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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"GW Carlile" "JW Hanrahan" "R Robert" "KA Teske" "Y Luo" "DY Thomas" "D Zhang"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=30

ID: 13
InChIKey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
SMILES: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

chemical graph of compound 13



CID is 5212
synonyms found at PubChem are:
sildenafil, 139755-83-2, Revatio, VIAGRA, Sildenafil [INN:BAN], UK-92480, UNII-3M7OB98Y7H, Aphrodil (TN), Sildenafil (INN), UK-92,480-10, C22H30N6O4S, HSDB 7305, CHEMBL192, 3M7OB98Y7H, CHEBI:9139, UK 92480-10, 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine, BNRNXUUZRGQAQC-UHFFFAOYSA-N, Caverta, 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one, NCX-911, Revatio (TN), Viagra (TN), 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, Piperazine, 1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-, SMR000752512, 171599-83-0 (citrate), SR-05000001934, NCGC00159496-02, mysildecard, Aphrodil, Vizarsin, Rhucin, Sildenafil#, 1udt, 1xos, 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, 5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo(4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, Rhucin (TN), Spectrum_001555, SpecPlus_000798, AC1L1JUI, Spectrum2_001648, Spectrum3_001892, Spectrum4_000586, Spectrum5_001508, D08KTT, D0Z7ZM, Cambridge id 7030299, SCHEMBL1895, BSPBio_003424, KBioGR_001052, KBioSS_002035, MLS001240224, MLS001304737, MLS006011565, BIDD:GT0352, DivK1c_006894, SPECTRUM1504099, SPBio_001775, GTPL4743, SCHEMBL5795456, SCHEMBL8100377, Jsp002373, DTXSID6023579, BDBM14390, KBio1_001838, KBio2_002035, KBio2_004603, KBio2_007171, KBio3_002927, KS-00000XMX, 2h42, MolPort-002-885-861, HMS1684K08, HMS1922B19, HMS2089M12, HMS2093O17, HMS2233L22, HMS3372N07, HMS3715P17, Sildenafil 1.0 mg/ml in Methanol, ACT02662, BCP05337, AC-938, CCG-21806, CCG-39076, s4684, STL483201, STL483720, ZINC19796168, AKOS008901403, AKOS025397193, CS-1577, DB00203, MCULE-2481702478, NCGC00095099-01, NCGC00095099-02, NCGC00095099-03, NCGC00095099-04, NCGC00370976-03, 5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one, AN-15436, AS-48884, BAS 04213629, BC202768, HY-15025, M901, SC-83326, SMR004703325, SBI-0051920.P002, AB0015440, LS-111655, FT-0601554, C07259, D08514, W-2194, AB00052444-02, AB00052444-03, AB00052444_04, AB00052444_05, 755S832, SR-01000504734, I06-0023, J-007309, SR-01000504734-1, SR-05000001934-1, SR-05000001934-2, BRD-K50128260-001-01-6, BRD-K79759585-001-02-1, BRD-K79759585-048-01-4, 4-((4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydr, Z1522567175, Sildenafil solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one (Sildenafil or Viagra), 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one(Sildenafil), 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1.6-dihydro-7H-pyrazolo[4,3-d]Pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one

ID: 2683
InChIKey: YDVKLIWOUGSPJK-NXENZQSYSA-N
SMILES: C[C@@]12CCC3[C@](C14C(O4)C(=O)O[C@H]2C5=COC=C5)([C@@H](CC6[C@@]3(C(=O)C[C@H](C6(C)C)O)C)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2683



CID is 6708751
synonyms found at PubChem are:
KBio1_001755, Spectrum_000625, SpecPlus_000715, Spectrum2_000443, Spectrum3_000106, Spectrum4_001387, Spectrum5_000094, BSPBio_001692, BSPBio_001778, KBioGR_001714, KBioSS_001105, DivK1c_006811, SPBio_000486, KBio2_001105, KBio2_003673, KBio2_006241, KBio3_000812, CCG-38692, NCGC00179012-01, NCGC00179012-02

ID: 51
InChIKey: NCNXULVCMORARX-NYMFISLZSA-N
SMILES: C[C@@]12CCC3[C@]4(C=C[C@H](C(C4CC(=O)O[C@]3(C1=CC(=O)O[C@H]2C5=COC=C5)C)(C)C)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 51



CID is 6708582
synonyms found at PubChem are:
DEOXYANDIROBIN LACTONE, KBio2_003732, Spectrum_000684, SpecPlus_000167, Spectrum2_000257, Spectrum3_000049, Spectrum4_001331, Spectrum5_000201, BSPBio_001777, KBioGR_001821, KBioSS_001164, DivK1c_006263, SPBio_000074, CHEMBL3039179, SCHEMBL12998316, KBio1_001207, KBio2_001164, KBio2_006300, KBio3_000937, NCGC00179013-01, SR-05000002674, SR-05000002674-1, BRD-A58269583-001-02-0

ID: 2372
InChIKey: VQHSOMBJVWLPSR-RNEZNVSZSA-N
SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC([C@@H](CO)O)[C@@H]([C@H](CO)O)O)O)O)O)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2372



CID is 90657618
synonyms found at PubChem are:
Cellobiitol

ID: 122
InChIKey: AGFVQCSHMSTFBV-UHFFFAOYSA-N
SMILES: C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt]

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 122



CID is 498142
synonyms found at PubChem are:
carboplatin, Cbdca, NSC241240, Carboplatin (USAN), 1,1-Cyclobutanedicarboxylate diammine platinum(II), cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II), cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II), Platinum, diammine[1,1-cyclobutanedicarboxylato(2-)-O,O']-, (SP-4-2)-, 41575-94-4, 7,7-diamino-[?]spiro[3.5]nonane-5,9-dione, Platinum(II), (1, 1-cyclobutanedicarboxylato)diammine-, cis-, Platinum, {diammine[1,1-cyclobutanedicarboxylato(2-)-O,O']-,} (SP-4-2)-, Platinum, diamine(1, 1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)-, AC1LAYHA, azanide; cyclobutane-1,1-dicarboxylic acid; platinum

ID: 1207
InChIKey: KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES: C/C/1=C\CC[C@@]2([C@H](O2)[C@@H]3[C@@H](CC1)C(=C)C(=O)O3)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 1207



CID is 7251185
synonyms found at PubChem are:
parthenolide, 20554-84-1, (-)-Parthenolide, CHEBI:7939, Parthenolide, Tanacetum parthenium, 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone, partenolide, C15H20O3, Prestwick2_000550, Prestwick3_000550, D0M4KE, Epitope ID:115014, SCHEMBL8220, BSPBio_000599, BSPBio_001308, MLS002153872, BPBio1_000659, CHEMBL465158, SCHEMBL13367522, BCBcMAP01_000041, Parthenolide, >=98% (HPLC), MolPort-003-959-089, MolPort-008-268-168, HMS1361B10, HMS1569N21, HMS1791B10, HMS1989B10, HMS2096N21, HMS3402B10, HMS3713N21, 29552-41-8, BCP10404, HY-N0141, ZINC4492886, MFCD00134592, AKOS016010226, CCG-208244, CS-1919, IDI1_033778, NCGC00163415-01, AJ-51217, AS-17479, Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-, SMR001233226, AB0019832, AB00513860, ST24048874, V0355, X-1866, 552P418, Q-100253, Parthenolide, United States Pharmacopeia (USP) Reference Standard, (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, (3aS,10R,11R,11aS,6E)-3-Methylene-6,10-dimethyl-10,11-epoxy-1-oxa-2,3,3a,4,5,8,9,10,11,11a-decahydro-1H-cyclopentacyclodecene-2-one

ID: 65
InChIKey: QGXBDMJGAMFCBF-LUJOEAJASA-N
SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 65



CID is 441302
synonyms found at PubChem are:
EPIANDROSTERONE, 481-29-8, trans-Androsterone, Isoandrosterone, 3Beta-hydroxy-5alpha-androstan-17-one, 3beta-Hydroxyetioallocholan-17-one, epi-andosterone, 5alpha-Androstan-3beta-ol-17-one, iso-Androsterone, d-Epiandrosterone, UNII-8TR252Z538, 3-Epiandrosterone, (3beta,5alpha)-3-hydroxyandrostan-17-one, CHEMBL272195, 3beta-Hydroxy-androstan-17-one, CHEBI:541975, QGXBDMJGAMFCBF-LUJOEAJASA-N, Androsterone, epi-, MFCD00064134, NSC 93996, 8TR252Z538, ST072176, Androstan-17-one, 3-hydroxy-, (3b,5a)-, epi-Androsterone, C19H30O2, (1S,2S,5S,7S,11S,15S,10R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11, 15>]heptadecan-14-one, SMR000718744, Androsterone, (3beta)-, AOX, Prestwick_699, EINECS 207-563-3, 3-beta-Hydroxy-5-alpha-androstan-17-one, AC1L9AXM, Prestwick0_000440, Prestwick1_000440, Prestwick2_000440, Prestwick3_000440, EC 207-563-3, BSPBio_000460, MLS000563092, MLS001304190, MLS001333976, MLS001333977, MLS002153812, SCHEMBL295167, SPBio_002399, BPBio1_000506, MolPort-002-506-907, HMS1569G22, HMS2096G22, HMS2235I04, HMS3713G22, ACT02601, Epiandrosterone (3|A-androsterone), HY-I0352, ZINC3861661, BBL030012, BDBM50236240, LMST02020023, s2832, SBB012505, STK801866, AKOS001582886, CCG-220440, CHM0029415, CS-5183, EBD2157888, NCGC00142619-02, NCGC00142619-04, AC-16141, AS-13045, CC-27483, H110, KB-50541, SC-16224, (3beta, 5alpha)-androstan-3-ol- 17-one, Androstan-17-one,3-hydroxy-, (3b,5a)-, TL8003251, E0374, C07635, J10456, M-1324, 5alpha-Androstan-17-one, 3beta-hydroxy- (8CI), C-18233, SR-01000837513, SR-01000837513-2, W-106055, Androstan-17-one, 3-hydroxy-, (3beta,5alpha)- (9CI), (3S,5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

ID: 801
InChIKey: HBOMLICNUCNMMY-XLPZGREQSA-N
SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 801



