previous compound ID: 77 next compound
InChIKey: WIIZWVCIJKGZOK-RKDXNWHRSA-N
SMILES: C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53
"J Goepp" "JW Hanrahan" "B Kus" "R Robert" "J Liao" "DY Thomas" "D Rotin" "SD Macknight" "GW Carlile" "E Matthes"
ReferenceID: 55
"JW Hanrahan" "R Robert" "DY Thomas" "GW Carlile" "Y Luo" "KA Teske" "D Zhang"

chemical graph of compound 77





CID is 5959
synonyms found at PubChem are:
chloramphenicol, Chloromycetin, 56-75-7, Chlornitromycin, Levomycetin, Chlorocid, Halomycetin, Levomicetina, Alficetyn, Fenicol, Globenicol, Chloroamphenicol, Aquamycetin, Chloramex, Chlorocol, Detreomycin, Oleomycetin, Chloramficin, Chloramfilin, Chloroptic, Cloramicol, D-Chloramphenicol, Embacetin, Enteromycetin, Juvamycetin, Leukomycin, Sificetina, Anacetin, Chlomin, Mychel, Chloramphenicolum, Chloronitrin, Ciplamycetin, Detreomycine, Dextromycetin, Intramycetin, Laevomycetinum, Levomitsetin, Mediamycetine, Micochlorine, Novophenicol, Stanomycetin, Amphenicol, Amphicol, Amseclor, Austracil, Austracol, Biocetin, Biophenicol, Chemicetin, Chemicetina, Chlomycol, Chloramsaar, Chlorasol, Chloricol, Chlorocaps, Chlorocide, Chlorovules, Cidocetine, Cloramficin, Cloramidina, Clorocyn, Cloromisan, Clorosintex, Comycetin, Cylphenicol, Doctamicina, Econochlor, Erbaplast, Farmicetina, Hortfenicol, Isicetin, Ismicetina, Isophenicol, Kemicetina, Kemicetine, Leukomyan, Loromisin, Mastiphen, Medichol, Micloretin, Micoclorina, Microcetina, Novomycetin, Ophthochlor, Pantovernil, Rivomycin, Ambofen, Catilan, Desphen, Emetren, Enicol, Ertilen, Glorous, Kamaver, Klorita, Paraxin, Isopto fenicol, Chlora-tabs, Chlorocidin C, Chloroject L, Normimycin V, Chlorocid S, Klorocid S, Mychel-Vet, Chloramfenikol, Cloramfenicol, Novochlorocap, Sintomicetina, Synthomycetin, Chloromax, Oftalent, Otachron, Pentamycetin, Quemicetina, Romphenil, Ronphenil, Septicol, Chloro-25 vetag, Mycinol, Opclor, Otophen, Sintomicetine R, Sno-Phenicol, Chlorocidin C tetran, Cloroamfenicolo, Veticol, D-(-)-Chloramphenicol, Chloromycetny, Cloramfenicolo, Synthomycetine, Treomicetina, Chlorofair, Optomycin, Syntomycin, Tevcocin, Tifomycine, Unimycetin, Viceton, Cloranfenicol, Kloramfenikol, Tiromycetin, Cloramfen, Leukamycin, Loromisan, Tifomycin, CAF (pharmaceutical), Ak-chlor, Chloramfenikol [Czech], Chloromycetny [Polish], D-(-)-threo-Chloramphenicol, Cloramfenicolo [DCIT], Tega-Cetin, Chlorbiotic (Veterinary), I 337A, Cloroamfenicolo [Italian], Chloramphenicol crystalline, Elase-Chloromycetin, Chloramphenicol, d-, U-6062, NCI-C55709, NSC 3069, Chloroptic S.O.P., Cloramfenicol [INN-Spanish], Chloramphenicolum [INN-Latin], Chemiceticol, Cloramical, Cloromissan, D-threo-Chloramphenicol, Duphenicol, Interomycetine, Intramyctin, Loromicetina, Ophtochlor, Synthomycine, Chlorsig, Ronfenil, Tevcosin, Myscel, Opelor, Chlormycetin R, F armicetina, Ch loramex, Sno Phenicol, Vice ton, Tea-Cetin, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, D(-)-threo-Chloramphenicol, Econochlor (TN), CAF, Chloromyxin, Amphicol (TN), Chloromycetin (TN), C11H12Cl2N2O5, CCRIS 3922, UNII-66974FR9Q1, CHEBI:17698, Chloramphenicol [INN:BAN:JAN], D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol, HSDB 3027, NSC3069, CHLOROPTIC S.O.P, EINECS 200-287-4, NSC 16331, D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol, BRN 2225532, C.A.F, 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, AI3-25003, D-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide, Chloramphenicol (Chloromycetin), D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, WIIZWVCIJKGZOK-RKDXNWHRSA-N, D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, 2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, 66974FR9Q1, NCGC00091011-05, D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DSSTox_CID_265, D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-N-(1,1'-Dihydroxy-1-p-nitrophenylisopropyl)dichloroacetamide, 2,2-Dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide, DSSTox_RID_75473, DSSTox_GSID_20265, Mycochlorin, Ocuphenicol, Chlorocin, Levocin, Levoplast, Levosin, Levovetin, Myclocin, Soluthor, ACETAMIDE, 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-, CLM, Chloramphenicole, D(-)-threo-2-dichloroacetamido-1-p-nitrophenyl-propanediol, D(-)-threo-2-dichloroacetamido-1-p-nitrophen yl-propanediol, D(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, (-)-chloramphenicol, Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-4-nitrophenethyl]acetamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2,2-dichloroace tamide, Ophthocort (Salt/Mix), Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (theta-(theta,theta))-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-beta-(4-nitrophenyl)ethyl]acetamide, SMR000471851, Chloromyxin (Salt/Mix), CHLORAMPHENICOL LEVO, SR-01000761450, Elase-Chloromycetin (Salt/Mix), chioramphenicol, chlorocidin, cloramphenicol, D-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, CAS-56-75-7, Kemicetine (TN), Silmycetin (TN), Tifomycine (TN), Vernacetin (TN), Alficetyn (TN), Cedoctine (TN), Chloramex (TN), Nevimycin (TN), NCGC00094620-01, Biomicin (TN), Brochlor (TN), Chlorsig (TN), Phenicol (TN), Thiamphenicol,(S), D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl))-p-nitrophenethylacetamide, D-(-)-threo-2,2-Dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)]-p-nitrophenethylacetamide, Laevomycetin (TN), Synthomycine (TN), Fenicol (TN), Medicom (TN), Renicol (TN), Veticol (TN), Golden Eye (TN), Orchadexoline (TN), Chloramphenicol [USP:INN:BAN:JAN], Chloramphenicol,(S), Isoptophenicol (TN), Oftan Chlora (TN), Chlornitromycin (TN), Chloromycetin&#174, Dispersadron C (TN), PubChem20321, CHLOROMYCETIN(R), Prestwick3_000031, CHEMBL130, D0X6IU, Epitope ID:114066, AC1L1LI3, Optrex Infected Eyes (TN), SCHEMBL16111, BSPBio_000121, WLN: WNR DYQY1QMVYGG, 4-13-00-02742 (Beilstein Handbook Reference), Chloramphenicol & VRC3375, D-2-DICHLOROACETAMIDO-1-p-NITRO-PHENYL-1,3-PROPANEDIOL, MLS001055372, MLS001066397, MLS001332385, MLS001332386, MLS002222155, ARONIS23913, BIDD:GT0145, DivK1c_000544, BPBio1_000135, D-(-)-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, D-(-)-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DTXSID7020265, BDBM23447, Chloramphenicol, gamma-irradiated, CTK4B4374, HMS501L06, KBio1_000544, KS-00000XTX, BBC/192, BIC0113, MolPort-001-794-646, NINDS_000544, ZX-AFC000642, Chloramphenicol (JP15/USP/INN), Chloramphenicol (JP17/USP/INN), HMS2090M15, HMS2095G03, HMS2269N06, HMS3712G03, ZINC113382, Chloramphenicol, >=98% (HPLC), 2787-09-9, Acetamide, 2,2-dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, Acetamide, 2,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, BCP12150, D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, HY-B0239, NSC-3069, RKL10087, Tox21_111306, Tox21_400061, LS-225, MFCD00078159, s1677, SBB057728, AKOS005111001, AB02994, CCG-220031, CS-2207, DB00446, MCULE-7778960570, IDI1_000544, KS-000048O2, SMP1_000065, NCGC00091011-01, NCGC00091011-02, NCGC00091011-03, NCGC00091011-04, NCGC00091011-06, NCGC00091011-08, NCGC00091011-09, 85666-84-8, AK174225, AN-23562, AS-14683, CC-25647, CPD000471851, M163, NCI60_002620, SAM002589931, SC-18476, ST024743, AB0015087, AB1009524, Chloramphenicol, puriss., 98.0-102.0%, AB00374860, Chloramphenicol 10 microg/mL in Acetonitrile, Chloramphenicol, tested according to Ph.Eur., FT-0602995, Chloramphenicol 100 microg/mL in Ethylacetate, C-3307, C00918, D00104, W-2830, AB00374860-13, AB00374860-14, AB00374860_15, Chloramphenicol, meets USP testing specifications, C-19742, Chloramphenicol, VETRANAL(TM), analytical standard, SR-01000761450-2, SR-01000761450-3, SR-01000761450-5, BRD-K08111712-001-02-7, BRD-K08111712-001-16-7, Chloramphenicol, Antibiotic for Culture Media Use Only, Alficetyn, Chlornitromycin, Chloromycetin, Chloramphenicol, Chloramphenicol, BioReagent, suitable for plant cell culture, Chloramphenicol, certified reference material, TraceCERT(R), Chloramphenicol, British Pharmacopoeia (BP) Reference Standard, Chloramphenicol, European Pharmacopoeia (EP) Reference Standard, Chloramphenicol, United States Pharmacopeia (USP) Reference Standard, D-(-)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-N-dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propane-diol, CHLORAMPHENICOL (SEE ALSO CHLORAMPHENICOL NA SUCCINATE 982-57-0), D-( -)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL, 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propyl]acetamide, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl], Chloramphenicol, Biotechnology Performance Certified, suitable for plant cell culture, D-(-)-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxy-methyl)-p-nitrophenethyl]acetamide, 137731-90-9, 15313-32-3, 2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(hydroxy(oxido)amino)phenyl)ethyl)acetamide, (1R, 2R)-, 55172-72-0, 59112-59-3, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R*,R*)-(+-)-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-,D-(-)-threo-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]-, [R-(R*,R*)]-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-,D-(-)-threo-, Acetamide,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, D-(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE, D-(-)-threo-alpha, alpha-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE