previous compound ID: 44 next compound
InChIKey: JUVIOZPCNVVQFO-HBGVWJBISA-N
SMILES: CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

ReferenceID: 53
"J Goepp" "SD Macknight" "D Rotin" "DY Thomas" "JW Hanrahan" "GW Carlile" "E Matthes" "J Liao" "R Robert" "B Kus"
ReferenceID: 55
"DY Thomas" "JW Hanrahan" "D Zhang" "GW Carlile" "R Robert" "KA Teske" "Y Luo"

chemical graph of compound 44





CID is 6758
synonyms found at PubChem are:
rotenone, 83-79-4, Dactinol, Paraderil, (-)-Rotenone, Tubatoxin, Barbasco, (-)-cis-Rotenone, Derrin, Derris, Cube root, Nicouline, Rotocide, Noxfish, Ronone, Rotenon, Canex, Deril, Liquid Derris, Cube-Pulver, Dri-Kil, Rotessenol, Noxfire, Rotefive, Rotefour, Rotenox, Cubor, Haiari, Mexide, Derris root, Powder and root, Chem-Mite, Pro-nox fish, Cenol garden dust, Curex flea duster, Prenfish, Tubotoxin, Gerane, Prentox, Ro-Ko, Synpren, Derris (insecticide), Chem fish, Pb-nox, Rotenox 5EC, 5'-beta-Rotenone, Green Cross Warble Powder, Chem-Fish Synergized, Prentox Synpren-Fish, Nekoe, Caswell No. 725, Extrax, Cube extract, Foliafume E.C., Fish-Tox, ENT 133, Rotenona [Spanish], Rotenone, commercial, CCRIS 895, Rotenone [BSI:ISO], HSDB 1762, NCI-C55210, 5'beta-Rotenone, EPA Pesticide Chemical Code 071003, UNII-03L9OT429T, AI3-00133, NSC26258, EINECS 201-501-9, NSC 26258, Rotenona, Derris resins, MLS000738056, CHEMBL429023, CHEBI:28201, 03L9OT429T, Rotacide E.C., CUBE, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-alpha-isopropenyl-8,9-dimethoxy-, (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one, (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, (2R-(2alpha,6aalpha,12aalpha))-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)(1)benzopyrano(3,4-b)furo(2,3-h)benzopyran-6(6aH)-one, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12aalpha-Tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, NCGC00017358-05, DSSTox_CID_1248, DSSTox_RID_76038, DSSTox_GSID_21248, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R-(2alpha,6aalpha,12aalpha))-, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-on, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one, Green cross warble, Rotacide, Protax, 5'.beta.-Rotenone, CAS-83-79-4, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, (2R,6aS,12aS)-1,2,6,6a,12,12a- hexahydro-2-isopropenyl-8,9- dimethoxychromeno[3,4-b] furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno(3,4-b)furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one, (2R,6aS,12aS)-2-isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, SR-01000076110, Foliafume, Rotenoid, Roteonone, Nusyn, rote five, WLN: T G5 D6 B666 CV HO MO POT&TT&J IY1&U1 SO1 TO1, Chem-Fish, Foliafume E.C, Rotacide E.C, 5''beta-rotenone, 5'b-Rotenone, Rotocide E.C., (1)Benzopyrano[3,3-h](1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-iospropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6a.alpha.H)-one, 1,2,12,12a.alpha.-tetrahydro-2.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2.alpha.,6a.alpha.,12a.alpha.)]-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2alpha,6aalpha,12aalpha)]-, Derris, JMAF, Prestwick_542, Hydrogenated rotenone, Rotenone (7CI), Rotenone, hydrogenated, Rotenone, >=95%, Spectrum_000065, Spectrum2_000457, Spectrum3_000158, Spectrum4_001638, Spectrum5_000455, D0F7CS, AC1L1N8M, AC1Q4EW8, Lopac0_001112, SCHEMBL42253, BSPBio_001896, isopropenyl(dimethoxy)[?]one, KBioGR_002075, KBioSS_000465, SPECTRUM200013, DivK1c_000947, Rotenone E.C. (7.5%), SPBio_000534, DTXSID6021248, HMS502P09, KBio1_000947, KBio2_000465, KBio2_003033, KBio2_005601, KBio3_001116, inhibits NADH2 oxidation to NAD, NSC8505, JUVIOZPCNVVQFO-HBGVWJBISA-N, MolPort-002-507-351, NINDS_000947, HMS3263O06, 2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-H]chromen-6(6ah)-one, BCP07278, HY-B1756, NSC-8505, TNP00301, ZINC3860715, Tox21_110819, Tox21_201904, Tox21_300695, Tox21_501112, 2901AC, BDBM50135527, CCG-39886, LMPK12060007, MFCD09025614, NSC-26258, SBB006465, AKOS004910398, Tox21_110819_1, API0004105, CS-6067, DB11457, LP01112, LS-1830, MCULE-7287067191, MCULE-7415617623, RL05168, SDCCGMLS-0066415.P001, IDI1_000947, NCGC00017358-01, NCGC00017358-02, NCGC00017358-03, NCGC00017358-04, NCGC00017358-06, NCGC00017358-07, NCGC00017358-08, NCGC00017358-09, NCGC00017358-10, NCGC00017358-11, NCGC00017358-14, NCGC00017358-15, NCGC00094382-01, NCGC00094382-02, NCGC00094382-03, NCGC00094382-04, NCGC00094382-05, NCGC00254603-01, NCGC00259453-01, NCGC00261797-01, AJ-46043, AK115691, AN-24066, AS-10183, NCI60_002093, SC-66514, SMR000393729, ST057261, AX8150549, ST2413787, EU-0101112, R0090, Rotenone, PESTANAL(R), analytical standard, TRANSGENIC MODEL EVALUATION (ROTENONE), C07593, R 8875, 26914-EP2275422A1, 26914-EP2280009A1, 26914-EP2305662A1, 26914-EP2308857A1, 26914-EP2314583A1, 599T610, SR-01000076110-2, SR-01000076110-5, SR-01000076110-6, W-104134, BRD-K08316444-001-01-9, BRD-K08316444-001-05-0, ROTENONE (SEE ALSO TRANSGENICMODEL EVALUATION (ROTENONE)), (1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0^{3,11}.0^{4,8}.0^{14,19}]henicosa-3(11),4(8),9,14(19),15,17-hexaen-12-one, (2R,6a5,12axS)-1,2,12,12a-tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-H)(1)benzopyran-6(6aH)-one, (2r,6as,12as)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxybenzopyrano(3,4-b)furo(2,3-h)benzopyran-6-one, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-one, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy- (8CI), [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)- (9CI), [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-o ne, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h) (1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 9CI, 12679-58-2, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-on e, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Tubatoxin 1,2,12,12a,-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]-benzopyran-6(6aH)-one