CID is 35370
synonyms found at PubChem are:
zidovudine, Azidothymidine, 30516-87-1, Retrovir, 3'-Azido-3'-deoxythymidine, AZT, Zidovudinum, Compound S, Thymidine, 3'-azido-3'-deoxy-, BW A509U, zidovudin, Zidovudinum [Latin], Zidovudina, Aztec, Zidovudina [Spanish], AZT Antiviral, AZT, Antiviral, ZIDOVUDINE [AZT], AZT (Antiviral), BWA509U, Apo-Zidovudine, BW-A 509U, Novo-Azt, Propolis+AZT, azidodeoxythymidine, 3'-Azido-2',3'-Dideoxythymidine, DRG-0004, Retrovir(TM), AZT & Li & EPO, ZDV, UNII-4B9XT59T7S, Retrovir (TN), 3'-Deoxy-3'-azidothymidine, CCRIS 105, Zidovudine EP III, Cpd S, BW-A509U, BWA-509U, Intron A & AZT, Racemic Liposomal AZT, BW-A-509U, HSDB 6515, Liposomal AZT-SN-1, Liposomal AZT-SN-3, Zidovudine+PRO 140, Zidovudine [USAN:INN:BAN:JAN], PC-SOD+AZT, AZT & srCD4, AZT & rIFN.alpha.2, AZT & rsT4, rIFN-beta seron & AZT, 3-Azido-3-deoxythymidine, 3'-Azido-3'-deoxythymidine (AIDS), AZT & EPO, AZT & GM-CSF, AZT & HPA, AZT & sCD4, AZT & SST, CHEMBL129, NSC 602670, AZT & Li & GM-CSF, AZT+PRO 140, Met-SDF-1.beta. & AZT, AZT & Li & IL-1, AZT & Li & IL-6, MLS000028548, 4B9XT59T7S, AZT & IL-1, AZT & IL-2, AZT & IL-6, AZT & Interferon-.alpha.-2, 1-((2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, AZT & Concanavalin A (ConA), AZT & Lymphoblastoid Interferon, AZT & PM-19, CHEBI:10110, Met-SDF-1.beta. & Zidovudine, AZT & rsCD4 & rIFN.alpha.A, HBOMLICNUCNMMY-XLPZGREQSA-N, 3'-azido-3'-deoxythymidine, AZT, DS-4152 & AZT, AZT & Colony-stimulating factor 2, AZT & NP (from PHCA or HSA), K7 [P Ti2 W10 O40], 3&prime;-Azido-3&prime;-deoxythymidine, NCGC00023945-05, AZT & CD4(178)-PE 40, SMR000058351, DSSTox_CID_127, 3'-Azido-3'-deoxythymidine & Erythropoietin, 3'-Azido-3'-deoxythymidine & Sho-Saiko-To, Interferon AD + 3'-azido-3'-deoxythymidine, 3'-Azido-3'-deoxythymidine & Concanavalin A, 3'-Azido-3'-deoxythymidine & Interleukin-1, 3'-Azido-3'-deoxythymidine & Interleukin-2, 3'-Azido-3'-deoxythymidine & Interleukin-6, AZT TRANSPLACENTAL CARCINOGENESIS STUDY, 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione, DSSTox_RID_75386, DSSTox_GSID_20127, Azitidin, 399024-19-2, 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine, 3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin, 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1, 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6, 3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon, SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle), SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle), 3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19, racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle), Antiviral AZT, ZVD, zudovidine, 3' Azido 3' deoxythymidine, Dendrigen, BWA 509U, 4lhm, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione [AZT], 3&prime, Retrovis (TN), 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, 3' Azido 2',3' Dideoxythymidine, 3''-azido-thymidine, AZT & IFN-alpha, Zidovudine [USAN:USP:INN:BAN:JAN], Zidovudine & IFNL1, Zidovudine & IFNL2, Zidovudine & IFNL3, Zidovudine (Retrovir), Spectrum_001348, AZT & IFN.alpha., Zidovudine & IL-29, Zidovudine & IL-28A, Zidovudine & IL-28B, AC1L1TKL, AC1Q2OEK, AZT & Interleukin 29, Opera_ID_1602, Prestwick3_000333, Spectrum2_000927, Spectrum3_001507, Spectrum4_000332, Spectrum5_001101, 3'azido-3'deoxythymidine, AZT & Interleukin 28A, AZT & Interleukin 28B, D01XYJ, D0UF5H, D0YX5A, 3'-azido3'-deoxythymidine, AZT & IFNL1, AZT & IFNL2, AZT & IFNL3, Antiviral, Shanghai Genomics, AZT & Interferon lambda-1, AZT & Interferon lambda-2, AZT & Interferon lambda-3, 3''-Deoxy-3-azidothymidine, BSPBio_000365, BSPBio_003153, KBioGR_000703, KBioSS_001828, Zidovudine (JAN/USP/INN), microthornmicro feminineEthOUO, MLS001055351, MLS001076358, MLS002153202, MLS002222249, Zidovudine & Interleukin 29, DivK1c_000524, SPECTRUM1502109, 3'-deoxy-3'-azido-thymidine, SPBio_000834, Zidovudine & Interleukin 28A, Zidovudine & Interleukin 28B, AZT & IL-28A, AZT & IL-28B, BPBio1_000403, GTPL4825, Zidovudine (JP17/USP/INN), DTXSID8020127, SCHEMBL14615088, AZT & IL-29, CTCE-0422, CTK4I2082, HMS501K06, KBio1_000524, KBio2_001828, KBio2_004396, KBio2_006964, KBio3_002653, KS-00000WOF, Antiviral, Chemokine Therapeutics, 3''-Azido-3''-deoxy-thymidine, MolPort-002-507-286, NINDS_000524, Zidovudine & Interferon lambda-1, Zidovudine & Interferon lambda-2, Zidovudine & Interferon lambda-3, HMS1921J20, HMS2090G11, HMS2092D06, HMS2096C07, HMS2234K17, HMS3259H17, HMS3713C07, Pharmakon1600-01502109, 1-((2R,4R,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, ZINC3779042, 3''azido-2''3''-dideoxythymidine, Tox21_110062, Tox21_110894, Tox21_202203, Tox21_300578, AEe paragraph signa.o paragraph sign, ANW-26899, BBL033764, BDBM50002692, CCG-39924, CZ0012, MFCD00006536, NSC758185, STK801891, AKOS005622576, AKOS015842610, Tox21_110062_1, 3''-azido-2'',3''-dideoxythymidine, DB00495, Flt3 ligand (viral infection) Shanghai, LS-1159, MCULE-8664408343, NC00666, NSC-758185, IDI1_000524, NCGC00014918-01, NCGC00023945-03, NCGC00023945-04, NCGC00023945-06, NCGC00023945-07, NCGC00023945-08, NCGC00023945-09, NCGC00023945-10, NCGC00023945-12, NCGC00023945-13, NCGC00178237-01, NCGC00178237-02, NCGC00254276-01, NCGC00259752-01, AS-13019, CPD000058351, SAM002548971, SBI-0051731.P002, AB0012841, Immunostimulant (viral infection), Shanghai, FT-0601543, Propolis & Thymidine, 3'-azido-3'-deoxy-, S2579, 3'-Azido-3'deoxythymidine & Interferon-alpha, EN300-52518, 3'-Azido-3'-deoxythymidine, >=98% (HPLC), C07210, D00413, J10271, W-5037, 3'-Azido-3'deoxythymidine & Interferon .alpha., 3'-Azido-3'-deoxythymidine, >=99.0% (HPLC), SR-01000000098, SR-05000001587, J-700147, SR-01000000098-3, SR-05000001587-1, BRD-K72903603-001-04-6, BRD-K72903603-001-14-5, Z1723414428, Zidovudine, European Pharmacopoeia (EP) Reference Standard, 3'-Azido-3'-deoxythymidine & Recombinant Interferon-.alpha.-2, Zidovudine, United States Pharmacopeia (USP) Reference Standard, 3'-Azido-3'-deoxythymidine & CD4-Pseudomonas exotoxin A hybrid, Beta interferon(rIFN-beta seron) & 3'-Azido-3'-deoxythymidine(AZT), Lecithinized superoxide dismutase & Thymidine, 3'-azido-3'-deoxy-, 3'-Azido-2',3'-dideoxythymidine & sCD4(soluble recombinant protein), Sulfated polysaccharide-peptidoglycan DS-4152 & 3'-Azido-3'-deoxythymidine, Thymidine, 3'-azido-3'-deoxy- & PRO 140 (Anti-CCR5 monoclonal antibody), Zidovudine, Pharmaceutical Secondary Standard; Certified Reference Material, (AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, (AZT)1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(AZT), 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 3'-Azido-3'-deoxythymidine & Lithium & Granulocyte-macrophage colony-stimulating factor, 3'-Azido-3'deoxythymidine & Recombinant Soluble CD4 & Recombinant Interferon.alpha.A, 4-(4-Azido-5-hydroxy-tetrahydro-furan-2-yl)-5-methyl-3H-pyrazine-2,6-dione, Met-Stromal Cell-derived Factor-1.beta. (Human) & 3'-Azido-3'-deoxythymidine, 1-((2R,4S,5S)-4-(diazoamino)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-((2R,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-((2S,4R,5R)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AzddThd, AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (N3ddThd), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(3''-azido-2'',3''-dideoxythymidine), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(azidothymidine, AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(Zidovudine, AZT), 3'-Azido-3'deoxythymidine & Nanoparticles (from human serum albumin or polyhexylcyanoacrylate), 3-((2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)triaz-1-en-2-ium-1-ide, 3-Azido-1,2,3-trideoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-D-erythro- pentofuranuronic acid

ID: 54
InChIKey: NPOJQCVWMSKXDN-UHFFFAOYSA-N
SMILES: COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 54



CID is 2943
synonyms found at PubChem are:
Chlorthal-dimethyl, dacthal, 1861-32-1, DIMETHYL TETRACHLOROTEREPHTHALATE, Dacthalor, Fatal, Chlorthal-methyl, Tetral, Dimethyl 2,3,5,6-tetrachloroterephthalate, Tetrachloroterephthalic acid dimethyl ester, DAC 4, Chlorthal dimethyl ester, Daktal [Czech], Caswell No. 382, 1,4-Benzenedicarboxylic acid, 2,3,5,6-tetrachloro-, dimethyl ester, UNII-ZU3X5G2QLR, DCPA (VAN), Chlorthal dimethyl, 2,3,5,6-Tetrachloroterephthalic acid dimethyl ester, Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate, NSC 155745, Chlorthal-dimethyl [BSI:ISO], HSDB 358, DAC 893, EINECS 217-464-7, Terephthalic acid, tetrachloro-, dimethyl ester, ZU3X5G2QLR, EPA Pesticide Chemical Code 078701, BRN 1888840, AI3-52124, 2,3,5,6-Tetrachlorphthalsaure-dimethylester, Dimethyl tetrachloro-1,4-benzenedicarboxylate, CHEBI:34664, DAC-893, NPOJQCVWMSKXDN-UHFFFAOYSA-N, Dimethylester kyseliny tetrachlortereftalove [Czech], 2,3,5,6-Tetrachlorphthalsaure-dimethylester [German], FR-0596, NCGC00094521-05, DSSTox_CID_4000, DSSTox_RID_77254, DSSTox_GSID_24000, W-107783, Daktal, CAS-1861-32-1, methyl 2,3,5,6-tetrachloro-4-(methoxycarbonyl)benzoate, Diformic Acid Chlorotitanate, Chlorothal, C10H6Cl4O4, Dactal, CCRIS 9261, Chlorothal-methyl, PubChem20581, Spectrum_001803, ACMC-1CMRC, SpecPlus_000394, Dimethylester kyseliny tetrachlortereftalove, AC1L1ETN, Spectrum2_001876, Spectrum3_000817, Spectrum4_000657, Spectrum5_001944, SCHEMBL53477, BSPBio_002313, KBioGR_001033, KBioSS_002296, SPECTRUM330025, DivK1c_006490, SPBio_001752, AC1Q42F6, Jsp003807, CHEMBL1888079, DTXSID0024000, CTK8B1069, KBio1_001434, KBio2_002294, KBio2_004862, KBio2_007430, KBio3_001813, KS-00002WWL, MolPort-000-627-710, ZINC156678, HY-B2062, Tox21_300379, Tox21_400071, Vegetable turf and ornamental weeder, ANW-23263, CCG-39414, LS-953, NSC155745, SBB007929, AKOS002380307, WLN: 1OVR BG CG EG FG DVO1, ACM1861321, CS-5219, KS-5362, MCULE-3486663201, NSC-155745, RTR-008590, ACM20098413, Dimethyl 2,5,6-tetrachloroterephthalate, NCGC00094521-01, NCGC00094521-02, NCGC00094521-03, NCGC00094521-04, NCGC00094521-06, NCGC00094521-07, NCGC00254510-01, 2,5,6-Tetrachlorphthalsaure-dimethylester, AC-19871, AN-50004, CC-06682, SC-52602, Terechloroterephthalic acid dimethyl ester, ZB006419, DB-044581, Tetrachloroterephthalic acid, dimethyl ester, TR-008590, 1, 2,3,5,6-tetrachloro-, dimethyl ester, DACTHAL (PESTICIDE/FERTILIZERMIXTURE), FT-0625047, ST50409271, Dimethyl ester of tetrachloroterephthalic acid, 61D321, C14744, Chlorthal-dimethyl 10 microg/mL in Cyclohexane, Chlorthal-dimethyl 100 microg/mL in Cyclohexane, A813007, C-20067, DIMETHYL-2,3,5,6-TETRACHLOROTEREPHTHALATE, 2,5,6-Tetrachloroterephthalic acid, dimethyl ester, I01-8411, 2,3,5,6-Tetrachloroterephthalic acid, dimethyl ester, Chlorthal-dimethyl, PESTANAL(R), analytical standard, Dimethyl 2,5,6-tetrachloro-1,4-benzenedicarboxylate, Dimethyl 2,3,5,6-tetrachloro-1,4-benzenedicarboxylate, Terephthalic acid, 2,3,5,6-tetrachloro-,dimethyl ester, Chlorthal-dimethyl (RM, ISO Guide 34) 200 mg/L in n-Hexane, dimethyl 2,3,5,6-tetrakis(chloranyl)benzene-1,4-dicarboxylate, 2,3,5,6-Tetrachloro-1,4-benzenedicarboxilic acid dimethyl ester, 2,3,5,6-Tetrachloro-1,4-benzenedicarboxylic acid dimethyl ester, 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylic acid dimethyl ester, 65862-98-8, 87209-56-1

