,4-dienamide, Trichostatin A,TSA, Trichostatin A/TSA, Antibiotic A-300, (R)-Trichostatin A, NCGC_TSA, 1c3r, 3f0r, Trichostatin-A - TSA, AC1L9GSU, A 300, D0NF6F, SCHEMBL19886, MLS006011095, SGCTO-002, SCHEMBL675951, GTPL7005, DTXSID6037063, CHEBI:93196, MolPort-003-959-819, MolPort-044-724-267, ZX-AFC000233, BCPP000035, HMS1362L09, HMS1792L09, HMS1990L09, HMS3403L09, HMS3649O20, BCP01776, EX-A1665, ABP000141, BDBM50005711, LMPK01000055, MFCD03848392, s1045, Trichostatin A from Streptomyces sp., AKOS015899840, ZINC100014731, A-300-I, CCG-208142, CCG-208681, CS-0499, DB04297, RL04219, NCGC00162453-01, NCGC00162453-02, NCGC00162453-03, NCGC00162453-04, NCGC00162453-05, NCGC00162453-15, 3C10, HY-15144, KB-81257, LS-74195, M984, SC-73346, SMR004702883, A8183, M02571, W-5309, 880T196, SR-05000013796, SR-05000013796-3, BRD-K68202742-001-04-1, BRD-K68202742-001-05-8, I14-11732, Trichostatin A, >=98% (HPLC), from Streptomyces sp., UNII-30RHG284Z4 component RTKIYFITIVXBLE-QEQCGCAPSA-N, Trichostatin A??, Vetec(TM) reagent grade, from Streptomyces sp., >=98%, (2E,4E,6R)-7-(4-dimethylaminophenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide, (6R)-N-Hydroxy-4,6-dimethyl-7-oxo-7-[4-(dimethylamino)phenyl]-2,4-heptadienamide, (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide, 7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide, 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)- (9CI), 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, [R-(E,E)]-