previous compound ID: 609 next compound
InChIKey: FMOKUKPRJSMPOI-QRPNPIFTSA-N
SMILES: CC(=O)C[C@@H]1CCCCN1.Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 55


Carlile GW et. al. 2007 (paper)
Correctors of protein trafficking defects identified by a novel high-throughput screening assay.
Chembiochem : a European journal of chemical biology, page 1012-20, volume 8, issue 9, year 2007
"Y Luo" "D Zhang" "GW Carlile" "R Robert" "DY Thomas" "KA Teske" "JW Hanrahan"
DOI: 10.1002/cbic.200700027
PMID: 17497613


Reference Into Function: the appearance of the mutant protein at the cell surface is measured. We used this assay to screen a library of 2000 compounds and have isolated several classes of trafficking correctors that had not previously been identified.


chemical graph of compound 609




CID is 72942005 the link to PubChem record is https://pubchem.ncbi.nlm.nih.gov/compound/72942005

CID is 72942005
synonyms found at PubChem are:
UNII-Q107JES56Y, Q107JES56Y, Pelletierine hydrochloride, (+)-, 2-Propanone, 1-(2S)-2-piperidinyl-, hydrochloride (1:1), 1250851-48-9, UNII-516910XH33 component FMOKUKPRJSMPOI-QRPNPIFTSA-N