ID: 424
InChIKey: DCYZWGKBLADIJE-VCDNCRAOSA-N
SMILES: C[C@]12CC[C@](CC1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)(O)Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 424



CID is 91430428


ID: 44
InChIKey: JUVIOZPCNVVQFO-HBGVWJBISA-N
SMILES: CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 44



CID is 6758
synonyms found at PubChem are:
rotenone, 83-79-4, Dactinol, Paraderil, (-)-Rotenone, Tubatoxin, Barbasco, (-)-cis-Rotenone, Derrin, Derris, Cube root, Nicouline, Rotocide, Noxfish, Ronone, Rotenon, Canex, Deril, Liquid Derris, Cube-Pulver, Dri-Kil, Rotessenol, Noxfire, Rotefive, Rotefour, Rotenox, Cubor, Haiari, Mexide, Derris root, Powder and root, Chem-Mite, Pro-nox fish, Cenol garden dust, Curex flea duster, Prenfish, Tubotoxin, Gerane, Prentox, Ro-Ko, Synpren, Derris (insecticide), Chem fish, Pb-nox, Rotenox 5EC, 5'-beta-Rotenone, Green Cross Warble Powder, Chem-Fish Synergized, Prentox Synpren-Fish, Nekoe, Caswell No. 725, Extrax, Cube extract, Foliafume E.C., Fish-Tox, ENT 133, Rotenona [Spanish], Rotenone, commercial, CCRIS 895, Rotenone [BSI:ISO], HSDB 1762, NCI-C55210, 5'beta-Rotenone, EPA Pesticide Chemical Code 071003, UNII-03L9OT429T, AI3-00133, NSC26258, EINECS 201-501-9, NSC 26258, Rotenona, Derris resins, MLS000738056, CHEMBL429023, CHEBI:28201, 03L9OT429T, Rotacide E.C., CUBE, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-alpha-isopropenyl-8,9-dimethoxy-, (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one, (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, (2R-(2alpha,6aalpha,12aalpha))-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)(1)benzopyrano(3,4-b)furo(2,3-h)benzopyran-6(6aH)-one, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12aalpha-Tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, NCGC00017358-05, DSSTox_CID_1248, DSSTox_RID_76038, DSSTox_GSID_21248, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R-(2alpha,6aalpha,12aalpha))-, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-on, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one, Green cross warble, Rotacide, Protax, 5'.beta.-Rotenone, CAS-83-79-4, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, (2R,6aS,12aS)-1,2,6,6a,12,12a- hexahydro-2-isopropenyl-8,9- dimethoxychromeno[3,4-b] furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno(3,4-b)furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one, (2R,6aS,12aS)-2-isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, SR-01000076110, Foliafume, Rotenoid, Roteonone, Nusyn, rote five, WLN: T G5 D6 B666 CV HO MO POT&TT&J IY1&U1 SO1 TO1, Chem-Fish, Foliafume E.C, Rotacide E.C, 5''beta-rotenone, 5'b-Rotenone, Rotocide E.C., (1)Benzopyrano[3,3-h](1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-iospropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6a.alpha.H)-one, 1,2,12,12a.alpha.-tetrahydro-2.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2.alpha.,6a.alpha.,12a.alpha.)]-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2alpha,6aalpha,12aalpha)]-, Derris, JMAF, Prestwick_542, Hydrogenated rotenone, Rotenone (7CI), Rotenone, hydrogenated, Rotenone, >=95%, Spectrum_000065, Spectrum2_000457, Spectrum3_000158, Spectrum4_001638, Spectrum5_000455, D0F7CS, AC1L1N8M, AC1Q4EW8, Lopac0_001112, SCHEMBL42253, BSPBio_001896, isopropenyl(dimethoxy)[?]one, KBioGR_002075, KBioSS_000465, SPECTRUM200013, DivK1c_000947, Rotenone E.C. (7.5%), SPBio_000534, DTXSID6021248, HMS502P09, KBio1_000947, KBio2_000465, KBio2_003033, KBio2_005601, KBio3_001116, inhibits NADH2 oxidation to NAD, NSC8505, JUVIOZPCNVVQFO-HBGVWJBISA-N, MolPort-002-507-351, NINDS_000947, HMS3263O06, 2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-H]chromen-6(6ah)-one, BCP07278, HY-B1756, NSC-8505, TNP00301, ZINC3860715, Tox21_110819, Tox21_201904, Tox21_300695, Tox21_501112, 2901AC, BDBM50135527, CCG-39886, LMPK12060007, MFCD09025614, NSC-26258, SBB006465, AKOS004910398, Tox21_110819_1, API0004105, CS-6067, DB11457, LP01112, LS-1830, MCULE-7287067191, MCULE-7415617623, RL05168, SDCCGMLS-0066415.P001, IDI1_000947, NCGC00017358-01, NCGC00017358-02, NCGC00017358-03, NCGC00017358-04, NCGC00017358-06, NCGC00017358-07, NCGC00017358-08, NCGC00017358-09, NCGC00017358-10, NCGC00017358-11, NCGC00017358-14, NCGC00017358-15, NCGC00094382-01, NCGC00094382-02, NCGC00094382-03, NCGC00094382-04, NCGC00094382-05, NCGC00254603-01, NCGC00259453-01, NCGC00261797-01, AJ-46043, AK115691, AN-24066, AS-10183, NCI60_002093, SC-66514, SMR000393729, ST057261, AX8150549, ST2413787, EU-0101112, R0090, Rotenone, PESTANAL(R), analytical standard, TRANSGENIC MODEL EVALUATION (ROTENONE), C07593, R 8875, 26914-EP2275422A1, 26914-EP2280009A1, 26914-EP2305662A1, 26914-EP2308857A1, 26914-EP2314583A1, 599T610, SR-01000076110-2, SR-01000076110-5, SR-01000076110-6, W-104134, BRD-K08316444-001-01-9, BRD-K08316444-001-05-0, ROTENONE (SEE ALSO TRANSGENICMODEL EVALUATION (ROTENONE)), (1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0^{3,11}.0^{4,8}.0^{14,19}]henicosa-3(11),4(8),9,14(19),15,17-hexaen-12-one, (2R,6a5,12axS)-1,2,12,12a-tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-H)(1)benzopyran-6(6aH)-one, (2r,6as,12as)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxybenzopyrano(3,4-b)furo(2,3-h)benzopyran-6-one, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-one, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy- (8CI), [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)- (9CI), [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-o ne, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h) (1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 9CI, 12679-58-2, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-on e, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Tubatoxin 1,2,12,12a,-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]-benzopyran-6(6aH)-one

ID: 1557
InChIKey: ODFJOVXVLFUVNQ-UHFFFAOYSA-N
SMILES: CC(=O)NC1=C(C=CC(=C1)[As](=O)(O)O)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 1557



CID is 1985
synonyms found at PubChem are:
acetarsol, Acetarsone, Acetphenarsine, Amoebal, Arsaphen, Dynarsan, Stovarsol, Mexyl, 97-44-9, Arsonine, Disparicida, Ginarsol, Gynoplix, Kharophen, Kubarsol, Limarsol, Malagride, Monargan, Osarsole, Osvarsan, Osvarson, Pallicid, Spirocid, Spirozid, Stovarsal, Stovarsolan, Vagisept, Vagoflor, Amarsan, Devegan, Nilacid, Oralcid, Orarsan, Osarsal, Osarsol, Paroxyl, Goyl, Fourneau 190, Acetarsolum, Acetarsolo, Chrlich 594, Ehrlich 594, Osarsolum, Sanogyl, N-Acetyl-4-hydroxy-m-arsanilic acid, Acetarsolo [DCIT], Acetarsol [INN:BAN], 3-Acetamido-4-hydroxybenzenearsonic acid, 3-Acetylamino-4-hydroxyphenylarsonic acid, Acetarsolum [INN-Latin], C8H10AsNO5, 3-Acetamido-4-hydroxy-phenylarsonic acid, UNII-806529YU1N, Acetamino-hydroxyphenyl-arsonsaeure, 190 F, F 190, m-ARSANILIC ACID, N-ACETYL-4-HYDROXY-, EINECS 202-582-3, NSC 13160, 3-Acetamido-4-hydroxyphenylarsonsaeure, BRN 2941984, AI3-16141, MLS000028389, MLS000736495, NSC13160, 806529YU1N, SVC, 3-Acetamido-4-hydroxyphenylarsonic acid, NCGC00094812-01, SMR000058626, (3-acetamido-4-hydroxyphenyl)arsonic acid, DSSTox_CID_25847, DSSTox_RID_81169, DSSTox_GSID_45847, Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)-, Arsonic acid, [3-(acetylamino)-4-hydroxyphenyl]-, S.V.C., WLN: Q-AS-QO&R DQ CMV1, WLN: Q-AS-QO & R DQ CMV1, CAS-97-44-9, [3-(Acetylamino)-4-hydroxyphenyl]arsonic acid, Acetarsone [INN:NF], Acetarsol (INN), Acetarsol (Acetarsone), Spectrum_000588, Acetarsone, >=99%, Opera_ID_176, Spectrum2_000104, Spectrum3_000595, Spectrum4_000384, Spectrum5_000640, AC1L1CO2, BSPBio_002070, KBioGR_000907, KBioSS_001068, 3-16-00-01132 (Beilstein Handbook Reference), MLS001148100, DivK1c_000002, SCHEMBL156373, SPECTRUM1500616, SPBio_000088, AC1Q5A60, CHEMBL1330792, DTXSID9045847, HMS500A04, KBio1_000002, KBio2_001068, KBio2_003636, KBio2_006204, KBio3_001570, NSC3247, CHEBI:135135, MolPort-003-665-580, NINDS_000002, HMS1921K13, HMS2092E06, HMS2235C23, HMS3371H07, Pharmakon1600-01500616, 64046-96-4 (calcium salt), NSC-3247, Tox21_111336, 7891AF, CCG-39708, NSC-13160, NSC757386, AKOS015894435, Tox21_111336_1, KS-1320, NSC-757386, IDI1_000002, 2-ACETAMINOPHENOL-4-ARSONIC ACID, 5892-48-8 (mono-hydrochloride salt), NCGC00094812-02, NCGC00094812-03, NCGC00094812-05, LS-21674, NCI60_002818, 64046-96-4 (unspecified calcium salt), SBI-0051558.P002, (3-acetamido-4-hydroxy-phenyl)arsonic acid, FT-0621732, 55588-51-7 (unspecified hydrochloride salt), D07110, 33425-EP2274983A1, 33425-EP2305655A2, 33425-EP2311815A1, 33425-EP2371823A1, AB00052127_12, AB00052127_13, SR-01000695452, I04-9258, SR-01000695452-3, W-204159, Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)- (9CI)

