previous compound ID: 8 next compound
InChIKey: RDOBOPJBMQURAT-UHFFFAOYSA-N
SMILES: CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CSC(=N3)NC4=C(C=CC(=C4)Cl)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 72
"J Fulton" "SM Rowe" "JP Clancy" "J Collawn" "B Woodworth" "Y Li" "L Fan" "J Fortenberry" "A Jurkevante" "PA Sloane" "LC Pyle" "EJ Sorscher" "K Varga" "M Mazur"
ReferenceID: 85
"D Tondelier" "P Zielenkiewicz" "A Edelman" "N Servel" "A Roldan" "A Kupniewska" "M Ollero" "P Melin-Heschel" "EL Saussereau" "L Wiszniewski" "S Bitam" "M Dadlez" "GL Lukacs" "G Faure" "J Colas" "J Fritsch" "H Herrmann" "F Becq" "K Tarnowski" "N Odolczyk" "MF da Cunha" "C Norez" "G Wieczorek"
ReferenceID: 73
"AI Esposito" "E Caci" "N Pedemonte" "V Tomati" "E Sondo" "LJ Galietta" "U Pfeffer"
ReferenceID: 52
"M Jollivet Souchet" "R Ferru-Clément" "F Becq" "C Boinot"
ReferenceID: 79
"K Du" "GL Lukacs" "E Caci" "AS Verkman" "N Pedemonte" "O Zegarra-Moran" "LJ Galietta"
ReferenceID: 15
"MC Bartlett" "TW Loo" "DM Clarke" "Y Wang"

chemical graph of compound 8




CID is 1144671
synonyms found at PubChem are:
Corr-4a, RDOBOPJBMQURAT-UHFFFAOYSA-N, 421580-53-2, ST075396, N-(2-(5-Chloro-2-methoxyphenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)benzamide, MLS000561131, Oprea1_189688, Oprea1_471654, SCHEMBL837666, CHEMBL260775, DTXSID00360737, MolPort-001-986-142, ZINC888741, AKOS001665304, MCULE-2724995336, BAS 02936954, KB-57187, SMR000156156, EU-0078205, MLS-0094194.0001, SR-01000492559, SR-01000492559-1, N-[2-(5-Chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2' -yl]-benzamide, N-[2-(5-Chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzami, N-[2-(5-Chloro-2-methoxyphenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]benzamide, N-{2-[(5-chloro-2-methoxyphenyl)amino]-4'-methyl-4,5'-bi-1,3-thiazol-2'-yl}benzamide, N-(5-{2-[(5-chloro-2-methoxyphenyl)amino](1,3-thiazol-4-yl)}-4-methyl(1,3-thia zol-2-yl))benzamide