previous compound ID: 43 next compound
InChIKey: JIMHYXZZCWVCMI-ZSOIEALJSA-N
SMILES: C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 2
"S Zhang" "SB Hicks" "BA Woodworth" "D Skinner" "EJ Sorscher" "SM Rowe" "BT Conger"
ReferenceID: 41
"J Prasain" "JC Fulton" "LC Pyle" "S Barnes" "PA Sloane" "SM Rowe" "K Backer" "M Mazur" "JP Clancy"

chemical graph of compound 43




CID is 1554208
synonyms found at PubChem are:
CFTRinh-172, CFTR(inh)-172, CFTR Inhibitor-172, 307510-92-5, CHEMBL461939, 3-[(3-Trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone, CFTRinh 172, 4-[4-oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-(5z)-ylidenemethyl]-benzoic acid, CFinh-172, CFTR Inh-172, AC1LT95A, AOB6719, 5-[(4-Carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl-4-thiazolidinone, JIMHYXZZCWVCMI-ZSOIEALJSA-N, MolPort-000-501-417, ZINC966859, BDBM50244767, MFCD06411408, STL032754, AKOS000365470, CS-3185, BAS 00786641, HY-16671, BIM-0044592.P001, ST50148666, EC-000.1908, Z-2135, J-018109, 4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid, 4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid, 4-[4-Oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-5Z)-ylidenemethyl]-benzoic acid, (Z)-4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid, 4-({4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}met hyl)benzoic acid, 4-[(Z)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid, 4-[(Z)-{4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, 4-{[(5Z)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl}benzoic acid