ID: 609
InChIKey: FMOKUKPRJSMPOI-QRPNPIFTSA-N
SMILES: CC(=O)C[C@@H]1CCCCN1.Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 609



CID is 72942005
synonyms found at PubChem are:
UNII-Q107JES56Y, Q107JES56Y, Pelletierine hydrochloride, (+)-, 2-Propanone, 1-(2S)-2-piperidinyl-, hydrochloride (1:1), 1250851-48-9, UNII-516910XH33 component FMOKUKPRJSMPOI-QRPNPIFTSA-N

ID: 974
InChIKey: IOTBHDLEPFTSHN-YUJBZOGSSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C3[C@@]1([C@]45[C@H](O4)C(=O)OC(C5(CC3)C)C6=COC=C6)C)(C(C[C@H](C2(C)C)O)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 974



CID is 88984420
synonyms found at PubChem are:
SCHEMBL12948351

ID: 24
InChIKey: ZQSIJRDFPHDXIC-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 24



CID is 5281708
synonyms found at PubChem are:
daidzein, 486-66-8, 4',7-Dihydroxyisoflavone, Daidzeol, 7,4'-Dihydroxyisoflavone, 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Diadzein, 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-, 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one, 7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, UNII-6287WC5J2L, CCRIS 7600, K 251b, 4,7-Dihydroxyisoflavone, EINECS 207-635-4, BRN 0231523, CHEMBL8145, 4',7-Dihydroxy-iso-flavone, d-(+)-alpha-methylbenzylamine, 4&prime;,7-Dihydroxyisoflavone, CHEBI:28197, ZQSIJRDFPHDXIC-UHFFFAOYSA-N, 6287WC5J2L, Daidzein,(S), 7-Hydroxy-3-(4-hydroxy-phenyl)-chromone, DSSTox_CID_2310, DSSTox_RID_76543, DSSTox_GSID_22310, Q-200924, CAS-486-66-8, SMR000326832, Daidzein (6CI), SR-01000075492, NPI 031E, PubChem9841, AC1NQYXY, Spectrum_000255, Tocris-1417, BiomolKI_000060, Spectrum2_000053, Spectrum3_000191, Spectrum4_001964, Spectrum5_000857, Lopac-D-7802, 4 ,7-Dihydroxyisoflavone, BiomolKI2_000066, D0N9CG, D0SY2M, UPCMLD-DP052, 4',7-dihydroxy isoflavone, 4',7-dihydroxy-Isoflavone, Lopac0_000412, Oprea1_182317, Oprea1_305345, SCHEMBL19814, BSPBio_001741, Daidzein, analytical standard, KBioGR_002432, KBioSS_000735, SPECTRUM200789, 5-18-04-00089 (Beilstein Handbook Reference), MLS000859973, MLS001304056, MLS006011853, BIDD:ER0120, DivK1c_001023, SPBio_000205, Daidzein, >=98%, synthetic, Isoflavone, 4',7-dihydroxy-, BIMB2005, BMK1-F12, GTPL2828, MEGxm0_000123, NPI-031E, d-(+)-alpha-methylbenzyl amine, DTXSID9022310, UPCMLD-DP052:001, ACon0_001477, ACon1_000543, BDBM23420, HMS503M07, K-251b, KBio1_001023, KBio2_000735, KBio2_003303, KBio2_005871, KBio3_001241, KS-00000MGD, AOB5524, OR1035T, 4',7-Dihydroxyisoflavone, 97%, MolPort-000-003-017, NINDS_001023, ZX-AFC000144, 7,4'-Dihydroxy-isoflavone (3a), HMS1922P18, HMS2233H24, HMS3261C06, HMS3267J04, HMS3370C03, HMS3468L18, HMS3649B20, HMS3655A18, ALBB-015933, BCP28286, HY-N0019, ZX-AN014640, ZX-AT022124, Tox21_201444, Tox21_303650, Tox21_500412, BBL010490, BS0244, CCG-38357, CD-190, LMPK12050038, MFCD00016954, s1849, SBB066056, STK801626, ZINC18847034, Daidzein (4',7-Dihydroxyisoflavone), 7-hydroxy-3-(4-hydroxyphenyl)-4H-, AKOS002385052, Isoflavone, 4',7-dihydroxy- (8CI), AC-6035, ACN-034764, CS-2332, Daidzein, purum, >=98.0% (TLC), KS-5260, LP00412, LS-2143, MCULE-8239511422, SDCCGMLS-0066422.P001, IDI1_001023, SMP1_000089, NCGC00015365-01, NCGC00015365-02, NCGC00015365-03, NCGC00015365-04, NCGC00015365-05, NCGC00015365-06, NCGC00015365-07, NCGC00015365-08, NCGC00015365-09, NCGC00015365-10, NCGC00015365-11, NCGC00015365-12, NCGC00015365-13, NCGC00015365-14, NCGC00015365-15, NCGC00015365-16, NCGC00015365-17, NCGC00015365-18, NCGC00025156-01, NCGC00025156-02, NCGC00025156-03, NCGC00025156-04, NCGC00025156-05, NCGC00025156-06, NCGC00025156-07, NCGC00025156-08, NCGC00025156-09, NCGC00025156-10, NCGC00168978-01, NCGC00168978-02, NCGC00257367-01, NCGC00258995-01, NCGC00261097-01, AJ-70673, AK-94232, AN-45238, CC-17424, KB-49550, SC-46504, ST057515, AB0010476, AB1004493, BB 0259520, D2668, EU-0100412, FT-0080019, FT-0603419, FT-0665448, N1862, R1341, 7-hydroxy-3-(4-hydroxyphenyl)-chromen-4-one, 7-Hydroxy-3-(4-hydroxy-phenyl)-chromen-4-one, 7-HYDROXY-3-(4-HYDROXYPHENYL)CHROMONE, C10208, D 7802, D17500, S00273, US8552057, 7, AB00052712-08, AB00052712_10, 486D668, C-15745, Daidzein, primary pharmaceutical reference standard, I06-0011, SR-01000075492-1, SR-01000075492-3, SR-01000075492-7, SR-01000075492-8, BRD-K42095107-001-02-3, BRD-K42095107-001-05-6, BRD-K42095107-001-08-0, SR-01000075492-12, 80E3ED75-D852-4D97-9BD6-B5ADE7EA25A1, 7-Hydroxy-3-(4-hydroxy-phenyl)-4H-1-benzo-pyran-4-one, UNII-71B37NR06D component ZQSIJRDFPHDXIC-UHFFFAOYSA-N, Daidzein, United States Pharmacopeia (USP) Reference Standard, Daidzein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,7-Dihydroxyisoflavone; 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7-Hydroxy-3-(4-hydroxyphenyl)chromone

ID: 70
InChIKey: SFLOGVVDXPCWGR-UHFFFAOYSA-N
SMILES: C12=C(NC(=O)C(=O)N1)NC(=NC2=O)N

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 70



CID is 10291
synonyms found at PubChem are:
LEUCOPTERIN, Leikopterin, Leukopterin, 492-11-5, 2-Amino-4,6,7-trihydroxypteridine, UNII-54RIE2BQ10, 54RIE2BQ10, 2-amino-5,8-dihydro-1H-pteridine-4,6,7-trione, 4,6,7(3H)-Pteridinetrione, 2-amino-5,8-dihydro-, 2-aminopteridine-4,6,7(3H,5H,8H)-trione, 2-Amino-4,6,7-trihydroxypyrimido(4,5-b)pyrazine, 2-Amino-4,6,7-trihydroxypyrimido[4,5-b]pyrazine, 2-Aminopteridine-4,6,7-triol, EINECS 207-747-3, NSC 93740, 6,7-dihydroxypterin, Spectrum_001136, SpecPlus_000324, Spectrum2_000587, Spectrum3_000761, Spectrum4_001724, Spectrum5_000488, AC1L1UW2, NCIOpen2_001382, BSPBio_002402, KBioGR_002108, KBioSS_001616, DivK1c_006420, SCHEMBL968371, SPECTRUM1500874, SPBio_000434, CHEMBL3039245, SCHEMBL12948394, KBio1_001364, KBio2_001616, KBio2_004184, KBio2_006752, KBio3_001622, 2-Amino-4,7-trihydroxypteridine, DTXSID00197707, MolPort-000-828-206, MolPort-002-511-804, SFLOGVVDXPCWGR-UHFFFAOYSA-N, NSC93740, CCG-38510, NSC-93740, ZINC18247079, AKOS006227881, AKOS022505738, FCH1191668, MCULE-6696393574, SDCCGMLS-0066681.P001, NCGC00095646-01, NCGC00095646-02, FT-0691535, 2-Amino-4,7-trihydroxypyrimido[4,5-b]pyrazine, 4,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro-, 4,7(3H)-Pteridinetrione, 2-amino-5,8-dihydro-, C-55951, 2-Amino-5,8-dihydro-4,6,7(1H)-pteridinetrione #, 4,6,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro-, 4,6,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro- (8CI)(9CI)

ID: 27
InChIKey: AUYYCJSJGJYCDS-LBPRGKRZSA-N
SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 27



CID is 5920
synonyms found at PubChem are:
liothyronine, triiodothyronine, 3,3',5-Triiodo-L-thyronine, 6893-02-3, Liothyronin, Tresitope, 3,5,3'-triiodothyronine, L-Liothyronine, triothyrone, Liothyroninum, Liotironina, 3,5,3'-Triiodo-L-thyronine, L-T3, T3, Triiodo-L-thyronine, Lyothyronine, 3,3',5-Triiodothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, L-3,5,3'-Triiodothyronine, 3,5,3'TRIIODOTHYRONINE, (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid, T3 (amino acid), T3 (Hormone), L-3,3',5-TriioDOThyronine, T3 liothyronine, Liothyronine [INN:BAN], Euthroid-1, Euthroid-2, Euthroid-3, Thyrolar-1, Thyrolar-2, Thyrolar-3, Liotironina [INN-Spanish], Tri-Thyrotope, Euthroid-0.5, Thyrolar-0.5, Liothyronine (INN), T3 (VAN), Triiodothyronine, l-, Thyrolar-0.25, THYROID HORMONE, 3,5,3'-Tri-iodo-L-thyronine, CHEBI:18258, T3 (Triiodothyronine), Triiodothyronine (T3), L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, Triomet-131, T3 (LIOTRIX), Liothyroninum [INN-Latin], CHEMBL1544, UNII-06LU7C9H1V, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine, (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid, 06LU7C9H1V, 3,3',5-Triiodothyronine, L-, HSDB 3110, Triiodo-thyroninum, AUYYCJSJGJYCDS-LBPRGKRZSA-N, EINECS 229-999-3, MFCD00002593, NSC 80203, 4-(3-Iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine, BRN 2710227, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, L-triiodothyronine, L-3-(4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine, Alanine, 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-, L-, Cytomel (TN), DSSTox_CID_3216, DSSTox_RID_76928, DSSTox_GSID_23216, TRIIODOTHYRONINE (T3 OR LIOTHYRONINE, ACTIVE) (6-11%), CAS-6893-02-3, SR-05000000455, Cyronine, NSC-46046, C15H12I3NO4, 1xzx, Tertroxin (TN), 5714-08-9, Prestwick_135, PubChem20012, Spectrum_001445, Prestwick0_000853, Prestwick1_000853, Prestwick2_000853, Prestwick3_000853, Spectrum2_001984, Spectrum3_001887, Spectrum4_000326, Spectrum5_001793, T-3, Liothyroninum[INN-Latin], L-T3|||L-Liothyronine, D0D8QI, D0S6JG, Epitope ID:131324, AC1L1LF0, SCHEMBL8300, NCIStruc1_000449, Liothyronine modified release, REGID_for_CID_5920, BSPBio_000865, BSPBio_003394, KBioGR_000671, KBioGR_002568, KBioSS_001925, KBioSS_002577, 3,3'5-Triiodo-L-thyronine, MLS000028458, 3,5,3'-triodo-L-thyronine, SPBio_002167, SPBio_002786, BPBio1_000953, GTPL2634, L-3,3',5-triiodo-Thyronine, 3,3',5-Trichloro-L-thyromine, 3,3\',5-triiodo-L-thyronine, DTXSID8023216, BCBcMAP01_000192, BDBM18860, CTK1A2555, HY-A0070A, KBio2_001925, KBio2_002568, KBio2_004493, KBio2_005136, KBio2_007061, KBio2_007704, KBio3_002897, KBio3_003046, (2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid, cMAP_000088, MolPort-003-850-717, HMS1570L07, HMS2097L07, HMS2235A22, HMS3714L07, ZINC3830999, Tox21_110029, Tox21_301943, ANW-60592, CT-833, NCGC00013556, 3,5,3'-triiodo-L-thyronine (T3), Thyronine, 3,3',5-triiodo-, L-, AKOS016003266, 3,3',5-Triiodo-L-thyronine, 95%, AM83597, CCG-220853, CS-4141, DB00279, SMP1_000179, NCGC00013556-01, NCGC00013556-02, NCGC00013556-03, NCGC00013556-04, NCGC00096669-01, NCGC00096669-02, NCGC00255336-01, [125I]T3, AS-17446, KB-28438, KB-99685, LS-16137, SC-11044, SMR000058402, SBI-0206718.P001, DB-021796, Thyronine, 3,3',5-triiodo-, L-(6CI), TR-031350, Thyronine, 3,3',5-triiodo-, L- (6CI), C02465, D08128, 893T023, SR-01000003143, SR-01000003143-4, SR-05000000455-2, SR-05000000455-3, 3,5,3 inverted exclamation marka-Triiodo-L-thyronine, BRD-K89152108-001-03-3, 3,3',5-Triiodo-L-thyronine, >=95% (HPLC), powder, Z2216208625, L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-(9CI), UNII-O48UO55HR0 component AUYYCJSJGJYCDS-LBPRGKRZSA-N, L-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-Alanine, L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- (9CI), Liothyronine, United States Pharmacopeia (USP) Reference Standard, 3,3',5 Triiodothyronine (T3), IRMM(R) certified Reference Material, (2S)-2-AMINO-3-[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]PROPANOIC ACID, (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid, Liothyronine, Pharmaceutical Secondary Standard; Certified Reference Material, 3,3',5-Triiodo-L-thyronine (T3) solution, 100 mug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, 57164-27-9, 7013-53-8, (2S)-2-azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate, AC1OFCLR, CHEBI:533015, 3,3',5-triiodo-L-thyronine zwitterion, 4-(3-iodo-4-hydroxy-phenoxy)-3,5-diiodophenylalanine, (S)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]-propionic acid

ID: 33
InChIKey: DUEPRVBVGDRKAG-UHFFFAOYSA-N
SMILES: CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 33



CID is 2566
synonyms found at PubChem are:
carbofuran, Furadan, 1563-66-2, Curaterr, Yaltox, Chinufur, Crisfuran, Furacarb, Furadan 3G, Furadan G, Furadan 4f, Carbofurane, Pillarfuran, Kenofuran, Niagara 10242, Karbofuranu, Brifur, BAY 70143, Niagara nia-10242, Bayer 70143, FMC 10242, NIA 10242, Carbodan, Furodan, Karbofuranu [Polish], Me f248, Caswell No. 160A, Carbofuran [ANSI:BSI:ISO], 2,2-Dimethyl-7-coumaranyl N-methylcarbamate, ENT 27,164, 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate, OMS 864, 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate, BAY 78537, CCRIS 4017, Furadane, D 1221, CHEBI:34611, 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate, HSDB 1530, OMS-864, C2292-59A, EINECS 216-353-0, UNII-SKF77S6Y67, NIA-10242, 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate, 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate, EPA Pesticide Chemical Code 090601, NSC 167822, BRN 1428746, Furadan 75 WP, AI3-27164, Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, Spectrum_001895, SpecPlus_000516, 2,2-Dimethyl-2,2-dihydrobenzofuranyl-7 N-methylcarbamate, Spectrum2_001871, Spectrum3_000848, Spectrum4_000688, Spectrum5_002012, 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate, Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester, Oprea1_828936, BSPBio_002435, KBioGR_001155, KBioSS_002425, SPECTRUM330057, DivK1c_006612, 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, SPBio_001742, SKF77S6Y67, C12H15NO3, KBio1_001556, KBio2_002419, KBio2_004987, KBio2_007555, KBio3_001935, DUEPRVBVGDRKAG-UHFFFAOYSA-N, 5-17-04-00048 (Beilstein Handbook Reference), N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7 [Polish], LS-900, NSC167822, (2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate, NCGC00094541-01, NCGC00094541-02, WLN: T56 BOT&J C1 C1 IOVM1, 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate, 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate), DSSTox_CID_249, C14291, CARBOFURAN (PESTICIDE/FERTILIZER MIXTURE), DSSTox_RID_75463, DSSTox_GSID_20249, Q-200797, 2,2-Dimethyl-2,3-dihydrobenzoduranyl-7-N-methylcarbamate, 7-Benzofurano, 2,3-dihydro-2,2-dimethyl, methylcarbamate, Diafuran, Sunfuran, Terafuran, Brifer, Furadan F, CAS-1563-66-2, Curater, Tripart nex, Carbofuran mixture, Carbofuran, 98%, Niagaral 242, Sipcam UK carbosip 5G, AC1L1DYQ, SCHEMBL21656, BIDD:ER0379, Carbofuran, analytical standard, 426008_ALDRICH, 45370_RIEDEL, CHEMBL416081, DTXSID9020249, CTK8F8460, ZINC56963, N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7, Tox21_201955, Tox21_300623, BDBM50064619, CCG-39409, ZINC00056963, AKOS015907855, Carbofuran 100 microg/mL in Methanol, NA 2757, NSC-167822, Carbofuran 10 microg/mL in Cyclohexane, NCGC00094541-03, NCGC00094541-04, NCGC00094541-05, NCGC00254481-01, NCGC00259504-01, AC-10588, AN-49451, CC-25405, O719, ZB001897, SBI-0052542.P002, 2,2-dimethyl-7-benzofuranyl methylcarbamate, 2,2-dihydrobenzofuranyl-7 N-methylcarbamate, 2,2-dimethylbenzofuranyl-7-N-methylcarbamate, FT-0602922, Carbofuran, PESTANAL(R), analytical standard, 563C662, A809741, C-12281, I14-2658, (2,2-dimethyl-3H-benzofuran-7-yl) N-methylcarbamate, 2,2-DIMETHYL-7-BENZOFURANOL, METHYLCARBAMATE, BRD-K53570330-001-01-2, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl methylcarbamate, 7-Benzofuranol,3-dihydro-2,2-dimethyl-, methylcarbamate, 2, 3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, 2, 3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-benzofurane-7-yl methyl-carbamate, 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-methyl-carbamate, 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate #, 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-methylcarbamate, 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, 9CI, Carbamic acid, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester, Carbamic acid, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, N-methylcarbamic acid (2,2-dimethyl-3H-benzofuran-7-yl) ester, 2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANOL, METHYLCARBAMATE, Benzofuran-7-ol, 2,3-dihydro, 2,2-dimethyl, N-methylcarbamate, Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester, Carbofuran;2,2-Dimethyl-2,2-dihydrobenzofuranyl-7-N-methylcarbamate; 2,2-Dimethyl-2,3-dihydrobenzofuranyl 7-methylcarbamate; 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate;, InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14

ID: 57
InChIKey: ODLCLZLDYDHRGT-NEGPAABLSA-N
SMILES: CC(=O)O[C@@H]1C[C@@H]2[C@@]([C@@H]3[C@@]1([C@]45[C@H](O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)([C@H](C[C@H](C2(C)C)OC(=O)C)OC(=O)C)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 57



CID is 21596331
synonyms found at PubChem are:
Khivorin, 2524-38-1, D-Homo-24-nor-17-oxachola-20,22-dien-16-one, 1,3,7-tris(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (1a,3alpha,5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-, SCHEMBL598261, CHEMBL1075850, DTXSID70179898, 1,3,7-Tris(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-D-homo-24-nor-17-oxachola-20,22-dien-16-one (1a,3alpha,5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-

ID: 1296
InChIKey: LPLVUJXQOOQHMX-QWBHMCJMSA-N
SMILES: C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 1296



CID is 14982
synonyms found at PubChem are:
Glycyrrhizic acid, glycyrrhizin, Glycyrrhizinic acid, 1405-86-3, Glycyron, Glycyrrhetinic acid glycoside, glyzyrrhizin, 18beta-Glycyrrhizic acid, 18-beta-Glycyrrhizic acid, Glycyrrizin, Liquorice, UNII-6FO62043WK, Rizinsan K2 A2 (free acid), HSDB 496, EINECS 215-785-7, C42H62O16, Glycyrrhizin [JAN], NSC 167409, NSC 234419, BRN 0077922, CHEMBL441687, NSC 2800, beta-Glycyrrhizin, CHEBI:15939, Dipotassium glycyrrhizinate, 6FO62043WK, DSSTox_CID_27006, DSSTox_RID_82047, DSSTox_GSID_47006, Glycyram, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, 20beta-Carboxy-11-oxo-30-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, 30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosiduronic acid, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuron osyl-, Glizigen, Neo-Umor, Zinc Glycyrrhizate, (3beta,20beta)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1- 7-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1- 7-glucopyranuronosyl-, CAS-1405-86-3, Glycyrrhizin (Glycyrrhizic Acid), potenlini, Glycyrrhizicacid, CCRIS 8444, NSC-167409, NSC-234419, NCGC00183128-01, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxy-tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid, Glycyrrhizic acid, 2K, beta-Glycyrrhizinic acid, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxy-tetrahydropyran-3-yl]oxy-3,4,5-trihydr, D0T8QB, AC1L24WN, AC1Q5R7O, Glycyrrhizia uralensis Fisch, SCHEMBL17684, 4-18-00-05156 (Beilstein Handbook Reference), BIDD:ER0363, GTPL4688, DTXSID8047006, LPLVUJXQOOQHMX-QWBHMCJMSA-N, MolPort-006-113-280, HY-N0184, Tox21_111520, Tox21_113426, Tox21_303493, BDBM50185127, s2302, ZINC96015174, AKOS015893086, AKOS015969345, CS-7695, GM-1292, NCGC00257455-01, NCGC00386162-02, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-, AN-40676, AS-13001, CC-29044, E958, LS-72973, KB-276753, ST2419401, FT-0080165, G0150, N1792, J10040, AB01566834_01, 405G863, C-23548, I04-1276, Q-201172, BRD-K83486494-318-01-5, (2S,3S,4S,5R,6R)-6-(((2S,3R,4S,5S,6S)-6-carboxy-2-(((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,1, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid, (2S,3S,4S,5R,6S)-6-{[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-5-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid, (3.beta.,20.beta.)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-.beta.-1- 7-glucopyranuronosyl-.alpha.-D-glucopyranosiduronic acid, 1208112-19-9, 139014-59-8, 18933-02-3, 2a,14,14a,14b-icosahydropicen-3-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, 31261-47-9, 47897-45-0, 47897-48-3, 70055-50-4, 79165-07-4, 947339-02-8

ID: 58
InChIKey: OENHQHLEOONYIE-JLTXGRSLSA-N
SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 58



CID is 5280489
synonyms found at PubChem are:
beta-carotene, 7235-40-7, beta Carotene, beta,beta-Carotene, Betacarotene, Provitamin A, Solatene, Carotaben, Provatene, all-trans-beta-Carotene, Serlabo, Natural Yellow 26, Karotin, KPMK, C.I. Food Orange 5, Solatene (caps), Karotin [Czech], Food orange 5, Zlut prirodni 26, Betacarotenum [Latin], Betacaroteno [Spanish], Lucaratin, BetaVit, beta-Carotin, beta-Karotin, beta;-Carotene, .beta. Carotene, .beta.-Carotene, beta-Carotene, all-trans-, Betacarotenum [INN-Latin], C.I. 75130, Betacaroteno [INN-Spanish], Zlut prirodni 26 [Czech], UNII-01YAE03M7J, NSC 62794, CCRIS 3245, HSDB 3264, Diet,beta-carotene supplementation, E160A, EINECS 230-636-6, all-trans-.beta.-Carotene, CI 40800, CI 75130, MLS001066383, .beta.,.beta.-Carotene, 01YAE03M7J, CHEBI:17579, OENHQHLEOONYIE-JLTXGRSLSA-N, NSC62794, Betacarotene (INN), Betacarotene [INN], (all-E)-1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene), 1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene), (all E)-, 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene, NCGC00096081-01, SMR000112037, 116-32-5, 2,2'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(1,3,3-trimethylcyclohex-1-ene), Cyclohexene, 1,1'-(3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethyl-, (all-E)-, .beta.-Carotene, all-trans-, b-Carotene, Provitamin A1, Betacaroteno, Betacarotenum, Vetoron, trans-B-Carotene, 1,1'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl]bis(2,6,6-trimethylcyclohexene), trans-beta-Carotene, beta carotene [USAN], SR-01000763803, Beta carotene [USAN:USP], Solate, beta-Carotine, beta -carotene, Carotene, .beta., Solatene (TN), Cyclohexene, 1,1'-(3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6,6-trimethyl-, (all-E)-, I(2)-Carotene, Beta Carotene Natural, beta Carotene (USP), trans-.beta.-Carotene, Carotene, Provitamin A, all trans beta-Carotene, all-E-.beta.-Carotene, AC1NQX3D, DSSTox_CID_253, Spectrum5_000505, .beta., .beta.-Carotene, bmse000832, D0MY8N, EC 230-636-6, AC1Q28DI, (9Z,13Z)-beta-Carotene, CHEMBL1293, DSSTox_RID_75466, BIDD:PXR0110, DSSTox_GSID_20253, BSPBio_003404, DTXSID3020253, BDBM54988, cid_5280489, HMS501A12, .beta.,.beta.-Carotene, neo B, MolPort-001-785-959, HMS2091M17, Pharmakon1600-01500143, ZINC6845076, beta-Carotene, >=97.0% (UV), Tox21_111557, C39H54, CC0205, CCG-36062, LMPR01070001, NSC755910, s1767, AKOS015896682, AC-1869, DB06755, LS-1621, NSC-755910, SDCCGMLS-0066579.P001, IDI1_000330, NCGC00096081-02, 31797-85-0, AN-14537, AS-13354, BC208855, H982, SC-19470, ST097774, CAS-7235-40-7, SBI-0051295.P003, AB2000280, N1547, 3046-EP2298772A1, 3046-EP2308839A1, C02094, D03101, J10299, AB00051925_06, AB00051925_07, beta-Carotene, Vetec(TM) reagent grade, >=93%, 117179-EP2292227A2, 117179-EP2298776A1, C-23129, I06-2213, Q-200706, SR-01000763803-2, SR-01000763803-3, SR-01000763803-4, I14-38736, beta-Carotene, Type I, synthetic, >=93% (UV), powder, UNII-N53I4V2IA6 component OENHQHLEOONYIE-JLTXGRSLSA-N, 89648336-F9B2-44A0-9BF8-62E73369CB9B, Beta Carotene, United States Pharmacopeia (USP) Reference Standard, beta-Carotene, Type II, synthetic, >=95% (HPLC), crystalline, 3,7,12,16-tetramethyl-1,18-bis-(2,2,6-trimethyl-cyclohexyl)-octadecane, beta-Carotene, Pharmaceutical Secondary Standard; Certified Reference Material, (1E,3E,5E,7E,9E,11E,13E,15E,17E)-1,18-bis(2,6,6-trimethylcyclohex-1-enyl)-3,7, 12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene, (all-E)-1,1'-(3,7,12,16-Tetramethyl-1,3,5, 7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6, 6-trimethylcyclohexene], 1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene, 1,18-Bis(2,6,6-trimethyl-1-cyclohexenyl)-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonene

ID: 77
InChIKey: WIIZWVCIJKGZOK-RKDXNWHRSA-N
SMILES: C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 77



CID is 5959
synonyms found at PubChem are:
chloramphenicol, Chloromycetin, 56-75-7, Chlornitromycin, Levomycetin, Chlorocid, Halomycetin, Levomicetina, Alficetyn, Fenicol, Globenicol, Chloroamphenicol, Aquamycetin, Chloramex, Chlorocol, Detreomycin, Oleomycetin, Chloramficin, Chloramfilin, Chloroptic, Cloramicol, D-Chloramphenicol, Embacetin, Enteromycetin, Juvamycetin, Leukomycin, Sificetina, Anacetin, Chlomin, Mychel, Chloramphenicolum, Chloronitrin, Ciplamycetin, Detreomycine, Dextromycetin, Intramycetin, Laevomycetinum, Levomitsetin, Mediamycetine, Micochlorine, Novophenicol, Stanomycetin, Amphenicol, Amphicol, Amseclor, Austracil, Austracol, Biocetin, Biophenicol, Chemicetin, Chemicetina, Chlomycol, Chloramsaar, Chlorasol, Chloricol, Chlorocaps, Chlorocide, Chlorovules, Cidocetine, Cloramficin, Cloramidina, Clorocyn, Cloromisan, Clorosintex, Comycetin, Cylphenicol, Doctamicina, Econochlor, Erbaplast, Farmicetina, Hortfenicol, Isicetin, Ismicetina, Isophenicol, Kemicetina, Kemicetine, Leukomyan, Loromisin, Mastiphen, Medichol, Micloretin, Micoclorina, Microcetina, Novomycetin, Ophthochlor, Pantovernil, Rivomycin, Ambofen, Catilan, Desphen, Emetren, Enicol, Ertilen, Glorous, Kamaver, Klorita, Paraxin, Isopto fenicol, Chlora-tabs, Chlorocidin C, Chloroject L, Normimycin V, Chlorocid S, Klorocid S, Mychel-Vet, Chloramfenikol, Cloramfenicol, Novochlorocap, Sintomicetina, Synthomycetin, Chloromax, Oftalent, Otachron, Pentamycetin, Quemicetina, Romphenil, Ronphenil, Septicol, Chloro-25 vetag, Mycinol, Opclor, Otophen, Sintomicetine R, Sno-Phenicol, Chlorocidin C tetran, Cloroamfenicolo, Veticol, D-(-)-Chloramphenicol, Chloromycetny, Cloramfenicolo, Synthomycetine, Treomicetina, Chlorofair, Optomycin, Syntomycin, Tevcocin, Tifomycine, Unimycetin, Viceton, Cloranfenicol, Kloramfenikol, Tiromycetin, Cloramfen, Leukamycin, Loromisan, Tifomycin, CAF (pharmaceutical), Ak-chlor, Chloramfenikol [Czech], Chloromycetny [Polish], D-(-)-threo-Chloramphenicol, Cloramfenicolo [DCIT], Tega-Cetin, Chlorbiotic (Veterinary), I 337A, Cloroamfenicolo [Italian], Chloramphenicol crystalline, Elase-Chloromycetin, Chloramphenicol, d-, U-6062, NCI-C55709, NSC 3069, Chloroptic S.O.P., Cloramfenicol [INN-Spanish], Chloramphenicolum [INN-Latin], Chemiceticol, Cloramical, Cloromissan, D-threo-Chloramphenicol, Duphenicol, Interomycetine, Intramyctin, Loromicetina, Ophtochlor, Synthomycine, Chlorsig, Ronfenil, Tevcosin, Myscel, Opelor, Chlormycetin R, F armicetina, Ch loramex, Sno Phenicol, Vice ton, Tea-Cetin, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, D(-)-threo-Chloramphenicol, Econochlor (TN), CAF, Chloromyxin, Amphicol (TN), Chloromycetin (TN), C11H12Cl2N2O5, CCRIS 3922, UNII-66974FR9Q1, CHEBI:17698, Chloramphenicol [INN:BAN:JAN], D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol, HSDB 3027, NSC3069, CHLOROPTIC S.O.P, EINECS 200-287-4, NSC 16331, D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol, BRN 2225532, C.A.F, 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, AI3-25003, D-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide, Chloramphenicol (Chloromycetin), D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, WIIZWVCIJKGZOK-RKDXNWHRSA-N, D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, 2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, 66974FR9Q1, NCGC00091011-05, D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DSSTox_CID_265, D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-N-(1,1'-Dihydroxy-1-p-nitrophenylisopropyl)dichloroacetamide, 2,2-Dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide, DSSTox_RID_75473, DSSTox_GSID_20265, Mycochlorin, Ocuphenicol, Chlorocin, Levocin, Levoplast, Levosin, Levovetin, Myclocin, Soluthor, ACETAMIDE, 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-, CLM, Chloramphenicole, D(-)-threo-2-dichloroacetamido-1-p-nitrophenyl-propanediol, D(-)-threo-2-dichloroacetamido-1-p-nitrophen yl-propanediol, D(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, (-)-chloramphenicol, Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-4-nitrophenethyl]acetamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2,2-dichloroace tamide, Ophthocort (Salt/Mix), Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (theta-(theta,theta))-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-beta-(4-nitrophenyl)ethyl]acetamide, SMR000471851, Chloromyxin (Salt/Mix), CHLORAMPHENICOL LEVO, SR-01000761450, Elase-Chloromycetin (Salt/Mix), chioramphenicol, chlorocidin, cloramphenicol, D-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, CAS-56-75-7, Kemicetine (TN), Silmycetin (TN), Tifomycine (TN), Vernacetin (TN), Alficetyn (TN), Cedoctine (TN), Chloramex (TN), Nevimycin (TN), NCGC00094620-01, Biomicin (TN), Brochlor (TN), Chlorsig (TN), Phenicol (TN), Thiamphenicol,(S), D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl))-p-nitrophenethylacetamide, D-(-)-threo-2,2-Dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)]-p-nitrophenethylacetamide, Laevomycetin (TN), Synthomycine (TN), Fenicol (TN), Medicom (TN), Renicol (TN), Veticol (TN), Golden Eye (TN), Orchadexoline (TN), Chloramphenicol [USP:INN:BAN:JAN], Chloramphenicol,(S), Isoptophenicol (TN), Oftan Chlora (TN), Chlornitromycin (TN), Chloromycetin&#174, Dispersadron C (TN), PubChem20321, CHLOROMYCETIN(R), Prestwick3_000031, CHEMBL130, D0X6IU, Epitope ID:114066, AC1L1LI3, Optrex Infected Eyes (TN), SCHEMBL16111, BSPBio_000121, WLN: WNR DYQY1QMVYGG, 4-13-00-02742 (Beilstein Handbook Reference), Chloramphenicol & VRC3375, D-2-DICHLOROACETAMIDO-1-p-NITRO-PHENYL-1,3-PROPANEDIOL, MLS001055372, MLS001066397, MLS001332385, MLS001332386, MLS002222155, ARONIS23913, BIDD:GT0145, DivK1c_000544, BPBio1_000135, D-(-)-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, D-(-)-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DTXSID7020265, BDBM23447, Chloramphenicol, gamma-irradiated, CTK4B4374, HMS501L06, KBio1_000544, KS-00000XTX, BBC/192, BIC0113, MolPort-001-794-646, NINDS_000544, ZX-AFC000642, Chloramphenicol (JP15/USP/INN), Chloramphenicol (JP17/USP/INN), HMS2090M15, HMS2095G03, HMS2269N06, HMS3712G03, ZINC113382, Chloramphenicol, >=98% (HPLC), 2787-09-9, Acetamide, 2,2-dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, Acetamide, 2,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, BCP12150, D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, HY-B0239, NSC-3069, RKL10087, Tox21_111306, Tox21_400061, LS-225, MFCD00078159, s1677, SBB057728, AKOS005111001, AB02994, CCG-220031, CS-2207, DB00446, MCULE-7778960570, IDI1_000544, KS-000048O2, SMP1_000065, NCGC00091011-01, NCGC00091011-02, NCGC00091011-03, NCGC00091011-04, NCGC00091011-06, NCGC00091011-08, NCGC00091011-09, 85666-84-8, AK174225, AN-23562, AS-14683, CC-25647, CPD000471851, M163, NCI60_002620, SAM002589931, SC-18476, ST024743, AB0015087, AB1009524, Chloramphenicol, puriss., 98.0-102.0%, AB00374860, Chloramphenicol 10 microg/mL in Acetonitrile, Chloramphenicol, tested according to Ph.Eur., FT-0602995, Chloramphenicol 100 microg/mL in Ethylacetate, C-3307, C00918, D00104, W-2830, AB00374860-13, AB00374860-14, AB00374860_15, Chloramphenicol, meets USP testing specifications, C-19742, Chloramphenicol, VETRANAL(TM), analytical standard, SR-01000761450-2, SR-01000761450-3, SR-01000761450-5, BRD-K08111712-001-02-7, BRD-K08111712-001-16-7, Chloramphenicol, Antibiotic for Culture Media Use Only, Alficetyn, Chlornitromycin, Chloromycetin, Chloramphenicol, Chloramphenicol, BioReagent, suitable for plant cell culture, Chloramphenicol, certified reference material, TraceCERT(R), Chloramphenicol, British Pharmacopoeia (BP) Reference Standard, Chloramphenicol, European Pharmacopoeia (EP) Reference Standard, Chloramphenicol, United States Pharmacopeia (USP) Reference Standard, D-(-)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-N-dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propane-diol, CHLORAMPHENICOL (SEE ALSO CHLORAMPHENICOL NA SUCCINATE 982-57-0), D-( -)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL, 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propyl]acetamide, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl], Chloramphenicol, Biotechnology Performance Certified, suitable for plant cell culture, D-(-)-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxy-methyl)-p-nitrophenethyl]acetamide, 137731-90-9, 15313-32-3, 2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(hydroxy(oxido)amino)phenyl)ethyl)acetamide, (1R, 2R)-, 55172-72-0, 59112-59-3, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R*,R*)-(+-)-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-,D-(-)-threo-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]-, [R-(R*,R*)]-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-,D-(-)-threo-, Acetamide,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, D-(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE, D-(-)-threo-alpha, alpha-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE

