previous compound ID: 72 next compound
InChIKey: TZFWDZFKRBELIQ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1Cl)NC(=O)O2

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 55
"KA Teske" "GW Carlile" "Y Luo" "DY Thomas" "D Zhang" "R Robert" "JW Hanrahan"
ReferenceID: 53
"GW Carlile" "E Matthes" "D Rotin" "B Kus" "J Liao" "DY Thomas" "R Robert" "SD Macknight" "J Goepp" "JW Hanrahan"

chemical graph of compound 72





CID is 2733
synonyms found at PubChem are:
chlorzoxazone, 95-25-0, Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone, Biomioran, Escoflex, Myoflexin, Myoflexine, Pathorysin, Mioran, Miotran, Neoflex, Solaxin, 2(3H)-Benzoxazolone, 5-chloro-, Parafon Forte DSC, 5-Chloro-2-hydroxybenzoxazole, 5-Chloro-2-benzoxazolinone, Chlorzoxane, 5-Chlorobenzoxazolidone, 5-Chloro-2(3H)-benzoxazolone, Usaf ma-10, 5-Chlorobenzoxazol-2-one, Strifon Forte Dsc, Chlorzoxazonum, 5-Chloro-2-benzoxazolol, 5-Chlorobenzoxazolone, 2-Hydroxy-5-chlorobenzoxazole, 5-Chlorobenzo[d]oxazol-2(3H)-one, Chlorsoxazone, Clorzoxazona, Klorzoxazon, Remofleks, Nyoflex, 5-Chlorbenzoxazolin-2-on, Parafon Forte, 5-Chloro-1,3-benzoxazol-2(3H)-one, 5-chloro-3H-1,3-benzoxazol-2-one, Parafon, 5-Chloro-3(H)-2-benzoxazolone, 5-Chlorobenzoksazolon-2, 5-Chlorobenzoksazolinon-2, 5-chlorobenzoxazolin-2-one, Chlorzoxazonum [INN-Latin], Clorzoxazona [INN-Spanish], chlorzoxazona, Relaxazone, Remular, C7H4ClNO2, 5-Chlorobenzoksazolon-2 [Polish], Remular-S, 5-Chlorobenzoksazolinon-2 [Polish], UNII-H0DE420U8G, 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one, NSC 26189, 2-BENZOXAZOLINONE, 5-CHLORO-, Paraflex (TN), 5-chlorobenzo[d]oxazol-2-ol, Chlorzoxazone [INN:BAN:JAN], 5-chloro-3H-benzooxazol-2-one, 5-chloro-1,3-benzoxazol-2-ol, EZE-DS, EINECS 202-403-9, component of Parafon Forte, CHEMBL1371, AI3-63119, MLS000069380, CHEBI:3655, Chlorzoxazone (JAN/USP/INN), H0DE420U8G, TZFWDZFKRBELIQ-UHFFFAOYSA-N, CAS-95-25-0, NCGC00015238-02, SMR000058269, DSSTox_CID_2813, C 4397, DSSTox_RID_76739, DSSTox_GSID_22813, CLW, 5-chloro-3-hydrobenzoxazol-2-one, Lorzone, SR-01000075207, Clorzoxazone, Phantom, Stealth, Strifon, 5-Chloro-3H-benzoxazol-2-one, Mystox MP, Prestwick_62, Chlorzoxazone,(S), Chlorzoxazone [USP:INN:BAN:JAN], Citrex (acaricide), Muscol (TN), Parafon Forte (TN), PubChem8642, 5-Chlorobenzoxazolinone, Spectrum_000148, AC1L1ECE, Opera_ID_1659, Prestwick0_000163, Prestwick1_000163, Prestwick2_000163, Prestwick3_000163, Spectrum2_001149, Spectrum3_000350, Spectrum4_000287, Spectrum5_000745, Lopac-C-4397, D08ZEB, 5-Chloro-benzooxazol-2-ol, AC1Q3KM0, AC1Q3KM1, Ortho Brand of Chlorzoxazone, 5-chloro-benzoxazolin-2-one, Lopac0_000253, SCHEMBL35177, BSPBio_000025, BSPBio_002019, KBioGR_000814, KBioSS_000628, WLN: T56 BMVOJ HG, McNeil Brand of Chlorzoxazone, DivK1c_000895, SPECTRUM1500188, SPBio_001077, SPBio_001946, BPBio1_000029, GTPL2322, DTXSID9022813, CTK6H1680, HMS502M17, KBio1_000895, KBio2_000628, KBio2_003196, KBio2_005764, KBio3_001239, KS-00000VVL, MolPort-001-759-947, MolPort-006-110-468, NINDS_000895, HMS1568B07, HMS1920O07, HMS2091E14, HMS2095B07, HMS2235I19, HMS3259I15, HMS3260D08, HMS3373P17, HMS3652K22, HMS3712B07, Pharmakon1600-01500188, Secure 360SC Insecticide-Miticide, ACT08248, ALBB-012641, BCP07916, HY-B1462, NSC26189, STR00805, Tox21_110105, Tox21_500253, BBL003952, BDBM50290811, CCG-40323, KM3336, MFCD00005717, NSC-26189, NSC756693, s4155, SBB003864, STK071582, ZINC84843283, AKOS000404381, Tox21_110105_1, component of Parafon Forte (Salt/Mix), CS-5155, DB00356, HG-0202, LP00253, MCULE-3638156868, NC00499, NSC-756693, 5-chloranyl-3H-1,3-benzoxazol-2-one, 5-chloro-1,3-benzoxazole-2(3H)-one, IDI1_000895, Chlorzoxazone 1.0 mg/ml in Acetonitrile, NCGC00015238-01, NCGC00015238-03, NCGC00015238-04, NCGC00015238-05, NCGC00015238-06, NCGC00015238-07, NCGC00015238-08, NCGC00015238-09, NCGC00015238-10, NCGC00015238-13, NCGC00093714-01, NCGC00093714-02, NCGC00093714-03, NCGC00093714-04, NCGC00260938-01, 5-Chloro-1,3-benzoxazol-2(3H)-one #, AC-12192, AN-24309, BP-11613, CPD000058269, KB-88347, LS-42267, SAM002554888, SC-07433, SBI-0050241.P004, AB0011060, AB1004047, ST2406217, AB00051947, AC 303-630, EU-0100253, FT-0620220, ST45024437, EN300-31026, 5-Chloro-2,3-dihydro-2-oxo-1,3-benzoxazole, C07931, D00771, AB00051947_05, AB00051947_06, A845253, I14-4579, SR-01000075207-1, SR-01000075207-3, SR-01000075207-5, W-100168, BRD-K98174813-001-05-7, BRD-K98174813-001-08-1, Z57183224, 5-Chloro-2(3H)-benzoxazolone; 5-Chloro-2-hydroxybenzoxazole, Chlorzoxazone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10, 32850-84-3