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CandActCFTR used public reference

The following publication reference has been reported to contain CFTR related structural information.
"B Kus" "HR de Jonge" "P Lesimple" "JW Hanrahan" "DY Thomas" "BJ Scholte" "N Liu" "M Wilke" "J Liao" "D Rotin" "H Balghi" "GW Carlile" "R Robert"


Below you will find all the structures identified in the publication. Be warned that this does not imply any activity. n=2
ID: 3
InChIKey: FJNFVCAHHFNREI-UHFFFAOYSA-N
SMILES: CC(C1=NC2=CC=CC=C2C(=N1)OC3CCCCC3)N4CCN(CC4)S(=O)(=O)C5=CC=C(C=C5)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

chemical graph of compound 3



CID is 11957831
synonyms found at PubChem are:
815592-21-3, 4-(cyclohexyloxy)-2-(1-(4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl)ethyl)quinazoline, CFcor-325, VRT-325, 4-(Cyclohexyloxy)-2-(1-(4-(4-methoxyphenylsulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl}ethyl)quinazoline, ACMC-20p1e2, GTPL4340, SCHEMBL3822809, VRT325, CHEMBL1257047, CTK9A5799, DTXSID00474707, VRT 325, MolPort-006-415-015, KS-000000GF, AKOS030228615, 4-cyclohexyloxy-2-[1-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethyl]quinazoline, KB-01359, KB-34900, A1-01884, 4-(Cyclohexyloxy)-2-(1-(4-((4-methoxyphenyl)sulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl}ethyl)quinazoline
ID: 29
InChIKey: CEUMONXVSJOJIH-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC(=CC3=NC=C2)Cl.Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

chemical graph of compound 29



CID is 3085326
synonyms found at PubChem are:
Glafenine hydrochloride, 65513-72-6, Glafenine (hydrochloride), DSSTox_CID_25497, DSSTox_RID_80916, DSSTox_GSID_45497, SR-01000473478, C19H17ClN2O4.ClH, 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate, Prestwick_628, Glafenin hydrochloride, Glafenine(hydrochloride), AC1MJ4AX, NCGC00016909-01, CAS-65513-72-6, MLS002154254, SCHEMBL970807, CHEMBL1572751, DTXSID7045497, CTK8G0041, HY-B1153A, KS-00001FBC, MolPort-004-964-888, HMS1568L08, Tox21_110678, 2430AH, AKOS024374941, Tox21_110678_1, CCG-220293, CS-6517, MCULE-3160845237, Benzoic acid, 2-((7-chloro-4-quinolinyl)amino)-, 2,3-dihydroxypropyl ester, monohydrochloride, NCGC00094881-07, SMR001233515, Glafenine hydrochloride, analytical standard, ST51015012, SR-01000473478-1, SR-01000473478-3, 2,3-dihydroxypropyl 2-(7-chloroquinolin-4-ylamino)benzoate hydrochloride, 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate, chloride, 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate hydrochloride, AKOS026749774