ID: 130
InChIKey: AHLHZSCENKUUSF-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 130



CID is 5397276
synonyms found at PubChem are:
7-hydroxy-3-(2-methoxyphenyl)-4H-chromen-4-one, 63909-40-0, 7-hydroxy-2'-methoxyisoflavone, 7-hydroxy-3-(2-methoxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-3-(2-methoxyphenyl)-, EN300-37034, KBio2_001215, Spectrum_000735, SpecPlus_000115, Spectrum2_000598, Spectrum3_000688, Spectrum4_001613, Spectrum5_000365, AC1NU9H2, Oprea1_731203, BSPBio_002415, KBioGR_001985, KBioSS_001215, SPECTRUM201309, DivK1c_006211, SCHEMBL234467, SPBio_000476, AC1Q450X, CHEMBL575073, CTK2A7983, KBio1_001155, KBio2_003783, KBio2_006351, KBio3_001635, DTXSID80419858, AHLHZSCENKUUSF-UHFFFAOYSA-N, CHEBI:108602, MolPort-000-424-538, ALBB-017540, BB_NC-03144, ZINC5729882, ZX-AN016227, BBL034746, CCG-39150, SBB042190, STK888282, AKOS000270914, 7-HYDROXY-2;-METHOXYISOFLAVONE, MCULE-3582068908, NCGC00095822-01, NCGC00095822-02, NCGC00178663-01, R2592, ST50039226, 7-hydroxy-3-(2-methoxy-phenyl)-chromen-4-one, AB00052652-03, BRD-K09203354-001-02-4, F0850-4769

ID: 1595
InChIKey: OJGDCBLYJGHCIH-UHFFFAOYSA-N
SMILES: CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 1595



CID is 2442
synonyms found at PubChem are:
bromhexine, 3572-43-8, Bromhexinum, Bromhexina, Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, Bromexine, Bromhexine [INN:BAN], Bromhexinum [INN-Latin], Bromhexina [INN-Spanish], Bromhexine Monohydrochloride, UNII-Q1J152VB1P, 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline, C14H20Br2N2, EINECS 222-684-1, Q1J152VB1P, CHEBI:77032, OJGDCBLYJGHCIH-UHFFFAOYSA-N, N-Cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amin, 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline, 3,5-Dibromo-Nalpha-cyclohexyl-Nalpha-methyltoluene-alpha-2-diamine, NA 274, NA-274, Toluene-.alpha.,2-diamine, 3,5-dibromo-N.alpha.-cyclohexyl-N.alpha.-methyl-, [(2-amino-3,5-dibromophenyl)methyl]cyclohexylmethylamine, 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline, Flegamin, SMR001826324, Tauglicolo, Bromexina, Fluibron, Fluibron (TN), Bromhexine (INN), Spectrum_001392, AC1L1DOQ, Spectrum2_001526, Spectrum3_001152, Spectrum4_000758, Spectrum5_001054, Oprea1_147116, SCHEMBL19059, BSPBio_002703, KBioGR_001116, KBioSS_001872, MLS004774079, MLS006011815, DivK1c_000455, SPBio_001312, CHEMBL253376, DTXSID6022686, CTK5I6419, KBio1_000455, KBio2_001872, KBio2_004440, KBio2_007008, KBio3_002203, OJGDCBLYJGHCIH-UHFFFAOYSA-, MolPort-000-887-467, NINDS_000455, HMS2090K17, ZINC608220, 611-75-6 (mono-hydrochloride), BBL022746, MFCD00436295, SBB021209, STK177356, AKOS000305902, ACM3572438, API0007117, DB09019, MCULE-1869883185, IDI1_000455, NCGC00178520-01, NCGC00178520-02, NCGC00178520-05, AJ-23700, AK129825, Q563, ST024771, SBI-0051773.P002, AX8118823, KB-225470, LS-174556, D07542, EN300-228940, AB00053644-02, AB00053644_03, AB00053644_04, BRD-K47631482-003-02-1, BRD-K47631482-003-03-9, F2173-0412, N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 2,4-Dibromo-6-([cyclohexyl(methyl)amino]methyl)aniline #, 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemathanamine, N-2-AMINO-3,5-DIBROMOBENZYL-N-CYCLOHEXYLMETHYLAMINE, 2,4-Dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline (HCl), 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl benzenemethanamine, N-(2-AMINO-3,5-DIBROMOBENZYL)-N-CYCLOHEXYL-N-METHYLAMINE, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine, InChI=1/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17/h7-8,12H,2-6,9,17H2,1H3

ID: 1086
InChIKey: JLZAERUVCODZQO-UGOWOXHDSA-N
SMILES: CC(=O)OC1CC[C@@]2(C3CC[C@@]4(C(CC[C@@]4(C3CC[C@@]2(C1)O)O)C5=CC(=O)OC5)C)C=O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 1086



CID is 44135347
synonyms found at PubChem are:
ACETYL STROPHANIDIN

ID: 72
InChIKey: TZFWDZFKRBELIQ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1Cl)NC(=O)O2

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 72



CID is 2733
synonyms found at PubChem are:
chlorzoxazone, 95-25-0, Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone, Biomioran, Escoflex, Myoflexin, Myoflexine, Pathorysin, Mioran, Miotran, Neoflex, Solaxin, 2(3H)-Benzoxazolone, 5-chloro-, Parafon Forte DSC, 5-Chloro-2-hydroxybenzoxazole, 5-Chloro-2-benzoxazolinone, Chlorzoxane, 5-Chlorobenzoxazolidone, 5-Chloro-2(3H)-benzoxazolone, Usaf ma-10, 5-Chlorobenzoxazol-2-one, Strifon Forte Dsc, Chlorzoxazonum, 5-Chloro-2-benzoxazolol, 5-Chlorobenzoxazolone, 2-Hydroxy-5-chlorobenzoxazole, 5-Chlorobenzo[d]oxazol-2(3H)-one, Chlorsoxazone, Clorzoxazona, Klorzoxazon, Remofleks, Nyoflex, 5-Chlorbenzoxazolin-2-on, Parafon Forte, 5-Chloro-1,3-benzoxazol-2(3H)-one, 5-chloro-3H-1,3-benzoxazol-2-one, Parafon, 5-Chloro-3(H)-2-benzoxazolone, 5-Chlorobenzoksazolon-2, 5-Chlorobenzoksazolinon-2, 5-chlorobenzoxazolin-2-one, Chlorzoxazonum [INN-Latin], Clorzoxazona [INN-Spanish], chlorzoxazona, Relaxazone, Remular, C7H4ClNO2, 5-Chlorobenzoksazolon-2 [Polish], Remular-S, 5-Chlorobenzoksazolinon-2 [Polish], UNII-H0DE420U8G, 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one, NSC 26189, 2-BENZOXAZOLINONE, 5-CHLORO-, Paraflex (TN), 5-chlorobenzo[d]oxazol-2-ol, Chlorzoxazone [INN:BAN:JAN], 5-chloro-3H-benzooxazol-2-one, 5-chloro-1,3-benzoxazol-2-ol, EZE-DS, EINECS 202-403-9, component of Parafon Forte, CHEMBL1371, AI3-63119, MLS000069380, CHEBI:3655, Chlorzoxazone (JAN/USP/INN), H0DE420U8G, TZFWDZFKRBELIQ-UHFFFAOYSA-N, CAS-95-25-0, NCGC00015238-02, SMR000058269, DSSTox_CID_2813, C 4397, DSSTox_RID_76739, DSSTox_GSID_22813, CLW, 5-chloro-3-hydrobenzoxazol-2-one, Lorzone, SR-01000075207, Clorzoxazone, Phantom, Stealth, Strifon, 5-Chloro-3H-benzoxazol-2-one, Mystox MP, Prestwick_62, Chlorzoxazone,(S), Chlorzoxazone [USP:INN:BAN:JAN], Citrex (acaricide), Muscol (TN), Parafon Forte (TN), PubChem8642, 5-Chlorobenzoxazolinone, Spectrum_000148, AC1L1ECE, Opera_ID_1659, Prestwick0_000163, Prestwick1_000163, Prestwick2_000163, Prestwick3_000163, Spectrum2_001149, Spectrum3_000350, Spectrum4_000287, Spectrum5_000745, Lopac-C-4397, D08ZEB, 5-Chloro-benzooxazol-2-ol, AC1Q3KM0, AC1Q3KM1, Ortho Brand of Chlorzoxazone, 5-chloro-benzoxazolin-2-one, Lopac0_000253, SCHEMBL35177, BSPBio_000025, BSPBio_002019, KBioGR_000814, KBioSS_000628, WLN: T56 BMVOJ HG, McNeil Brand of Chlorzoxazone, DivK1c_000895, SPECTRUM1500188, SPBio_001077, SPBio_001946, BPBio1_000029, GTPL2322, DTXSID9022813, CTK6H1680, HMS502M17, KBio1_000895, KBio2_000628, KBio2_003196, KBio2_005764, KBio3_001239, KS-00000VVL, MolPort-001-759-947, MolPort-006-110-468, NINDS_000895, HMS1568B07, HMS1920O07, HMS2091E14, HMS2095B07, HMS2235I19, HMS3259I15, HMS3260D08, HMS3373P17, HMS3652K22, HMS3712B07, Pharmakon1600-01500188, Secure 360SC Insecticide-Miticide, ACT08248, ALBB-012641, BCP07916, HY-B1462, NSC26189, STR00805, Tox21_110105, Tox21_500253, BBL003952, BDBM50290811, CCG-40323, KM3336, MFCD00005717, NSC-26189, NSC756693, s4155, SBB003864, STK071582, ZINC84843283, AKOS000404381, Tox21_110105_1, component of Parafon Forte (Salt/Mix), CS-5155, DB00356, HG-0202, LP00253, MCULE-3638156868, NC00499, NSC-756693, 5-chloranyl-3H-1,3-benzoxazol-2-one, 5-chloro-1,3-benzoxazole-2(3H)-one, IDI1_000895, Chlorzoxazone 1.0 mg/ml in Acetonitrile, NCGC00015238-01, NCGC00015238-03, NCGC00015238-04, NCGC00015238-05, NCGC00015238-06, NCGC00015238-07, NCGC00015238-08, NCGC00015238-09, NCGC00015238-10, NCGC00015238-13, NCGC00093714-01, NCGC00093714-02, NCGC00093714-03, NCGC00093714-04, NCGC00260938-01, 5-Chloro-1,3-benzoxazol-2(3H)-one #, AC-12192, AN-24309, BP-11613, CPD000058269, KB-88347, LS-42267, SAM002554888, SC-07433, SBI-0050241.P004, AB0011060, AB1004047, ST2406217, AB00051947, AC 303-630, EU-0100253, FT-0620220, ST45024437, EN300-31026, 5-Chloro-2,3-dihydro-2-oxo-1,3-benzoxazole, C07931, D00771, AB00051947_05, AB00051947_06, A845253, I14-4579, SR-01000075207-1, SR-01000075207-3, SR-01000075207-5, W-100168, BRD-K98174813-001-05-7, BRD-K98174813-001-08-1, Z57183224, 5-Chloro-2(3H)-benzoxazolone; 5-Chloro-2-hydroxybenzoxazole, Chlorzoxazone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10, 32850-84-3

ID: 610
InChIKey: FMOKUKPRJSMPOI-UHFFFAOYSA-N
SMILES: CC(=O)CC1CCCCN1.Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 610



CID is 16667749
synonyms found at PubChem are:
PELLETIERINE HYDROCHLORIDE, 5984-61-2, Isopelletierine hydrochloride, Pelletierine hydrochloride [MI], (+/-)-Pelletierine hydrochloride, Pelletierine hydrochloride, (+/-)-, SPECTRUM300553, SCHEMBL4270933, 2-Propanone, 1-(2-piperidinyl)-, hydrochloride (1:1), CHEMBL3039396, CTK1E6396, CCG-38558, NCGC00095603-01, 2-Propanone, 1-(2-piperidinyl)-, hydrochloride, SR-05000002412, SR-05000002412-1

ID: 53
InChIKey: NIDUTZAIIODVCH-FHNSGPDVSA-N
SMILES: CCC(C)C(C(=O)O[C@H]1[C@@H](C(C(=C)C2([C@@]1([C@@H](CC2=O)C3=COC=C3)C)O)[C@]4([C@H](CC(=O)O[C@](C4CC(=O)OC)(C)COC(=O)C)OC(=O)C)C)OC=O)OC(=O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 53



CID is 6710640
synonyms found at PubChem are:
PRIEURANIN ACETATE, KBio2_006186, Spectrum_000570, AC1O8JTI, Spectrum2_000243, Spectrum3_000024, Spectrum4_001305, Spectrum5_000089, BSPBio_001687, KBioGR_001709, KBioSS_001050, SPECTRUM100069, SPBio_000026, KBio2_001050, KBio2_003618, KBio3_000807, CHEBI:110188, CCG-39804, SDCCGMLS-0066356.P001, NCGC00179087-01, BRD-A64374397-001-02-6, [(3S,3aR,4R,5R)-6-[(2S,4R,5S)-5-acetyloxy-2-(acetyloxymethyl)-3-(2-methoxy-2-oxoethyl)-2,4-dimethyl-7-oxooxepan-4-yl]-5-formyloxy-3-(furan-3-yl)-7a-hydroxy-3a-methyl-7-methylidene-1-oxo-3,4,5,6-tetrahydro-2H-inden-4-yl] 2-acetyloxy-3-methylpentanoate

ID: 517
InChIKey: DTFARBHXORYQBF-ORYQWCPZSA-N
SMILES: CC(C)[C@@H]1CC2=C(O1)C=CC3=C2O[C@H]4COC5=CC(=C(C=C5[C@H]4C3=O)OC)OC

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 517



CID is 73068
synonyms found at PubChem are:
Dihydrorotenone, (2s,6ar,12ar)-8,9-dimethoxy-2-(propan-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6ah)-one, Caswell No. 353, Dihydrorotenone (VAN), 1',2'-Dihydrorotenone, Rotenone, dihydro- (VAN), NSC 53866, EPA Pesticide Chemical Code 071002, NSC 351138, AC1L2J7Q, AC1Q6KP8, CTK5C4931, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6a-alphah)-one, 1,2,12,12a-alpha-tetrahydro-2-alpha-isopropyl-8,9-dimethoxy-, LS-39365, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropyl-8,9-dimethoxy-, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-, (2R-(2alpha,6aalpha,12aalpha))-

ID: 2348
InChIKey: VLPIATFUUWWMKC-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)OCC(C)N

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 2348



CID is 4178
synonyms found at PubChem are:
Mexiletine, 31828-71-4, 1-(2,6-dimethylphenoxy)propan-2-amine, Mexiletina, Mexitil, Mexiletinum, Mexilitine, Mexiletinum [INN-Latin], Mexiletina [INN-Spanish], Mexiletene, Mexityl, Mexiletine [INN:BAN], 2-Propanamine, 1-(2,6-dimethylphenoxy)-, Mexiletine HCL, 1-Methyl-2-(2,6-xylyloxy)ethylamine, Mexiletine (INN), 1-(2,6-Dimethylphenoxy)-2-propanamine, ETHYLAMINE, 1-METHYL-2-(2,6-XYLYLOXY)-, 2-(2-aminopropoxy)-1,3-dimethylbenzene, KOE-1173, EINECS 250-825-7, KO1173, CHEMBL558, KO-1173, BRN 2092205, CHEBI:6916, 1-(2',6'-Dimethylphenoxy)-2-aminopropane, VLPIATFUUWWMKC-UHFFFAOYSA-N, 1-methyl-2-(2,6-xylyloxy)ethanamine, 1-(2,6-Dimethylphenoxy)-2-aminopropane, 1-(2,6-Dimethylphenoxy)-2-amino propane, Mexitil (TN), (+-)-1-(2,6-dimethylphenoxy)propan-2-amine, (2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane, 180966-61-4, 2-(2-Aminopropoxy)-1,3-DiMethyl-Benzene Hydrochloride, 1-(2,6-Xylyloxy)-2-aminopropane, 1-(2',6'-dimethyl-phenoxy)-2-amino-propane, NCGC00015659-06, dl-mexiletine, mexiletin HCl, (RS)-Mexiletine, Mexitil (Salt/Mix), (+/-)-Mexiletine, mexiletin hydrochloride, Spectrum_001602, Prestwick0_000241, Prestwick1_000241, Prestwick2_000241, Prestwick3_000241, Spectrum3_000727, Spectrum4_000795, Spectrum5_001279, D0X0RI, AC1L1HL7, AC1Q2BC5, AC1Q2BC6, Lopac0_000784, SCHEMBL16081, BSPBio_000022, BSPBio_002254, KBioGR_001270, KBioSS_002082, DivK1c_000834, SPBio_002241, BPBio1_000026, GTPL2629, DTXSID8048446, 5370-01-4 (hydrochloride), CTK4D7767, KBio1_000834, KBio2_002082, KBio2_004650, KBio2_007218, KBio3_001474, MolPort-001-790-944, NINDS_000834, Mexiletine hydrochloride (Salt/Mix), BDBM50117271, SBB070242, AKOS015890265, CCG-204869, DB00379, MCULE-1930292316, NE17727, 1-(2,6-dimethylphenoxy)prop-2-ylamine, IDI1_000834, NCGC00015659-02, NCGC00015659-03, NCGC00015659-04, NCGC00015659-05, NCGC00015659-07, NCGC00015659-08, NCGC00015659-09, NCGC00015659-10, NCGC00015659-11, NCGC00162253-01, NCGC00162253-02, 1-(2,6-dimethylphenoxy)-2-propanolamine, 2-Amino-1-(2,6-dimethylphenoxy)propane, 2-Propanamine,1-(2,4-dimethylphenoxy)-, AN-12179, BC205702, KB-55046, LS-68257, O654, SC-50523, SBI-0050762.P003, 2-(2,6-dimethylphenoxy)-1-methylethylamine, AB00053683, FT-0605484, FT-0658952, 2-(2,6-dimethylphenoxy)-1-methyl-ethylamine, EN300-54300, 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine, C07220, D08215, AB00053683_10, AB00053683_11, 828M714, I01-6374, W-106874, BRD-A64092382-003-04-3, BRD-A64092382-003-09-2, Z818727398, 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine(Mexiletine)